Solas Oral Suspension 30ml

✔️ Uses of Solas Oral Suspension

Treats Parasitic worm infections like:

• Threadworms (also called pinworms) or
• Other common worm infections (Ex. whipworm, roundworm, hookworm)

✔️ How does Solas Oral Suspension work?

‘Mebendazole’, which works by inhibiting tubulin polymerization. This causes metabolic disruption and energy depletion in the parasite, which leads to its immobilization. Thereby, Solas Oral Suspension kills the susceptible helminth and treats the infection. 

✔️ Side Effects of Solas Oral Suspension

• Diarrhea
• Stomach discomfort and pain
• Nausea and Vomiting
• Loss of appetite
• Difficulty in breathing
• Fever with chills
• Difficulty in swallowing
• Peeling and blistering of the skin
• Hair loss or thinning of the hair
• Swelling of eyelids, face, lips, tongue
• Sore throat and hoarseness
• Joint or muscle pain
• Weight loss

✔️ Quick Suggestions:

• Wash your hands regularly with soap and water, especially after using the toilet and before eating.
• Avoid eating raw fish and meat.
• Thoroughly cook meat before consuming it.
• Properly wash all fruits and vegetables before eating them.
• Wash or reheat food that has been stored for a long time.
• Avoid contact with soil that may be contaminated with feces.
• Avoid consuming foods that have been kept open in markets as they may be contaminated.
• Drink boiled and purified water.
• Take Solas with food.
• If you have difficulty swallowing the whole tablet, you can crush or chew it and swallow it with a full glass of water.
• Avoid taking Solas during pregnancy or breastfeeding. Use appropriate birth control measures to prevent pregnancy while taking the medication.
• Your doctor may monitor your blood counts and liver function before and during treatment with Solas.
• Avoid close contact with sick individuals or those with infections. Notify your doctor if you develop signs of infection.
• Do not skip doses of Solas and complete the full prescribed course, even if you start feeling better. Stopping the medication early may increase the risk of further infection.

✔️ Indication

Whipworm infection

This medicine is used for the treatment of Whipworm infection caused by the Trichuris trichiura strain.

Hookworm infection

• This medicine is used for the treatment of Hookworm infection caused by Necator americanus and Ancylostoma duodenale strains.

Pinworm infection

• This medicine is used for the treatment of pinworm infection caused by Enterobius vermicularis strain.

Roundworm infection

• This medicine is used for the treatment of roundworm infection caused by the Ascaris lumbricoides strain.

Other parasitic infections

• This medicine is also used for other infections caused due to helminths. Infections treated may include Giardiasis, Filariasis, Toxocariasis, Hydatid disease, etc.

✔️ Pharmacology

Mebendazole is indeed a synthetic broad-spectrum anthelmintic drug that is effective against a variety of parasitic worms, including nematodes. Its mechanism of action involves preventing the worms from forming microtubules, which ultimately leads to the depletion of glucose and energy within the worms, resulting in their death.

When taken orally, Mebendazole is absorbed by the gastrointestinal tract, with approximately 2-10% of the oral dose being absorbed. The peak concentration of Mebendazole in the plasma occurs between 30 minutes to 7 hours after administration.

Mebendazole has a strong affinity for plasma proteins, which means that it binds to proteins in the blood. The half-life of elimination, which refers to the time it takes for half of the drug to be eliminated from the body, ranges from 2.8 to 9 hours.

It's important to note that individual pharmacokinetic parameters may vary based on factors such as age, metabolism, and other individual characteristics.

✔️ Dosage & Administration of Solas Oral Suspension

Here is a summary of the recommended doses for adults and children:

Adult Dose:

• Enterobiasis (Pinworms): A single tablet (100 mg) or 1 teaspoonful (5 ml) of the suspension. If a cure is not achieved after 3 weeks, a second course of treatment is advised.
• Ascariasis, Ancylostomiasis, Trichuriasis: 100 mg twice daily (bid) for 3 consecutive days, 500 mg as a single dose, or 1 teaspoonful (5 ml) twice daily for 3 consecutive days. If a cure is not achieved after 3 weeks, a second course of treatment is advised.
• Taeniasis & Strongyloidiasis: 100 mg twice daily for 3 consecutive days. If a cure is not achieved after 3 weeks, a second course of treatment is advised.

