Folison 5mg Tablet

✔️ Uses of Folison Tablet

• To treat Pernicious Anemia
• Nutritional supplement
• Folic Acid Deficiency
• Synthesis and Repair of DNA and Other Genetic Material

✔️ How to use Folison Tablet

• Take this medicine in the dose and duration as advised by your doctor.
• Swallow it as a whole.
• Do not chew, crush or break it.
• Folison tablets may be taken with or without food, but it is better to take them at a fixed time.

✔️ How Folison Tablet works

Folic acid: Required for nucleoprotein synthesis and normal erythropoiesis; dihydrofolate reductase converts folic acid in the liver and plasma to its metabolically active form, tetrahydrofolic acid; prevents neural tube defects in women of childbearing potential; higher doses required during pregnancy.

✔️ Side effects of Folison Tablet

Folic acid is well tolerated by the majority of people. It's possible that you'll experience gastrointestinal issues. Only a few cases of hypersensitivity reactions have been observed.

✔️ Quick Suggestions:

• Use  Folison only as directed by your doctor. Use it in smaller doses and for no longer than suggested. Stick to the instructions on your medicine package.
• Oral Folison is given by mouth.
• With a full glass of water, takeFolison pills.
• To ensure that you get the greatest outcomes from this medicine, your doctor may sometimes adjust your dose.

✔️ Indications

• To make up for a folic acid deficiency, folic acid is prescribed.
• A type of anemia known as megaloblastic anemia occurs when the red blood cells
• Anemia is brought on by a diet low in iron, pregnancy, childbirth, or early childhood.

✔️ Pharmacology

Due to its biochemical inactivity, dihydrofolate reductase transforms folic acid into tetrahydrofolic acid and methyltetrahydrofolate (DHFR). These folic acid congeners are transported by endocytosis throughout cells, where they are necessary for maintaining healthy erythropoiesis, producing purine and thymidylate nucleic acids, converting amino acids, methylating tRNA, and producing and using formate. By remethylating homocysteine to methionine via methionine synthetase, which uses vitamin B12 as a cofactor, folic acid can reduce high homocysteine levels.

✔️ Dosage and Administration of Folison

Adults-

• Initially: 5 mg daily for 4 months.
• maintenance: 5 mg every 1-7 days depending on the underlying disease.

Children-

It is likely safe for children to take folic acid by mouth in the recommended amounts for their age. But children should avoid taking folic acid in doses that are higher than the daily upper limits. 

• Up to 1 year: 500 mcg/kg daily.
• 1-3 years of age: 300 mcg
• 4-8 years of age: 400 mcg
• 9-13 years of age: 600 mcg
• 14-18 years of age: 800 mcg

Take Folison as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Folisoncan be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

✔️ Interaction

There have been no reports of any.

✔️ Contraindications

Folic acid is contraindicated in patients who have shown previous intolerance to the drug.

✔️ Pregnancy & Lactation

There are no recognized specific precautions.

✔️ Precautions & Warnings

• In patients with folate-dependent tumors, it should be used with caution.
• For the treatment of undetected megaloblastic anemia, it should never be given alone or in combination with insufficient levels of vitamin B12.
• Although folic acid can cause a hematopoietic response in patients with megaloblastic anemia caused by vitamin B12 deficiency, it should not be used alone in vitamin B12 insufficiency since it can cause subacute mixed cord degeneration.
• Before starting long-term folate therapy, a cobalamin absorption test should be performed in elderly adults.
• Short courses of folate had no negative effects.

✔️ Storage Conditions

Store at or below 30°C in a dry, dark area. Keep out of children's reach.