Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Sizopin 100 helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, and behavior and enhances the quality of life.
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Sizopin 100 Tablet is an antipsychotic medication used to treat schizophrenia, a mental disorder that impairs thinking, emotions, and behavior. It alters brain chemicals to improve symptoms.
Common side effects of Sizopin 100 Tablet include agranulocytosis (a serious drop in white blood cells), drowsiness, tremors, sedation, insomnia, excessive salivation, weight gain, constipation, and irregular heartbeat. While many of these side effects may subside over time, never stop the medication without consulting a doctor. Seek immediate medical attention if you experience severe allergic reactions like skin rashes, swelling, or difficulty breathing.
Sizopin 100 Tablets can be taken with or without food, according to your doctor's instructions. Avoid alcohol and activities like driving or operating heavy machinery during treatment due to the risk of drowsiness. It is not recommended during breastfeeding, and you should consult your doctor if you are pregnant or planning to become pregnant. This medicine should be used cautiously in patients with heart, liver, or kidney issues and is not recommended for children under 16 years of age.
Consumption of alcohol during treatment with Sizopin 100 is not recommended due to an increased risk of severe side effects such as dizziness, confusion, impaired judgment, nausea, and vomiting. Additionally, alcohol may worsen concentration and coordination, so avoid activities like driving or operating machinery while on this medication.
Regarding pregnancy, this medication is generally avoided unless necessary. Your doctor will assess the risks and benefits before prescribing it.
Sizopin 100 is not recommended for use during breastfeeding.
Sizopin 100mg Tablet may cause side effects which could affect your ability to drive.
Sizopin 100 Tablet should be used cautiously, and a dose adjustment may be required depending on your health. It's important to consult your doctor for guidance.
Sizopin 100 Tablet should be used cautiously, and a dose adjustment may be required depending on your health. It's important to consult your doctor for guidance.
Sizopin 100 works by binding to certain receptors and inhibiting the release of the chemical substances that cause psychotic symptoms.
Common side effects include constipation, dizziness, drowsiness, headaches, and excessive salivation. Less frequent effects include dry mouth, abdominal discomfort, and unexpected weight gain.
Sizopin (Clozapine) is primarily used to treat schizophrenia in patients resistant to or intolerant of traditional antipsychotic medications. It is also indicated for managing psychosis related to Parkinson's disease.
Clozapine is an atypical antipsychotic that binds to dopamine receptors differently than typical antipsychotics, particularly with a high affinity for the D4 receptor. This selective binding reduces extrapyramidal side effects, as Clozapine is more active in limbic dopamine receptors than striatal ones. It also antagonizes adrenergic, cholinergic, histaminergic, and dopaminergic receptors.
Clozapine may interact with other CNS-active drugs and alcohol, potentially causing orthostatic hypotension. Its high protein-binding affinity may lead to displacement interactions with medications like warfarin and digoxin. Carbamazepine and Clozapine should not be used together, as Carbamazepine can lower Clozapine levels.
Clozapine is contraindicated in patients with severe cardiac disorders, renal impairment (creatinine clearance <10 mL/min), a history of neutropenia or agranulocytosis, bone marrow disorders, paralytic ileus, and severe CNS depression.
Clozapine has not been well-studied in pregnant women. It should be used in pregnancy only if necessary. Clozapine is excreted in animal milk, and breastfeeding should be avoided while on this medication.
Clozapine must be discontinued gradually to avoid withdrawal symptoms like psychosis and cholinergic rebound. Agranulocytosis is a serious side effect, so weekly WBC monitoring is required during the first six months, followed by biweekly checks. Clozapine can cause cognitive impairment, seizures, hyperglycemia, and other complications, particularly in the elderly and those with pre-existing conditions.
Store below 30°C, away from light and out of reach of children.