Fevigra 100mg Tablet 10pcs

✔️ Quick Suggestions of Fevigra 100

• Take Fevigra 100 exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
• Take Fevigra 100 only at bedtime.
• Avoid drinking alcohol for at least 2 hours before taking Fevigra 100 and until the next day. Alcohol may cause you to have dangerously low blood pressure if taken with flibanserin.
• Skip your bedtime dose if you have consumed alcohol less than 2 hours earlier.
• Flibanserin can lower your blood pressure, which can make you dizzy. If you feel light-headed after taking this medicine, lie down if you are not already in bed.
• It may take up to 8 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

✔️ Uses of Fevigra 100

Treats decreased sexual desire in women

✔️ Side Effects of Fevigra 100

Common side effects (>10%) include dizziness, somnolence, and nausea. Other side effects (1-10%) may include fatigue, insomnia, dry mouth, anxiety, constipation, abdominal pain, metrorrhagia, rash, sedation, and vertigo.

✔️ How does Fevigra 100 work?

Flibanserin acts as a postsynaptic serotonin-1A (5HT-1A) receptor agonist and 5HT-2A receptor antagonist. It also exhibits moderate antagonist activities at the 5-HT2B, 5-HT2C, and dopamine D4 receptors. The mechanism of action in HSDD is not fully understood but may involve restoring prefrontal cortex control over the brain's motivation/reward structures, thereby enabling sexual desire to manifest.

✔️ Pharmacology:

Flibanserin, the active ingredient in Fevigra, has a high affinity for serotonin receptors in the brain, acting as an agonist on 5-HT1A and an antagonist on 5-HT2A receptors. It may also moderately antagonize D4 (dopamine) receptors and 5-HT2B and 5-HT2C receptors. Its action on neurotransmitter receptors may contribute to a reduction in serotonin levels and an increase in dopamine and norepinephrine levels, all of which may play a part in reward processing.

✔️ Adult Dose:

For hypoactive sexual desire disorder, the recommended dose is 100 mg orally once daily at bedtime. It's dosed at bedtime to mitigate risks of hypotension, syncope, accidental injury, and CNS depression. Treatment should be discontinued after 8 weeks if no improvement is observed.

✔️ Interaction:

Fevigra may interact with oral contraceptives and other weak CYP3A4 inhibitors, strong CYP2C19 inhibitors, CYP3A4 inducers, and digoxin.

✔️ Contraindications:

Fevigra is contraindicated in patients using alcohol, concomitant use with moderate or strong CYP3A4 inhibitors, and in patients with hepatic impairment.

✔️ Pregnancy & Lactation:

There are no studies of Fevigra in pregnant women. It's excreted in rat milk, and its presence in human milk and effects on the breastfed infant are unknown. Breastfeeding is not recommended during treatment with Fevigra.

✔️ Precautions & Warnings:

Patients experiencing pre-syncope should immediately lie supine and seek medical help if symptoms persist. CNS depression can occur with Fevigra alone and may be exacerbated by other CNS depressants. Patients should avoid activities requiring full alertness until they know how Fevigra affects them.

✔️ Storage Conditions:

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.