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Generic Name: Dioxybenzone 0.3% + Hydroquinone 0.4% + Octyldimet p-aminobenzoate 0.8% + Oxybenzone 0.2%
Company Name: Incepta Pharmaceuticals Ltd
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✅ Description:
Indications
Melasma can be treated with Spotclen Cream. It is a skin-lightening medication that makes darkened skin spots and patches lighter (hyperpigmentation). It lessens the skin's melanin content, a pigment that darkens the skin. It aids in the skin's reversible depigmentation.
Pharmacology
A topical depigmenting medication called hydroquinone prevents the enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine and suppresses the metabolic activities of melanocytes, leading to reversible skin depigmentation.
Dosage & Administration
- Every day, at least 30 minutes before going to bed, slather a thin layer of Hydroquinone Cream on the affected area.
- Use a gentle cleanser to gently wash the face and neck.
- Rinse the skin, then pat it dry.
- Apply Hydroquinone Cream to the hyperpigmented melasma lesions and the half-inch of surrounding normal-looking skin.
- Gently and uniformly massage the skin.
- When control is attained, therapy should be stopped.
- Use SPF 30 sunscreen and wear protective clothing during the day.
- Avoid being in the sun.
- During the day, patients may apply moisturizers and/or cosmetics.
- Hydroquinone Cream should only be applied topically.
- It is not intended for intravaginal, ophthalmic, or oral use.
Contraindications
Hydroquinone is contraindicated to patients with prior history of hypersensitivity or allergic reaction to hydroquinone or other ingredients in the preparation.
Side Effect
There have been no reports of systemic side effects. Hypersensitivity (localized contact dermatitis) may develop from time to time, in which case the drug should be stopped.
Pregnancy & Lactation
Pregnancy Classification C. Either animal research has indicated negative effects on the fetus (teratogenic, embryocidal, or other) and no controlled studies in women have been conducted, or studies in women and animals are not accessible. Only if the possible benefit outweighs the risk to the fetus should drugs be administered.
It is unknown if topical hydroquinone is absorbed or eliminated in human milk during lactation. When a nursing mother uses topical hydroquinone, caution is suggested.
Precautions & Warnings
- A skin-whitening agent called hydroquinone can have undesirable cosmetic effects if it is not used as directed.
- Before writing prescriptions or handing out medications, doctors must be familiar with the information in this manual.
- Before use, test your skin's sensitivity.
- Within 24 hours, apply a small amount to an entire piece of skin to verify.
- Mild redness is not a contraindication, but further treatment is not advised if itching, blistering, or excessive inflammation develops.
- After two months of treatment, if no whitening or lightening effect has been seen, the medication should be stopped.
- Avoid making eye and lip contact. Skin that has been cut or bruised shouldn't be treated with hydroquinone.
Storage Conditions
Store between 20-25° C. Protects from light.
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