Generic Name: Lidocaine Hydrochloride 2%
Company Name: UniMed UniHealth Pharmaceuticals Ltd
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Indications
Lidocaine Jelly is indicated for-
Pharmacology
The main sodium-specific ion channels in the membrane of neuronal cells that lidocaine inhibits are voltage-gated sodium channels. When sodium influx is disturbed and signal conduction is impeded, an action potential cannot form. The cytoplasmic (inner) region is thought to contain the sodium channel's receptor site. Rapidly firing neurons experience neural blockage more quickly than slower-firing neurons because lidocaine binds to sodium channels more readily in an active state. The term for this circumstance is a state-dependent blockage.
Dosage & Administration
Urethral anesthesia:
Interactions
Because the toxic effects of lidocaine and antiarrhythmic medications like tocainide are cumulative, they should be taken with caution in these patients.
Contraindications
It is not recommended for patients who have a history of hypersensitivity to amide-type local anesthetics.
Side Effects
Pregnancy & Lactation
Although there is no or insufficient evidence of the drug's safety in human pregnancy, it has been widely used for many years with no obvious adverse effects. If drug therapy is required during pregnancy, this medicine can be used if no other option is available. Lidocaine does enter the mother's milk, but in such little amounts that the child is rarely affected at therapeutic dose levels.
Precautions & Warnings
Storage Conditions
Store at or below 25°C in a dry, dark area.
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