Orsema 0.50mg Subcutaneous Injection | Price | Incepta | ePharma
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Orsema 0.50mg Subcutaneous Injection

Generic: Semaglutide

Type: Injection

Pack Size: 1 Pc

Semaglutide addresses weight loss as an adjunct to lifestyle changes, but diet and exercise remain fundamental in obesity management.


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Discount Price: ৳ 558
MRP: ৳ 600 7% Off

⪼ Save  ৳: 42  in this Product


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✅ Description:

Semaglutide, is an anti-diabetic medication used for treating type 2 diabetes mellitus.

Semaglutide: GLP-1 receptor agonist (anti-diabetic agent), enhances glycemic control through insulin secretion, slowing gastric emptying, and reducing postprandial glucagon secretion.

  • Treatment of type 2 diabetes in adults (18 years and older)
  • When diet and exercise alone are insufficient
  • When other diabetes medications are ineffective or cannot be used
  • Allergic reactions: Do not take if allergic to any components.
  • Eye problems: Inform the doctor if any eye issues arise.
  • Stomach pain: Seek immediate medical attention for significant and ongoing stomach pain, as it could indicate acute pancreatitis.
  • Alcohol: Avoid alcohol to reduce the risk of lactic acidosis or other complications.
  • Pregnancy and breast-feeding: Not recommended; consult a doctor if pregnant or nursing.
  • Children: Not recommended for those below 18 years.
  • Driving: Be cautious as low or high blood sugar may affect driving ability.
  • Report persistent or worsening side effects to the doctor.
  • Modification of treatment may be necessary if pregnancy occurs.

Safety Advices


Alcohol
UNSAFE

It is advised to avoid alcohol intake, as it may worsen side effects like lactic acidosis and increase the risk of developing low blood sugar levels.


Pregnancy
CONSULT YOUR DOCTOR

Semaglutide is not recommended during pregnancy, as its effects on the unborn baby are unknown. Discuss any concerns with your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

Semaglutide should not be used if you are breastfeeding, as it is unknown whether it passes into breast milk. Discuss any concerns with your doctor.


Driving
CAUTION

Exercise caution while driving. If your blood sugar is too low or too high, it may affect your driving ability. Do not drive if these symptoms appear.


Kidney
CONSULT YOUR DOCTOR

Exercise caution in people with kidney impairment. Inform your doctor about any history of kidney impairment/disorder. The prescription will be considered if the benefits outweigh the risks.


Liver
CONSULT YOUR DOCTOR

Limited information is available on the use of Semaglutide in patients with liver impairment. Consult your doctor if you have concerns. The prescription will be considered if the benefits outweigh the risks.

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✔️ Uses of Orsema 0.50mg Subcutaneous Injection

Type 2 Diabetes Mellitus

✔️ How does Orsema 0.50mg Subcutaneous Injection work?
  • Acts on brain areas suppressing appetite and inducing a feeling of fullness.
  • When combined with diet and exercise, it leads to significant weight loss.
✔️ Side Effects of Orsema 0.50mg Subcutaneous Injection
  • Generally mild.
  • Common side effects include dizziness, fatigue, gastrointestinal issues (diarrhea, constipation, gassiness), headache, and stomach issues (nausea, vomiting, pain, distension).
✔️ Quick Suggestions:
  • Take Semaglutide as advised by your physician. It should be taken on an empty stomach. After taking Semaglutide wait at least 30 minutes before having your first meal or drink of the day or taking other oral medicines. Do not stop using this medicine without telling your doctor. Otherwise, your blood sugar levels may raise
  • Stay hydrated by drinking plenty of water throughout the day
  • Attend regular health checkups while taking this medicine
  • Inform your healthcare provider about all the medications, supplements, and herbal products you are using, as Semaglutide can interact with certain drugs
  • Semaglutide is not recommended for use in pregnant or breastfeeding women
✔️ Indication

Type 2 Diabetes Mellitus (T2DM): Adjunct to diet and exercise for improving glycemic control in adults.

