Type: Tab. Generic Name:Clomipramine hydrochloride 25mg/tablet. Manufacturer/Distributor: Novartis
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Indications of Anafranil 25 Tablet
Clomipramine Hydrochloride is utilized to treat sadness, fixations and fears (silly fears). It is additionally utilized to treat solid shortcoming (cataplexy) related with rehash assaults of extraordinary languor (narcolepsy) in grown-ups.
Pharmacology of Anafranil 25 Tablet
Clomipramine hydrochloride has a place to a gather of solutions called "tricyclic antidepressants". Typically thought to work either by increasing the sum of chemical "couriers" within the brain or by making their impacts last longer. Clomipramine may be a strong inhibitor of serotonin re-uptake within the brain. Noteworthy hostility at cholinergic and α1-receptors. Frail hostility at dopamine receptors. It has too upper, narcotic and anticholinergic effects.
Dosage of Anafranil 25 Tablet
The usual dosages for adults are as follows:
For depression: 10 mg to 150 mg daily. Severe cases may need even higher doses.
For obsessions and phobias: 10 mg to 150 mg daily.
For cataplexy: 10 mg to 75 mg daily.
The elderly: Elderly patients often need a lower dose because they are more likely to experience side effects.
Administration of Anafranil 25 Tablet
Swallow this capsules whole with a drink of water. Keep taking your medicine until your doctor tells you to stop. Do not stop because you do not feel any better. This medicine may take up to 4 weeks to work. The medicine may be taken as one dose at night or as smaller doses at intervals during the day.
Interaction of Anafranil 25 Tablet
Do not take this if you are currently using or have just stopped taking monoamine oxidase inhibitors (MAOIs), which are antidepressant medications.
Contraindications
Known hypersensitivity to clomipramine and any of the excipients in the tablets.
Cross-hypersensitivity to tricyclic antidepressants of the dibenzazepine group.
Concomitant use with a monoamine oxidase (MAO) inhibitor, or within 14 days before or after treatment with an irreversible MAO inhibitor, or within 14 days before moclobemide, a reversible MAO inhibitor.
Acute and recovery stages of myocardial infarction.
Congenital long QT syndrome.
Side Effects of Anafranil 25 Tablet
Exceptionally common side impacts are increment in craving and weight pick up, migraines, tipsiness, sickness, clogging, dry mouth, expanded sweating, shaking hands, tremor, trouble in passing pee, issues with their eyes, feeling tired or languid, sexual unsettling influences, eagerness.
Pregnancy & Lactation
Clomipramine enters into human milk, so newborns should be weaned or clomipramine should be progressively discontinued.
Precautions & Warnings
Check with your doctor or pharmacist before taking your medicine if:
you have epilepsy (fits)
you have an overactive thyroid gland
you have a tumour (cancer) of the adrenal gland (such as phaeochromocytoma or neuroblastoma)
you have low blood pressure
you wear contact lenses
you have had severe constipation for a long time
you find yourself thinking about suicide
you have had a head injury and suffered brain damage
you are going to have ECT (electroconvulsive therapy)
you have an irregular heartbeat or other problems with your heart
you have been diagnosed as having a low level of potassium in your blood (hypokalemia)
you have schizophrenia or any other mental disorder
you are elderly
you have glaucoma(increased pressure in the eye)
you have liver or kidney disease
you have any blood disorder
you have difficulties in passing urine (e.g. due to diseases of the prostate)
Therapeutic Class
Tricyclic & related anti-depressant drugs
Storage Conditions
Keep in a cool & dry place (below 30° C), protected from light & moisture. Keep out of the reach of children.
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