Ryzodeg Flextouch Pre Filled Pen | 100IU | ePharma
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Ryzodeg Flextouch Pre Filled Pen

Generic: Insulin Degludec + Insulin Aspart

Type: Injection

Pack Size: 1 Pc

Ryzodeg Flextouch Pre-Filled Pen is used to improve glycemic control in patients with diabetes mellitus (both Type I and Type II)


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Discount Price: ৳ 1800.25
MRP: ৳ 1895 5% Off

⪼ Save  ৳: 94.75  in this Product


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✅ Description:

Insulin Aspart (30 International units) + Insulin Degludec (70 International units) in Ryzodeg Flex Touch Pre-Filled Pen is a combination of fast-acting and long-acting analogs of insulin used for treating diabetes mellitus. Insulin is a hormone produced naturally by the pancreas that helps in utilizing glucose for energy production. However, patients with diabetes mellitus may have insufficient insulin production or their bodies may be unable to effectively use insulin, leading to elevated blood glucose levels.

Ryzodeg Flex Touch helps in the utilization of glucose and controlling blood glucose levels in such patients by providing both fast-acting and long-acting insulin analogs. The fast-acting insulin aspart helps in quickly lowering blood glucose levels after meals, while the long-acting insulin degludec provides a steady level of insulin throughout the day, helping to maintain blood glucose levels between meals and overnight.

Patients using Ryzodeg Flex Touch Pre-Filled Pen are advised to follow a strict exercise and diet regimen prescribed by their healthcare provider to achieve the best possible effect in controlling their blood glucose levels. It's important for patients to adhere to their prescribed treatment plan and regularly monitor their blood glucose levels to ensure optimal management of their diabetes.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while taking  Ryzodeg Flextouch Pre-Filled Pen as it could aggravate your existing disease condition.


Pregnancy
CONSULT YOUR DOCTOR

 Ryzodeg Flextouch Pre-Filled Pen 100IU can be used during pregnancy if prescribed by the physician. However, consult your doctor before administration


Breastfeeding
CONSULT YOUR DOCTOR

Ryzodeg Flextouch Pre-Filled Pen 100IU should be used with caution in breastfeeding women. Therefore, consult your doctor before administration.


Driving
CAUTION

Do not drive or operate any heavy tools or machines if your ability is affected by  Ryzodeg Flextouch Pre-Filled Pen 100IU.


Kidney
CAUTION

Ryzodeg Flextouch Pre-Filled Pen should be used with caution in patients with kidney problems. Therefore, consult your doctor before administration.


Liver
CAUTION

Ryzodeg Flextouch Pre-Filled Pen should be used with caution in patients with liver problems. Therefore, consult your doctor before administration.

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✔️ Uses of Ryzodeg Flextouch Pre-Filled Pen
  • Type I Diabetes mellitus
  • Type II Diabetes Mellitus
✔️ How does Ryzodeg Flextouch Pre-Filled Pen work?

This medicine is a replacement insulin that works by enhancing the glucose uptake for energy production. This helps in controlling the blood glucose levels.

✔️ Side Effects of Ryzodeg Flextouch Pre-Filled Pen

Injection site reactions, lipodystrophy, lumps under the skin, weight gain, swelling of body parts, and hypoglycemia are common side effects of Ryzodeg Flextouch Pre-Filled Pen. However, if you experience any of the following severe side effects, consult your doctor immediately:

  1. Allergic reaction: This may include generalized skin rash with itching, sweating, swelling of layers under the skin, difficulties in breathing, palpitation, vomiting, stomach upset, reduction in blood pressure, and fainting.
  2. Signs of severe hypoglycemia: These may include cold sweats, cool pale skin, headache, rapid heartbeat, nausea, increased hunger, temporary vision changes, drowsiness, tiredness and weakness, nervousness or tremors, anxiety, confusion, and difficulty concentrating.
  3. Signs of heart failure: These may include shortness of breath, edema, and rapid weight gain.

If you experience any of these severe side effects, it is important to seek immediate medical attention.

✔️ Quick Suggestions:
  • Ryzodeg Flextouch Pre-Filled Pen 100IU should not be mixed with any other insulins before use.
  • Do not stop therapy with Ryzodeg Flextouch Pre-Filled Pen 100IU without consulting your doctor.
  • Your doctor will determine the correct dose and frequency of administration based on factors such as age, body weight, and health condition.
✔️ Indication of Ryzodeg Flextouch Pre-Filled Pen

Insulin degludec and insulin aspart are both analogs of human insulin, with insulin degludec being a long-acting insulin analog and insulin aspart being a rapid-acting insulin analog. They are indicated to improve glycemic control in patients aged 1 year and older with diabetes mellitus.

