Generic Name: Prochlorperazine maleate 5mg
Manufacturer/Distributor: Pharmadesh Laboratories Ltd.
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Indications
Prochlorperazine Maleate is indicated-
Pharmacology
Dopamine and histamine antagonist prochlorperazine The blocking of histamine H and dopamine D2 neurotransmitter receptors in the chemoreceptor trigger zone and vomiting center is the mechanism of antiemetic activity. It also has a modest anticholinergic action and helps to prevent acid reflux by raising the tone of the lower esophageal sphincter.
Dosage & Administration
Antiemetic-
Children (not recommended in children <10 kg or <2 years):
Interaction
Alcohol, barbiturates, and other sedatives may have a more depressing effect on the CNS. Antacids, antiparkinson's medications, and lithium may interfere with Prochlorperazine absorption. Propanolol and phenobarbital plasma concentrations may be affected by this drug.
Contraindications
Allergic to prochlorperazine or any component of the preparation, severe CNS depression eats; should not be used in children under 2 years or less than 10 kg.
Side Effects
Drowsiness; spasms of the muscles of the chin, neck, and back; fine movements of the tongue like worms; rhythmic movements of the face, mouth, or jaw; speech slow or difficult; difficulty to swallow; restlessness and rhythm; tremors; drag the feet; acne; yellow skin or eyes
Pregnancy & Lactation
There is no evidence of adverse effects of the drug reported during pregnancy and breastfeeding.
Precautions & Warnings
You must be careful when performing tasks that require alertness, such as driving or using machinery. Drinking alcohol can cause extreme drowsiness. This drug can increase sensitivity to sunlight. Long-term exposure to the sun should be avoided. When someone is exposed to the sun, sunscreen and protective clothing should be worn. This medicine can reduce sweating and make you more prone to heat stroke.
Storage Conditions
Store below 30°C.Protect from light and moisture. Keep out of the reach of children.
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