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Clinosol Gold IV Infusion 500ml
- Sterile aqueous solution for IV infusion.
- Contains 7% amino acids and 10% glucose with electrolytes.
- Provides nitrogen sources essential for protein synthesis and intravenous nutrition.
- Suitable for postoperative periods and extended IV nutrition.
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✅ Description:
Composition (per 100 ml):
- Essential Amino Acids:
- L-Isoleucine: 0.390 gm
- L-Leucine: 0.530 gm
- L-Lysine Hydrochloride: 0.390 gm
- L-Methionine: 0.190 gm
- L-Phenylalanine: 0.550 gm
- L-Threonine: 0.300 gm
- L-Tryptophan: 0.100 gm
- L-Valine: 0.430 gm
- L-Histidine: 0.240 gm
- L-Tyrosine: 0.050 gm
- Non-Essential Amino Acids:
- L-Arginine: 0.330 gm
- L-Aspartic Acid: 0.410 gm
- L-Glutamic Acid: 0.900 gm
- L-Alanine: 0.300 gm
- L-Cystine: 0.140 gm
- Glycine (Aminoacetic Acid): 0.210 gm
- L-Proline: 0.810 gm
- L-Serine: 0.750 gm
- Carbohydrate:
- Anhydrous Glucose: 10.00 gm
- Electrolytes:
- Sodium (Na+): 50.0 mmol/L
- Potassium (K+): 20.0 mmol/L
- Calcium (Ca++): 2.5 mmol/L
- Magnesium (Mg++): 1.5 mmol/L
- Chloride (Cl-): 32.0 mmol/L
Safety Advices
Alcohol
UNSAFE
It is not known whether it is safe to consume alcohol with Clinosol Gold IV Infusion.
Pregnancy
CONSULT YOUR DOCTOR
Clinosol Gold IV Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Clinosol Gold IV Infusion should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
CAUTION
It is not known whether Clinosol Gold IV Infusion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Clinosol Gold IV Infusion should be used with caution in patients with kidney disease. A dose adjustment of Clinosol Gold IV Infusion may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Clinosol Gold IV Infusion should be used with caution in patients with severe liver disease. A dose adjustment of Clinosol Gold IV Infusion may be needed. Please consult your doctor.
✔️ Uses of Clinosol Gold IV Infusion
- Treatment of Nutritional deficiencies
✔️ How does Clinosol Gold IV Infusion work?
The amino acids are an essential element in the diet. The catabolism of Amino acid initiates in muscle and yields NADH and FADH2 which can be utilized for ATP generation.
✔️ Side Effects of Clinosol Gold IV Infusion
- Generally well-tolerated.
- Rare nausea and vomiting.
- Flushing and sweating if infused too quickly.
- Possible transient increases in liver tests.
- Hypersensitivity reactions were reported.
- Thrombophlebitis may occur with peripheral vein use.
- Incidence reduced by concurrent 10% fat emulsion infusion.
✔️ Related lab tests
- Ferritin
- Iron Serum
- Iron Studies
- Vitamin B12
✔️ Indication of Clinosol Gold IV Infusion
- Suitable for adult and pediatric patients needing IV nutrition.
- Provides amino acids, glucose, and electrolytes.
- Meets basal amino acid requirements.
✔️ Pharmacology
As with all intravenous fluid therapies, the primary goal is to provide adequate water to offset insensible losses, urinary losses, and other fluid losses such as those from nasogastric suction, fistula drainage, and diarrhea. Administering the infusion at a rate of 45 mL/kg/day will generally meet the fluid and amino acid needs of a stable adult patient. However, in pediatric patients, especially neonates and those with low birth weight, the dosage and constant infusion rate of intravenous dextrose must be carefully selected to mitigate the increased risk of hyperglycemia or hypoglycemia.
✔️ Administration Advice:
- Administer slowly and avoid exceeding recommended rates.
- Infuse through central or peripheral veins as appropriate.
- Monitor for adverse reactions.
✔️ Pharmacology
- Promotes protein synthesis and wound healing.
- Reduces endogenous protein catabolism.
- Can be used with dextrose, electrolytes, vitamins, trace metals, and fat supplements for total parenteral nutrition (TPN).
- Suitable for central venous or peripheral vein administration.
✔️ Dosage & Administration of Clinosol Gold IV Infusion
- Adults:
- Nitrogen requirements vary based on the patient's condition.
- Dosage range: 0.10-0.25 g nitrogen/kg/day (11-27 ml/kg/day).
- Infusion rate: Not exceeding 500 ml in 3 hours (1.4-2.8 ml/min).
- Typical volume: 1000-2000 ml per 24 hours.
- Infants and Children:
- Maximum infusion rate: 30 ml/kg body weight/day.
- Gradual increase in infusion rate during the first week of treatment.
✔️ Interaction
Expected not to interact with other medications at the recommended dosage.
✔️ Contraindications
- Inborn errors of amino acid metabolism.
- Severe liver damage.
- Severe uremia without dialysis facilities.
- Hyperosmolar nonketotic diabetic coma.
- Known hypersensitivity to any ingredients.
✔️ Pregnancy & Lactation
- Safe administration during pregnancy was reported.
- No animal reproduction studies were conducted.
✔️ Precautions & Warnings
- Monitor phenylalanine levels in premature infants.
- Use cautiously in patients with diabetes, severe heart failure, or renal function issues.
- Exogenous insulin may be necessary for hyperglycemia.
- Do not use if the solution is turbid or contains particles.
- Discard any unused portion.
✔️ Storage:
- Store between 15°C to 25°C.
- Protect from light and avoid freezing.
- Keep out of reach of children.
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lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
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