✔️ Pharmacology

Both insulin degludec and insulin aspart bind specifically to the human insulin receptor, resulting in the same pharmacological effects as human insulin. These effects primarily involve the regulation of glucose levels in the blood.

The blood glucose-lowering effect of insulin occurs through several mechanisms. First, insulin facilitates the uptake of glucose by cells, particularly muscle and fat cells, which allows glucose to be utilized for energy production. Additionally, insulin inhibits the release of glucose from the liver into the bloodstream, further contributing to the reduction of blood glucose levels.

By mimicking the action of endogenous insulin, insulin degludec and insulin aspart help to regulate blood glucose levels and improve glycemic control in patients with diabetes mellitus.

✔️ Dosage & Administration of Ryzodeg Flextouch Pre-Filled Pen

The dosage and administration instructions for the Ryzodeg Flextouch Pre-Filled Pen are as follows:

Dosage:

  • Ryzodeg Flextouch Pre-Filled Pen 100IU is a soluble insulin product containing both basal insulin degludec and rapid-acting prandial insulin aspart.
  • The dosage should be tailored according to the individual patient's needs.
  • Dosage adjustments are primarily recommended based on fasting plasma glucose measurements.
  • For patients with type 2 diabetes mellitus, the recommended total daily starting dose is 10 units with meal(s), followed by individual dosage adjustments.
  • For patients with type 1 diabetes mellitus, the recommended starting dose is 60-70% of the total daily insulin requirements. This should be used once daily at meal-time in combination.

Administration:

  • Use Ryzodeg Flextouch Pre-Filled Pen 100IU under careful medical supervision.
  • Inject Ryzodeg Flextouch Pre-Filled Pen 100IU subcutaneously into your thighs, buttocks, upper arm, or abdomen.
  • Do not administer this medicine into the vein or muscle directly.
  • Administer at least 10 minutes before meals.
  • Consume a meal or snack containing carbohydrates within 20 minutes of the injection to avoid low blood sugar.
  • Before administration, roll the vial/cartridge between your hands until the liquid becomes uniformly white and cloudy.
  • Keep the needle under the skin for at least 6 seconds while injecting to ensure the entire dose is administered.
  • Visually inspect the cartridge/vial for any visible particulate matter and discoloration before administration.
  • Discard the needle and syringe after use, and do not share your needles with others to prevent the risk of transmission of infections.
  • Avoid repeatedly injecting the medicine at the same site to prevent skin damage. Rotate the injection site as instructed by your doctor.
✔️ Interaction

It's crucial to be aware of potential interactions between medications, as well as between medications and other substances like alcohol. Here's a summary of the interactions associated with Ryzodeg FlexTouch Pre-Filled Pen:

Interaction with Alcohol:

  • Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of both hypoglycemia (low blood glucose levels) and hyperglycemia (high blood glucose levels).
  • Depending on the quantity and frequency of alcohol consumption, this may lead to severe side effects such as dizziness, drowsiness, increased thirst, increased hunger, mood changes, and extreme fatigue.

Interaction with Medicine:

  • Corticosteroids
  • Beta blockers
  • ACE inhibitors
  • Gatifloxacin
  • Fluoroquinolones
  • Aspirin

Disease Interactions:

  • Kidney Disease: Caution is advised in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of blood glucose levels is recommended, and appropriate dose adjustments may be necessary.
  • Hypokalemia: Patients at an increased risk of developing hypokalemia (decreased blood potassium levels) or those suffering from hypokalemia should use this medicine with caution, as it may worsen their condition. Appropriate corrective measures, dose adjustments, or alternative medications may be required.
  • Liver Disease: Caution is advised in patients with a history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of blood glucose levels is recommended, and appropriate dose adjustments may be necessary.
✔️ Contraindications

Hypersensitivity to the active substances or any of the excipients.

✔️ Pregnancy & Lactation

Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant the use of the drug in pregnant women despite potential risks There are no data on the presence of insulin degludec in human milk, the effects on the breastfed infant, or the effect on milk production. Insulin degludec is present in rat milk. One small published study reported that exogenous insulin, including insulin aspart, was present in human milk. However, there is insufficient information to determine the effects of insulin aspart on the breastfed infant and no available information on the effects of insulin aspart on milk production. 

