Tablet, Manufactuer Incepta Pharmaceuticals Ltd. Generic Name: Glucosamine Sulfate 150 mg + Chondroitin Sulfate 120 mg + Undenatured Type II Collagen 40 mg
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Synogen Plus Tablet: Each tablet contains Glucosamine Sulfate USP 150 mg, Chondroitin Sulfate USP 120 mg and Undenatured Type II Collagen 40 mg.
Description
Glucosamine is a naturally occurring amino sugar of cartilage that provides the basic raw material needed by the body to manufacture joint cartilage. Chondroitin is another naturally occurring mucopolysaccharide of cartilage that stimulates cartilage production, inhibits cartilage destroying enzymes, draws fluid to the cells and helps lubricate the joints. Glucosamine and Chondroitin work synergistically together to help stimulate the production and regeneration of connective tissues (e.g., cartilage, bone, tendon, skin, mucous membrane, blood vessels etc.). Undenatured Type II Collagen also known as Chicken Collagen Type II that works by oral tolerization. This Undenatured type II Collagen contains epitopes that interacts with the peyer’s patch in the intestine. It prevents the immune system from releasing destructive collagen specific T-cell. This T-cell is responsible for degradation of collagen in the joints. This causes halting the erosion of joint cartilage. As inflammation subsides the disequilibrium of cartilage turnover shifts in favor of rebuilding. It appears that once the destructive cycle is broken, the joint cartilage begins to repair itself through collagen building activities that are part of normal cartilage remodelling process.
Indications
The drug is indicated to treat osteoarthritis, rheumatoid arthritis, other joint pain & inflammation associated with injury and impaired joint function.
Dosage & Administration
1 tablet daily with meal or as directed by the physician.
Side Effects
Generally safe for most of the people but some may feel stomach problems.
Use in Pregnancy & Lactation
There is not enough reliable information about the safety of taking the drug if you are pregnant or breast-feeding. So it is better to avoid the drug during pregnancy and lactation.
Drug Interaction
There is no known drug interaction with Undenatured type II Collagen, Glucosamine and Chondroitin.
Over Dose
Abdominal discomfort may happen in case of overdose of drug.
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