Ciclosporin is used for the prevention of organ rejection in transplant patients, rheumatoid arthritis, psoriasis, bone marrow transplantation, nephrotic syndrome, uveitis, and Atopic dermatitis.
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Sandummun Neoral 50mg Capsule and its active ingredient, Cyclosporine. It's clear that this medication is used as an immunosuppressant primarily to prevent organ rejection in patients who have undergone solid organ transplantation. Here's a breakdown of the key points:
Avoid consumption of alcohol while taking Neoral 25mg Capsule as it might worsen your condition.
If you are taking Sandummun Neoral 25mg Capsule and are planning to become pregnant or are already pregnant, it is important to discuss this with your healthcare professional.
Neoral 25mg Capsule may pass through the breast milk. Therefore, it is not recommended for use in breastfeeding women. However, consult your doctor before taking it.
Do not drive or operate any heavy tools or machines if your ability is affected by Neoral 25mg Capsule.
Neoral 25mg Capsule is not recommended for use in patients with other kidney problems (except for nephrotic syndrome). Therefore, consult your doctor before taking it.
Neoral 25mg Capsule should be used with caution in patients with liver problems (including Hepatitis C infection). Therefore, consult your doctor before taking it.
Ciclosporin is an immunosuppressive agent that blocks the release of specific immune-triggering chemicals like T-cells, interleukins, and cytokines. By doing so, it suppresses the immune system, helping the body accept a newly transplanted organ. Additionally, it halts abnormal immune responses and prevents the body from attacking its own cells.
Ciclosporin serves several medical purposes, including:
These applications highlight the versatility of Cyclosporine in addressing various immune-related conditions and maintaining the health of different organs and systems in the body.
Cyclosporine forms a complex with cyclophilin. This complex goes on to inhibit calcineurin, a protein that typically triggers the activation of interleukin 2 transcription. Additionally, Cyclosporine hampers the production of lymphokines and the release of interleukins. In ophthalmic applications, the exact mechanism isn't fully understood. In the context of patients with reduced tear production due to ocular inflammation related to keratoconjunctivitis sicca, Cyclosporine emulsion is believed to function as a partial immunomodulator.
Dosages for Neoral 25mg Capsule in different medical conditions are as follows:
Solid Organ Transplantation:
Bone Marrow Transplantation:
Endogenous Uveitis:
Nephrotic Syndrome:
Rheumatoid Arthritis:
Psoriasis & Atopic Dermatitis:
Directions for Use:
Always follow your healthcare professional's instructions for accurate dosing and proper use of Neoral 25mg Capsule.
Drug-Drug Interactions: Cyclosporine can interact with various other medications, including:
Drug-Food Interaction: Avoid consuming grapefruit or grapefruit juice while taking Cyclosporine, as it can impact the effectiveness of the medication.
Drug-Disease Interactions: Cyclosporine might interact with certain disease conditions:
Neoral 25mg Capsule is not recommended for use in the following situations:
Pregnancy: There are no adequate and well-controlled studies in pregnant women and, therefore, Cyclosporine should not be used during pregnancy unless the potential benefit to the mother justifies the potential risk to the fetus.
Lactation: Cyclosporine passes into breast milk. Mothers receiving treatment with Cyclosporine should not breastfeed.
Store the Neoral 25mg Strip of 5 Capsules in a secure location inaccessible to toddlers or pets. Choose a well-ventilated room to prevent damage from heat and humidity. Refer to the label on the Neoral 25mg Strip of 5 Capsules for additional instructions.
Properly dispose of the medicine if it's no longer needed, ensuring it doesn't pose any risk to others. Disposal guidelines provided on the packaging should be followed.
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