Indications of Pevison 20mg
Econazole Nitrate & Triamcinolone Acetonide are indicated for the treatment of:
Eczematous Mycoses
Psoriasis
Tinea Pedis (Athlete’s foot)
Tinea Corporis (Ring worRingworm
Tinea Cruris (Jock itch)
Inflammatory Intertrigo
Diaper Dermatitis
Onychomycoses- for the treatment of onychomycoses, local therapy with Econazole/Triamcinolone cream, combined with an oral antimycotic, is recommended.
Dosage & Administration of Pevison 20mg
Adults: This cream should be applied sparingly to the skin lesion no more than 2 times daily, preferably once in the morning and once in the evening. This cream should not be applied with an occlusive dressing or too large areas of skin on the body. The duration of treatment with this cream should continue until the inflammatory symptoms subside but not longer than 2 weeks; after 2 weeks of therapy with this cream, continue therapy as needed with a preparation containing econazole or econazole nitrate alone.
Pediatric Use: Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing’s syndrome than mature patients because of a larger skin surface area to body weight. Caution should be exercised.
Side Effects
Rarely, transient local mild irritation, itching & redness may occur immediately after application. Econazole has a minimal allergenic effect and is well tolerated, even by delicate skin. Adrenal suppression on long-term contlong-topical steroid therapy may occur, particularly in infants or children, or when occlusive dressings are applied. It should be noted that an infant’s napkin may act as an occlusive dressing.
Pregnancy & Lactation
Pregnancy: Not the Econazole but the Triamcinolone Acetonide crosses the placenta and topical administration of corticosteroids during pregnancy can cause abnormalities of fetal development. The relevance of this finding to human beings has not been established. However, topical steroids in large amounts or for prolonged periods
should not be used during pregnancy.
Lactation: Negligible amount of econazole and to some extent Triamcinolone may be excreted in small amounts in breast milk. So this cream should not be prescribed to the lactating mother or if prescribed lactation should be withheld during treatment.
Precautions & Warnings
For external use only. This Cream is not for ophthalmic or oral use.
If a reaction suggesting hypersensitivity or chemical irritation should occur, the use of the medication should be discontinued.
Corticosteroids applied to the skin can be absorbed in sufficient amounts to produce systemic effects, including adrenal suppression. Systemic absorption may be increased by various factors such as application over a large skin surface area, application to damaged skin, an application under occlusive skin dressings, and prolonged duration of therapy.
Topical corticosteroids are associated with skin thinning and atrophy, striate, telangiectasias, and purpura.
Topical corticosteroids may lead to an increased risk of dermatological superinfection or opportunistic infection.
Children: Increased caution is required when treating children. Compared to adults, the nature of a child’s skin and the larger skin surface area relative to body weight may lead to increased absorption of the corticosteroid via the child’s skin. This cream should be used in children only for short periods of time (less than 2 weeks) and on small areas (less than 10% of body surface area).
Visual disturbance may be associated with systemic and topical corticosteroid use. If a patient presents with symptoms such as blurred vision or other visual disturbances, the patient should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma, or rare diseases such as central serous chorioretinopathy (CSCR).
Overdose Effects
This Cream is for cutaneous application only. Corticosteroids applied to the skin, including triamcinolone, can be absorbed in sufficient amounts to produce systemic effects. In the event of accidental ingestion, treat symptomatically. If this cream is accidentally applied to the eyes, wash with clean water or saline and seek medical attention if symptoms persist.
Storage Conditions
Store in a cool (below 30°C) and dry place, away from light. Keep out of the reach of children.
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