✔️ Precautions & Warnings
  • The omission of a meal or unplanned strenuous physical exercise may lead to hypoglycemia. This can also occur if the insulin dose is too high relative to the insulin requirement. Patients with concomitant illnesses, especially infections and fever, typically experience an increased insulin requirement. Patients with kidney, liver, adrenal, pituitary, or thyroid gland diseases may require adjustments in insulin dose to manage hypoglycemia.
  • Administration of rapid-acting insulin is recommended for severe hyperglycemia. Inadequate dosing or discontinuation of insulin treatment in patients who require it may lead to hyperglycemia and potentially diabetic ketoacidosis. Concomitant illnesses, particularly infections, can also lead to hyperglycemia by increasing insulin requirements.
  • Abrupt improvement in glycemic control with intensified insulin therapy may temporarily worsen diabetic retinopathy. However, long-term improved glycemic control reduces the risk of progression of diabetic retinopathy.
  • Patients must always check the insulin label before each injection to avoid accidental mix-ups between Ryzodeg FlexTouch Pre-Filled Pen and other insulin products.
  • Ryzodeg can be used in older patients. However, glucose monitoring should be intensified, and insulin doses adjusted on an individual basis.
  • Ryzodeg has been administered to children and adolescents up to 18 years of age for the investigation of pharmacokinetic properties. Safety and efficacy have not been fully investigated in children and adolescents. Therefore, caution should be exercised when using this medication in pediatric patients.
✔️ Storage Conditions
  • Keep out of reach of children
  • Store the unopened pack in the refrigerator at 2-8°C. Do not freeze
  • During use or when carried as a spare, keep it at room temperature
  • Always place the vial/cartridge in the outer carton to protect it from light
  • Do not use the medicine after 28 days of opening
Frequently Asked Questions (FAQ)

A: Yes. An unopened pack must be stored in the refrigerator (2-8°C). During use or while carrying it as a spare, keep it at room temperature to ensure uniform resuspension.

A: Yes. Ryzodeg Flextouch Pre-Filled Pen 100IU may cause weight gain in some individuals, although not everybody gets them. If you are worried about excessive weight gain, eat a healthy low-carb/fat diet with regular physical activity. Consult your doctor if the symptoms do not improve.

A: It is not advisable to take medicines to control blood pressure while taking Ryzodeg Flextouch Pre-Filled Pen 100IU without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive medications along with Ryzodeg Flextouch Pre-Filled Pen 100IU as they have known interactions with Ryzodeg Flextouch Pre-Filled Pen 100IU.

A: No. You should not stop therapy with Ryzodeg Flextouch Pre Filled Pen 100IU without consulting your doctor because it may lead to a reversal of symptoms. If you feel better after using Ryzodeg Flextouch Pre Filled Pen 100IU, consult your doctor for advice.

A: Yes. Ryzodeg Flextouch Pre-Filled Pen 100IU can be used during pregnancy if prescribed by the physician. Therefore, consult your doctor before administration.

A: No, taking a higher dose of Ryzodeg Flextouch Pre Filled Pen 100IU will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

A: No. Ryzodeg Flextouch Pre-Filled Pen 100IU is meant for subcutaneous use only (i.e., thighs, buttocks, abdomen, or upper arms). It should not be directly injected into the vein or muscle as it may cause severe hypoglycemia.

A: The most common side effects of injecting RYZODEG FLEX TOUCH PEN 100IU are low blood sugar levels, pain, redness, itching, swelling or thickening at the injection site, lump formation under the skin, and swelling of body parts. Consult your doctor if any of these side effects trouble you.

A: Ryzodeg Flextouch Pre-Filled Pen 100IU is used in the management of diabetes mellitus (both type I and II).

Should I inject it only at the same site every day? A: The best place for injecting this medicine is the front of your thighs, buttocks, abdomen, or upper arms. Insulin works more quickly if injected into the waist (abdomen). Do not repeatedly inject the medicine at the same site. Instead, rotate the injection sites within the same area to avoid the risk of developing lumps or skin pitting.

A: Ryzodeg Flextouch Pre Filled Pen 100IU is a fast-acting medicine where that begins to lower blood sugar levels about 30 minutes post-administration, and its effect lasts for about 24 hours.

No. Do not mix Ryzodeg Flextouch Pre-Filled Pen 100IU with other insulins. Always consult your doctor before mixing insulins.
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Check our pricing section for Ryzodeg Flextouch Pre Filled Pen price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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