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Silcream
Silver Sulphadiazine 1% is used in the treatment of burns. It is applied on the burnt skin from getting infected.
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✅ Description:
Silver sulfadiazine cream is indicated for the treatment and prophylaxis of infection in various dermatological conditions, including:
- Cuts
- Wounds
- Severe burns
- Post-operative wound dressing
- Bed sores
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✔️ How does Silcream work?
Silver Sulfadiazine is an antibiotic. It stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.
✔️ Uses of Silcream
Cuts, Wounds, Severe burns, Post-operative wound dressing, Bed sores
✔️ Side Effectsof Silcream
- Allergic reactions including burning, itching, and rashes
- Argyria with prolonged use
- Transient leucopenia
✔️ Quick Suggestions:
- Silver Sulfadiazine prevents and treats infections of burn wounds.
- Clean the wound and then apply the cream to the affected area using a sterile gloved hand or a sterile spatula.
- Apply it once or twice daily and re-apply to any areas from which it gets removed due to activity. Burn areas should be covered with the cream at all times.
- Continue to use Silver Sulfadiazine as per the frequency and duration advised by your doctor.
✔️ Mode of Action
Silver sulfadiazine has broad antimicrobial activity against gram-positive and gram-negative bacteria, yeasts, and fungi. It disrupts the integrity of the bacterial cell wall and membrane, leading to cell death by impairing essential enzymes, DNA, and RNA.
✔️ Dosage:
Adult Dose
For topical/cutaneous treatment and prophylaxis of infection in severe burns:
- Apply onto the affected area 1-2 times/day.
Child Dose
- <2 months: Contraindicated
- >2 months (1% cream): Apply onto the affected area 1-2 times/day.
✔️ Administration
- Burns: Clean the burn wound and apply the cream over all affected areas to a depth of 3-5mm. Reapply as necessary, at least every 24 hours or more frequently if there is significant exudate.
- Hand Burns: Enclose the whole hand in a clear plastic bag or glove before applying the cream. Change the dressing when excessive exudate accumulates.
- Leg Ulcers/Pressure Sores: Fill the cavity of the ulcer with cream to a depth of at least 3-5mm. Follow with an absorbent pad or gauze dressing and apply pressure bandaging as appropriate. Change dressings daily or every 48 hours for less exudative wounds.
✔️ Interaction
- Potentiates antidiabetic effect of sulphonylureas
- Not antagonized by PABA
✔️ Precautions & Warnings
- Caution in significant hepatic or renal impairment suspected porphyria, and known sensitivity to systemic sulphonamides
- Potential delay in burn eschar separation and alteration of burn wound appearance
- Use with caution in lactating women, as the distribution of breast milk is not known
✔️ Storage:
Silver Sulfadiazine cream should be kept at room temperature, between 20 and 25 degrees Celsius.
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