✔️ Pharmacology

GLP-1 Agonist:

  • Enhances glucose-dependent insulin secretion.
  • Suppresses inappropriately elevated glucagon secretion.
  • Slows gastric emptying.
✔️ Dosage & Administration:

Adult Dose:

Subcutaneous Administration:

  • 0.25 mg SC: Once weekly for 4 weeks initially.
  • Dose Escalation:
    • Increase to 0.5 mg SC once weekly.
    • If glycemic control is not achieved, can be further increased to 1 mg SC once weekly.
  • The initial 0.25-mg dose is for treatment initiation and is not effective for glycemic control.

Child Dose:

  • <18 years: Safety and efficacy not established.

Renal Dose:

  • Renal impairment: No dosage adjustment is required.

Administration:

  • SC Administration:
    • Administer to the abdomen, thigh, or upper arm.
    • Once weekly, on the same day each week, at any time of the day, with or without meals.
    • Change the injection site weekly when injecting in the same body region.
✔️ Interaction
  • Insulin secretagogues or insulin may increase the risk of hypoglycemia.
  • Caution with oral medications due to delayed gastric emptying.
✔️ Contraindications

Avoid individuals with:

  • History of medullary thyroid cancer.
  • History of gallbladder disease.
  • History of pancreatitis.
  • Multiple endocrine neoplasia syndrome type 2 (MEN2).
✔️ Pregnancy & Lactation
  • Pregnancy:
    • Limited data; potential risks to the fetus.
    • Use during pregnancy if benefits justify potential risks.
    • Discontinue treatment at least 2 months before a planned pregnancy.
  • Lactation:
    • No data on the presence of semaglutide in human milk.
    • Detected in rat milk at lower levels than in maternal plasma.
✔️ Precautions & Warnings
  • Based on animal studies, semaglutide may cause thyroid C-cell tumors, including MTC.
  • Monitor for signs and symptoms of pancreatitis (persistent severe abdominal pain, possibly radiating to the back, with or without vomiting).
  • Patients with a history of diabetic retinopathy may have an increased risk for complications.
  • Semaglutide pens must not be shared between patients.
  • Monitor renal function in patients reporting severe adverse gastrointestinal reactions.
✔️ Storage Conditions
  • Store your Orsema in the refrigerator at 2°C to 8°C (36°F to 46°F).
  • After the first use of Orsema, the pen can be stored for 56 days in a refrigerator (2°C to 8°C).
  • Do not freeze Orsema. Do not use it if it has been frozen.
  • Unused Orsema cartridges may be used until the expiration date printed on the label, as long as they are kept in the refrigerator (2°C to 8°C).
  • Keep Orsema away from heat.
  • Store Orsema away from direct light.
  • Keep the pen cap on when Orsema is not in use.
Frequently Asked Questions (FAQ)

Semaglutide injection is utilized in the treatment of type 2 diabetes. It is administered in conjunction with a balanced diet and regular exercise to manage blood sugar levels. Additionally, this medication is prescribed to reduce the risk of heart attack, stroke, or mortality in individuals with type 2 diabetes who also have heart or blood vessel disease.

Yes

Weight loss outcomes with Semaglutide can vary among individuals, but based on data from randomized controlled trials, it's suggested that one can anticipate losing up to 5% of their weight within a month of using semaglutide. After two months of consistent use, the weight loss may increase, with an expected loss of up to 8%. It's important to note that individual responses to the medication can differ, and lifestyle factors such as diet and exercise play a significant role in achieving weight loss goals.

When individuals stop taking Orsema 0.50 or other GLP-1 agonists, it's indeed possible to experience changes in weight, but weight gain is not a guaranteed side effect. The efficacy of these medications in promoting weight loss is often linked to their impact on appetite regulation and metabolism. Semaglutide, like other GLP-1 agonists, has been found to influence appetite and lead to weight loss when used consistently. However, the effects on weight can vary from person to person. Some individuals may experience significant weight loss, while others may see more modest changes. If someone discontinues the use of Semaglutide, their body may undergo adjustments, and there is a possibility of some weight regain. The key to sustaining weight loss often involves adopting and maintaining healthy lifestyle habits, including a balanced diet and regular physical activity.

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Check our pricing section for Orsema 0.50mg Subcutaneous Injection price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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