Dhea 25 | Uses, Dosage, Side-Effects, FAQ | Price | Hormone Medicine
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Dhea 25mg Tablet 10pcs

Generic: Dehydroepiandrosterone

Type: Tablet

Pack Size: 10pcs

Dhea 25mg Tablet contains ‘Dehydroepiandrosterone’, which is a hormone. It increases the chances of pregnancy by regulating of ovulation process (release of eggs from the ovary). 


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Discount Price: ৳ 138
MRP: ৳ 150 8% Off

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✅ Description:

  • Cognitive Function and Physical Strength: Lack of evidence to support improvement in cognitive function or physical strength in elderly patients.
  • Postmenopausal Symptoms, Hyperlipidemia, Insulin Resistance, Schizophrenia, Cancer: No convincing evidence to support a place in therapy.
  • Diminished Ovarian Reserves: Some evidence supports use in women with diminished ovarian reserves.
  • Osteoporosis in Elderly Women: Limited support in subpopulations of elderly women with osteoporosis.
  • Systemic Lupus Erythematosus: Mild systemic lupus erythematosus may see some benefit.
  • Major Depressive Disorder: Recommended as third-line monotherapy or adjunctive therapy; potential role as an anxiolytic.

Safety Advices


Alcohol
UNSAFE

No information is available on interactions of this medicine when taken with alcohol, consult your doctor or pharmacist for further information.


Pregnancy
CONSULT YOUR DOCTOR

Dhea 25mg Tablet can harm the unborn baby, therefore avoid this medicine during pregnancy.


Breastfeeding
CONSULT YOUR DOCTOR

Dhea 25mg Tablet can pass into breast milk and may cause adverse effects in breastfed babies. Therefore avoid this medicine if you are breastfeeding.


Driving
CAUTION

Taking Dhea 25mg Tablet usually doesn’t affect the ability to drive.


Kidney
CONSULT YOUR DOCTOR

Dhea 25mg Tablet should be used with caution in patients with kidney diseases. Your doctor may adjust the dose based on your condition.


Liver
CONSULT YOUR DOCTOR

Dhea 25mg Tablet should be used with caution in patients with liver diseases as it may cause liver damage and worsen your condition.

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✔️ Uses of Dhea 25mg Tablet
  • Female Infertility
✔️ How does Dhea 25mg Tablet work?

DHEA is a neurosteroid that is naturally synthesized by the human body and acts on specific tissues or cells in the body.

✔️ Side Effects of Dhea 25mg Tablet

Generally well-tolerated, but observed adverse effects include mania, hypomania, acne, hirsutism, gynecomastia, testicular changes, increased blood pressure, and decreased HDL levels.

  • Use caution in individuals with psychiatric disorders, diabetes, liver dysfunction, and polycystic ovarian syndrome.
✔️ Mode of Action:
  • Sulfate derivative acts as a noncompetitive antagonist of GABA receptors and a positive allosteric modulator of NMDA receptors.
  • Neuroprotective, antioxidant, antihypertensive, and anti-inflammatory effects are reported in humans.
  • Serum DHEA levels peak 60 to 480 minutes after administration.
✔️ Infertility:
  • Infertility is the failure to achieve pregnancy after 12 months or more of regular unprotected sex.
  • Approximately one in every six people of reproductive age worldwide experience infertility.
  • Causes of male infertility include problems in semen ejection, low sperm levels, abnormal sperm morphology, and motility.
  • Female infertility causes include tubal disorders, uterine issues, ovarian disorders, and endocrine system imbalances.
  • Infertility can be primary (no prior pregnancy) or secondary (at least one prior pregnancy).
  • Fertility care includes prevention, diagnosis, and treatment, but access is a challenge in many countries.

Causes of Infertility:

  • Female causes: tubal disorders, uterine issues, ovarian disorders, and endocrine system imbalances.
  • Male causes: reproductive tract obstruction, hormonal disorders, testicular failure, and abnormal sperm function.
  • Lifestyle factors like smoking, alcohol, obesity, and exposure to pollutants can affect fertility.

Diagnosis:

  • Female infertility diagnosis involves pelvic exams, blood tests, ultrasounds, hysteroscopy, and laparoscopy.
  • Male infertility diagnosis includes semen analysis, blood tests, and scrotal ultrasound.

Treatment:

  • Lifestyle modifications, medications, surgery, and assisted reproductive technology (ART) are common treatments.
  • ART includes in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), intrauterine insemination (IUI), and assisted hatching.
  • Complications of treatment include a higher chance of multiples, ovarian hyperstimulation syndrome (OHSS), ectopic pregnancy, and failed cycles.

Complications:

  • A higher chance of multiples, OHSS, ectopic pregnancy, and failed cycles are potential complications of infertility treatment.
  • Success rates vary, but many cases can be treated, with 85-90% having successful outcomes.

Prevention:

  • Prevention involves lifestyle modifications, regular health check-ups, and awareness of reproductive health.

Outlook:

  • Success in treating infertility depends on the cause; lifestyle changes, medications, surgery, or ART can be effective.
  • Access to fertility care remains a challenge, especially in low and middle-income countries.

