Unicort - ePharma
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Unicort 0.01% Cream

Generic: Hydrocortisone 1%

Type: Cream

Pack Size: 1 Pc

Not Available

Cream Manufacturer/Distributor: G. A. Company Ltd. Generic Name: Hydrocortisone 1% Cream

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Discount Price: ৳ 15
MRP: ৳ 16.05 4% Off

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✅ Description:

Indications

The anti-inflammatory activity of hydrocortisone acetate is its main therapeutic property. It also has immunosuppressive and anti-mitotic effects. Hydrocortisone acetate is indicated for:

Primary irritant dermatitis

Atopic contact dermatitis

Eczema: atopic, neonatal, discoid, blood stasis

Seborrheic dermatitis

Lichen and anal pruritus

Scales flexible candle

Skin irritation, itching and eg insect bites, heat burns, sunburn, etc.

 

Pharmacology

Hydrocortisone binds to intracellular glucocorticoid receptors. After binding to the receptor, the newly formed receptor and receptor complex translocates to the cell nucleus, where it binds to several glucocorticoid response elements (GRE) in the promoter region of the target gene. The DNA binding receptor then interacts with basic transcription factors, causing an increase in the expression of specific target genes. The anti-inflammatory effects of corticosteroids are believed to be related to lipocortins, the inhibitory protein of phospholipase A2, by inhibiting arachidonic acid, which controls the biosynthesis of prostaglandins and leukotrienes. More specifically, glucocorticoids induce the synthesis of lipocortin1 (annexin1), which then binds to cell membranes preventing phospholipase A2 from coming into contact with its substrate, arachidonic acid. This leads to reduced eicosanoid production. The expression of cyclooxygenase (both COX1 and COX2) was also suppressed, increasing the effect. In other words, the two main inflammatory products, Prostaglandins and Leukotrienes, are inhibited by the effects of Glucocorticoids. Glucocorticoids also stimulate lipocortin1 to escape to the extracellular space, where it binds to leukocyte membrane receptors and inhibits various inflammatory phenomena: epithelial adhesion, migration, thermoregulation, phagocytosis, respiration, and release of various inflammatory mediators (lysosomal enzymes, cytokines, tissue plasminogen activators, chemokines, etc.) In addition, the immune system is suppressed by corticosteroids due to decreased function of the lymphatic system, decreased levels of immunoglobulins and complement, precipitation of lymphopenia, and interference with antigen-antibody binding.

Dosage & Administration

Hydrocortisone Acetate should be applied in a small quantity to the affected area 2 or 3 times daily.

Contraindications

Infections: bacterial, viral, fungal.

Skin ulcers.

Hypersensitivity to the preparation.

 

Side Effects

Hydrocortisone Acetate 1% cream is usually well-tolerated, but if signs of hypersensitivity appear, the application should be stopped.

Pregnancy & Lactation

There is insufficient evidence for safety during pregnancy in humans. Generalized use of topical corticosteroids during pregnancy is recommended to be discouraged. It is very unlikely that sufficiently high blood concentrations of hydrocortisone during topical treatment will be reached in breast milk.

Precautions & Warnings

In infants and children, long-term continuous topical therapy should be avoided if possible, as adrenal suppression may occur. As with all corticosteroids, prolonged application to the face is not desirable.

Storage Conditions

Store in a cool and dry place, away from light. Keep out of reach of children.

Offer

Relevant Products / প্রাসঙ্গিক পণ্য

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Check our pricing section for Unicort 0.01% Cream price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

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