Imuran 25mg Tablet | ePharma
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Imuran 25mg Tablet

Generic: Azathioprine

Type: Tablet

Pack Size: 25S

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Azathioprine/Imuran is used for preventing organ rejection in transplant patients, treating rheumatoid arthritis, and managing autoimmune diseases.


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Discount Price: ৳ 624
MRP: ৳ 650 4% Off

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✅ Description:

Imuran (azathioprine) is an immunosuppressant medication used to prevent rejection of transplanted organs, treat autoimmune diseases like rheumatoid arthritis, and prevent rejection in organ and tissue transplantation. It works by weakening the body's immune system, thereby reducing the risk of the body attacking the transplanted organ.

Safety Advices


Alcohol
UNSAFE

It is not known whether it is safe to consume alcohol with Imuran. Consult your doctor.


Pregnancy
CONSULT YOUR DOCTOR

Imuran is unsafe to use during pregnancy due to the risk of harm to the developing baby. However, in life-threatening situations, a doctor may prescribe it if the benefits outweigh the risks. Consult your doctor if you are pregnant or planning pregnancy.


Breastfeeding
CONSULT YOUR DOCTOR

Imuran may pass into breast milk and harm the baby. It is probably unsafe to use during breastfeeding. Consult your doctor.


Driving
CAUTION

It is not known whether Imuran affects driving ability. Avoid driving if you experience symptoms that affect concentration and reaction.


Kidney
CAUTION

Use Imuran with caution in patients with kidney disease. Dose adjustment may be necessary. Consult your doctor.


Liver
CAUTION

Use Imuran with caution in patients with liver disease. Dose adjustment may be needed. Regular monitoring of liver function tests is advisable. Avoid Imuran in severe liver disease.

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✔️ Uses of
  • Treatment of organ transplants and a few autoimmune diseases. 
✔️ How does

Imuran inhibits DNA, RNA, and protein synthesis, suppressing the body's immune response. It also blocks certain chemical messengers responsible for inflammation in joint diseases.

✔️ Side Effects of
  • Common side effects include depression of bone marrow function, leucopenia, thrombocytopenia, and nausea.
  • Serious adverse effects include infections, neoplasms, and hypersensitivity reactions.
✔️ Quick Suggestions:
  • Imuran belongs to a group of medicines called immunosuppressants.
  • It prevents rejection of transplanted organs by weakening the immune system.
  • Take it regularly with food as prescribed by your doctor. Take Imuran as advised by your doctor, usually with food. Do not crush, chew, or break the tablets.
  • Imuran may interact with other drugs, increasing the risk of hematotoxicity or infections. Inform your doctor about all medications you are taking.
✔️ Indications:

Azathioprine) is an immunosuppressant medication used either alone or in combination with other agents, such as corticosteroids, to influence the immune response. 

  • Organ Transplant: Imuran Tablet is used to enhance the survival of organ transplants, such as renal, cardiac, and hepatic transplants. It can also reduce the corticosteroid requirements of renal transplant recipients.
  • Inflammatory Bowel Disease (IBD): Imuran Tablet is indicated for the treatment of moderate to severe IBD (Crohn's disease or ulcerative colitis) in patients who require corticosteroid therapy, cannot tolerate it, or have refractory disease.
  • Other Conditions: Imuran Tablet has been used with clinical benefit in conditions like severe active rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, polymyositis, autoimmune chronic active hepatitis, pemphigus vulgaris, polyarteritis nodosa, autoimmune hemolytic anemia, and chronic refractory idiopathic thrombocytopenic purpura.
✔️ Pharmacology
  • Imuran Tablet is an immunosuppressive antimetabolite that inhibits DNA, RNA, and protein synthesis.
  • It is rapidly broken down in vivo into 6-mercaptopurine (6-MP) and amethylnitroimidazole.
  • 6-MP is converted intracellularly into active purine thioanalogues.
  • The therapeutic effect may take weeks or months to manifest.
✔️ Dosage & Administration:
  • For transplants: Initial dosage up to 5mg/kg body weight/day, then maintenance dosage ranging from 1 to 4mg/kg body weight/day.
  • For other indications: Starting dosage of 1 to 3mg/kg body weight/day, adjusted based on clinical response and tolerance.

Administration:

  • Oral use, at least 1 hour before or 2 hours after milk or dairy products.
  • Standardize the method of administration; avoid milk or dairy products.
✔️ Interaction
  • Concomitant use with allopurinol, oxipurinol, or thiopurinol requires reducing Imuran Tablet dosage.
  • Neuromuscular blocking agents may interact with Imuran Tablet.
  • Interactions with anticoagulants, cytostatic/myelosuppressive agents, methotrexate, vaccines, ribavirin, and aminosalicylate derivatives should be considered.
✔️ Contraindications
  • Hypersensitivity to azathioprine or 6-mercaptopurine.
  • Hypersensitivity to any excipients of the preparation.
✔️ Pregnancy & Lactation
  • Imuran Tablet is classified as Pregnancy Category D.
  • It should not be given to pregnant patients without careful assessment of risk versus benefits.
  • Effective contraceptive measures should be used during treatment and for a period after completion of treatment.
  • Breastfeeding is not recommended due to the presence of 6-mercaptopurine in breast milk.
✔️ Precautions & Warnings

Imuran increases the risk of serious infections and neoplasia. Monitor blood cell counts regularly. Use caution in patients with liver or kidney impairment. Avoid Imuran in patients with thiopurine methyltransferase deficiency.

✔️ Storage Conditions

Store below 25°C. Protect from light. Discard off the expired and unused medicine appropriately.

Frequently Asked Questions (FAQ)

Imuran Tablet is used in the management of organ transplantation. It assists the body in accepting a transplanted organ such as a kidney, liver, heart, lung, or pancreas. Additionally, it is beneficial in treating some autoimmune diseases, including severe inflammatory conditions of the skin, liver, arteries, and blood disorders.

No, Imuran is not a steroid. It contains a medicine called Azathioprine, which is an immunosuppressant. It works by reducing the strength of the immune system and is effective in managing autoimmune diseases like severe inflammatory conditions of the skin, liver, arteries, and blood disorders.

You should never stop Imuran before consulting with your doctor. Sudden discontinuation may exacerbate symptoms. Your doctor may advise frequent blood tests and follow-up visits. After careful examination, they may gradually taper off the medication.
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Check our pricing section for Imuran 25mg Tablet price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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