Living With Infertility:

  • Infertility can be emotionally challenging; support from healthcare professionals and support groups is essential.
  • Treatment may involve multiple attempts, and emotional well-being is crucial during the process.
✔️ Preventing Infertility:
  • Eat a well-balanced diet with a focus on essential nutrients.
  • Maintain a weight that is healthy for your body type.
  • Quit smoking, avoid drug misuse, and limit alcohol consumption.
  • Substance abuse can negatively impact fertility.
  • Get timely treatment for STIs to prevent complications that may affect fertility.
  • Limit exposure to environmental toxins and pollutants.
  • Be cautious of workplace or household substances that may impact reproductive health.
  • Stay physically active, but avoid excessive exercise that may impact reproductive functions.
  • Maintain a healthy balance to support overall well-being.
  • Don't delay conception until an advanced age.
  • Female fertility tends to decline with age, so early family planning may enhance the chances of conception.
  • Schedule regular health check-ups to address any underlying health conditions that might impact fertility.
  • Early detection and management of health issues can contribute to reproductive well-being.
  • Seek advice from healthcare professionals, especially if planning pregnancy.
  • Discuss family planning, fertility concerns, and potential risk factors with your healthcare provider.
  • Manage stress levels and maintain emotional well-being.
  • Emotional health can play a role in reproductive health.
  • If there's a family history of genetic disorders, consider genetic counseling before conception.
✔️ Dosage & Administration:
  • Adrenal Insufficiency: Replacement dose is 50 mg/day for 3 months; 200 mg/day achieves supraphysiological levels.
  • Anorexia Nervosa: 100 mg/day for 6 months in a pilot study.
  • Diminished Ovarian Reserve: 50 to 75 mg/day in divided doses in assisted reproduction.
  • Exercise Training–Induced Muscle Damage: 100 mg/day over 5 days in young men undergoing exercise training.
  • Major Depressive Disorder: Doses range from 30 to 450 mg/day for 6 to 8 weeks.
  • Metabolic Syndrome: 100 mg/day for 3 months in a study evaluating effects against metabolic syndrome.
  • Postmenopausal Women: Suggested 25 mg/day to minimize androgenic adverse effects; positive outcomes seen at doses of at least 50 mg/day.
✔️ Interaction

Supraphysiologic serum DHEAS levels can interfere with progesterone assays, leading to false-positive increases in serum progesterone.

✔️ Do not take Dehydroepiandrosterone if you have:
  • Breast cancer
  • Prostate cancer
  • PCOS/ PCOD
✔️ Pregnancy & Lactation

Information lacking regarding safety and efficacy in pregnancy and lactation. Dhea 25 mg supplementation was evaluated for improving oocyte production in infertility.

✔️ Precautions & Warnings
  • DHEA can reduce high-density cholesterol (HDL), known as good cholesterol. Caution in use for individuals with high cholesterol levels.
  • Prolonged or high-dose use may increase the risk of cancers. Use only under a doctor's prescription and supervision.
  • May cause urination problems in individuals with an enlarged prostate. Consult a healthcare professional if such issues arise.
  • Exercise caution in individuals with heart problems, liver diseases, and blood clotting issues. Potential worsening of conditions may occur.
  • DHEA may impact PCOS, causing enlarged ovaries and irregular menstrual periods. Use under guidance, especially in individuals with PCOS.
✔️ Storage Conditions

Keep below 30°C, away from light and moisture. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

No

Complications of treatment include the risk of multiples, OHSS, ectopic pregnancy, and failed cycles.

Causes and treatments vary, and success rates depend on the specific case.

Female Infertility can be cured in most cases by an appropriate therapy such as medicines, surgery, assisted reproductive technology (ART) such as in-vitro fertilization (IVF), or a combination of these therapies. The doctor will suggest a suitable treatment depending on the cause of your infertility.

Bone Density: May contribute to improved bone density. Body Fat Reduction: Potential to decrease body fat. Sexual Function: Could enhance sexual function. Relevance for Certain Groups: Potential benefits for older adults. Considered for individuals with specific health conditions. Natural Production: Typically unnecessary for young, healthy individuals. The body naturally produces sufficient DHEA.

Dhea 25 supplementation is associated with enhanced ovarian environment for follicle maturation.

Yes

Normal DHEA-Sulfate Levels: For Females: Ages 18 to 19: 145 to 395 µg/dL or 3.92 to 10.66 µmol/L. Ages 20 to 29: 65 to 380 µg/dL or 1.75 to 10.26 µmol/L. Ages 30 to 39: 45 to 270 µg/dL or 1.22 to 7.29 µmol/L. Ages 40 to 49: 32 to 240 µg/dL or 0.86 to 6.48 µmol/L. Ages 50 to 59: 26 to 200 µg/dL or 0.70 to 5.40 µmol/L. Ages 60 to 69: 13 to 130 µg/dL or 0.35 to 3.51 µmol/L. Ages 69 and older: 17 to 90 µg/dL or 0.46 to 2.43 µmol/L. For Males: Ages 18 to 19: 108 to 441 µg/dL or 2.92 to 11.91 µmol/L. Ages 20 to 29: 280 to 640 µg/dL or 7.56 to 17.28 µmol/L. Ages 30 to 39: 120 to 520 µg/dL or 3.24 to 14.04 µmol/L. Ages 40 to 49: 95 to 530 µg/dL or 2.56 to 14.31 µmol/L. Ages 50 to 59: 70 to 310 µg/dL or 1.89 to 8.37 µmol/L. Ages 60 to 69: 42 to 290 µg/dL or 1.13 to 7.83 µmol/L. Ages 69 and older: 28 to 175 µg/dL or 0.76 to 4.72 µmol/L.

Do not take Dhea 25 if you have diabetes or have an enlarged prostate.

Yes
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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