Child Dose:

• Enterobiasis (Pinworms): Children older than 2 years can take a single tablet (100 mg) or 1 teaspoonful (5 ml) of the suspension. If a cure is not achieved after 3 weeks, a second course of treatment is advised.
• Ascariasis, Ancylostomiasis, Trichuriasis: Children older than 1 year can take 100 mg twice daily for 3 consecutive days or 500 mg as a single dose, or 1 teaspoonful (5 ml) twice daily for 3 consecutive days. If a cure is not achieved after 3 weeks, a second course of treatment is advised.
• Taeniasis & Strongyloidiasis: Children can take 100 mg twice daily for 3 consecutive days. If a cure is not achieved after 3 weeks, a second course of treatment is advised.

It is important to take Solas Oral Suspension as advised by your physician. Shake the suspension well before use. The proper dose and duration of therapy will be determined by your doctor based on your age, body weight, and the type of worm infection you have.

✔️ Interaction

Drug-Drug Interactions:

• Antacid (cimetidine): There may be a potential interaction between Solas Oral Suspension and antacids such as cimetidine. It is advisable to consult with your doctor or pharmacist regarding the timing of taking these medications to minimize any potential interaction.
• A drug used to treat epilepsy (carbamazepine): Solas Oral Suspension may interact with carbamazepine, which is a medication used to treat epilepsy. It is important to inform your doctor about all the medications you are taking, including carbamazepine, to determine the appropriate course of action.
• Antibiotics (metronidazole): There may be a potential interaction between Solas Oral Suspension and metronidazole, which is an antibiotic. Your doctor will consider the potential interaction and adjust the treatment plan accordingly if both medications are necessary.
• Antivirals (ritonavir): Solas Oral Suspension may interact with ritonavir, which is an antiviral medication. It is essential to inform your doctor if you are taking ritonavir or any other antiviral medication to ensure appropriate management and dosage adjustments if needed.

Drug-Food Interactions: 

• It is always recommended to follow any dietary instructions provided by your doctor or pharmacist.

Drug-Disease Interactions: 

• Solas Oral Suspension may have interactions with liver disease. If you have a history of liver disease or any liver-related conditions, it is important to inform your doctor before taking Solas Oral Suspension. Your doctor will consider the potential risks and benefits and may adjust the dosage or choose an alternative treatment option if necessary.

✔️ Contraindications

• Patients who have a known hypersensitivity to Mebendazole or any component of the formulation should not take it.
• Infants and children <2 yr.

✔️ Pregnancy & Lactation

Mebendazole should not be used by pregnant women. Mebendazole is not known to be excreted in human milk. Because many medications are excreted in human milk, it's important to use caution while giving it to a nursing mother.

✔️ Precautions & Warnings

• Maintain proper hygiene to reduce the chances of infection and avoid contact with people who have infections, the flu, or a cold.
• Consult your doctor if you notice unusual bleeding or bruising, as Solas Oral Suspension may increase the risk of these symptoms.
• Solas Oral Suspension will not treat viral infections like the flu or the common cold.
• Regular monitoring of blood cell count and liver function is advised during treatment with Solas Oral Suspension. Close monitoring of liver function is recommended every two weeks.
• Solas Oral Suspension might increase the chances of getting an infection. It is important to maintain proper hygiene and try to stay away from people who have infections, flu, or colds.
• Consult your doctor if you notice unusual bleeding or bruising while taking Solas Oral Suspension The medication may increase the risk of bleeding or bruising easily.
• Do not take Solas Oral Suspension if you have any allergies, liver problems, or intestinal problems. It is important to inform your doctor about your medical history before taking the medication.
• If you are pregnant or planning for pregnant, inform your doctor before taking Solas Oral Suspension. The medication may cause harm to the fetus.
• If you are a breastfeeding mother, immediately contact your doctor because Solas Oral Suspension passes into breast milk. Your doctor will provide guidance on whether it is safe to use the medication while breastfeeding.
• Solas Oral Suspension can be given to children above 2 years if prescribed by a doctor. The dosage and administration should be determined by a healthcare professional.

✔️ Storage Conditions

Store in a cool (below 25°C) and dry location away from direct sunlight. Keep out of children's reach.