Silver Sulfadiazine cream is indicated for:
Silcream 1% Cream is an antibiotic medication primarily used to treat bacterial and wound infections caused by serious burns. It is also effective in treating infected leg ulcers and pressure sores. Burns are classified based on their size and depth, ranging from minor to severe.
Silcream 1% Cream contains Silver Sulfadiazine, classified as a 'sulfa antibiotic.' It acts as a bactericidal agent, killing bacteria, and is also effective against yeast. By inhibiting the production of folic acid, essential for bacterial multiplication, and acting on the bacterial cell wall and membrane, it reduces the risk of bacterial spread and severe blood infections (sepsis).
Silcream 1% Cream is for external use only. Apply it to burn wounds continuously and cover the treated area with dressings or bandages if advised by your doctor.
Inform your doctor if you have glucose-6-phosphate dehydrogenase deficiency, low white blood cell count, or liver and kidney problems before using Silcream 1% Cream. If you are pregnant or planning to conceive, consult your doctor before using Silcream 1% Cream, as it may affect the unborn baby. Seek medical advice if you are breastfeeding before using Silcream 1% Cream.
The interaction of Silcream 1% Creamwith alcohol is unknown. Please consult a doctor before consuming alcohol while using Silcream 1% Cream.
Limited information is available on how Silcream 1% Cream affects pregnancy. Consult a doctor if you are pregnant before using Silcream 1% Cream.
Consult your doctor before using Silcream 1% Cream if you are breastfeeding. However, if you need to apply SILVER SULFADIAZINE to your breasts, avoid doing so shortly before feeding your baby.
Silcream 1% Cream is generally safe to use before driving. However, if you experience side effects like dizziness or a burning sensation in the affected areas, refrain from driving and operating machinery until you feel better.
Inform your doctor if you have any history of kidney diseases before using Silcream 1% Cream.
Inform your doctor if you have any history of liver diseases before using Silcream 1% Cream.
Silcream 1% Cream acts on the cell wall and cell membrane of the bacteria to cause their death.
Transient leukopenia, skin necrosis, erythema multiform, skin discoloration, burning sensation, rashes, and interstitial nephritis.
Silcream 1% Cream is used for the prevention and treatment of wound infections in patients with second and third-degree burns.
The mechanism of Silver Sulfadiazine's antibacterial action involves structural changes in bacterial cell membranes, including distortion and enlargement, weakening of the cell wall membrane, and reduced viability in sensitive strains. The silver moiety binds to bacterial cells, attaches to DNA, and prevents bacterial cell proliferation. Sulfadiazine provides bacteriostatic action against sensitive organisms.
Missed Dose
Use/apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
An overdose of Silcream 1% Cream is not likely to cause severe symptoms. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
Pregnancy Category B. Use during pregnancy only if justified. It is not known whether Silver Sulfadiazine is excreted in human milk.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.