✅ Description:
Indications
Nasal congestion caused by acute or chronic rhinitis, the common cold, sinusitis, upper respiratory allergies, epistaxis, and hay fever is treated with Oxymetazoline Hydrochlorid. It's also used to treat otitis media as a nasal decongestant.
Pharmacology
Oxymetazoline Hydrochloride is a sympathomimetic amine that is derived from imidazoline. It acts as a direct agonist on -adrenoceptors but not on -adrenoceptors. When applied topically to the nasal mucosa, it causes a quick and long-acting vasoconstriction of the arterioles, which reduces blood flow and reduces mucosal edema. As a result, the airway's potency improves, and the nasal sinuses drain more effectively.
Dosage and Administration
Oxymetazoline nasal spray-
Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.
Elderly: There is no need for dosage reduction in the elderly for nasal administration.
Children below 6 years of age: It is not suitable for children below 6 years of age.
Oxymetazoline nasal drop-
Adults & children 6 years of age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.
Children 2-5 years of age: 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening
Interaction
Patients taking MAO inhibitors or those who have just stopped taking them should not use Oxymetazoline Hydrochloride Nasal Preparation.
Contraindications
Oxymetazoline Hydrochloride is a sympathomimetic amine that is derived from imidazoline. It acts as a direct agonist on -adrenoceptors but not on -adrenoceptors. When applied topically to the nasal mucosa, it causes a quick and long-acting vasoconstriction of the arterioles, which reduces blood flow and reduces mucosal edema. As a result, the airway's potency improves, and the nasal sinuses drain more effectively.
Side Effects
It can cause local irritation and dryness of the mouth and throat on occasion. Burning, stinging, sneezing, or an increase in nasal discharge may occur for a short time.
Pregnancy & Lactation
Although the safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and breastfeeding has not been proved, it is not believed to pose a risk during these times.
Precautions & Warnings
Oxymetazoline Hydrochloride is a sympathomimetic amine that is derived from imidazoline. It acts as a direct agonist on -adrenoceptors but not on -adrenoceptors. When applied topically to the nasal mucosa, it causes a quick and long-acting vasoconstriction of the arterioles, which reduces blood flow and reduces mucosal edema. As a result, the airway's potency improves, and the nasal sinuses drain more effectively.
Storage Conditions
Protect from light and store below 30° C in a dry area. Do not freeze or refrigerate. Keep out of children's reach.
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