Adlinameg 2.5/500mg Tablet is used to control high blood sugar in patients who have type 2 diabetes mellitus, along with a healthy diet and regular exercise.
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Linagliptin + Metformin Hydrochloride is a combination medication containing Linagliptin (a DPP-4 inhibitor) and Metformin (a Biguanide), belonging to the anti-diabetic class. In type 2 diabetes, the body either doesn't produce enough insulin or becomes resistant to its effects. This medication addresses these issues.
Linagliptin, a DPP-4 inhibitor, blocks an enzyme that breaks down incretin hormones, which regulate insulin production. It also reduces unnecessary sugar production by the liver. Metformin, on the other hand, lowers glucose production in the liver, slows sugar absorption from the intestines, and enhances insulin sensitivity. Together, they prevent excessive blood sugar levels after meals.
Take Linagliptin + Metformin Hydrochloride with food to avoid stomach upset. Consistency in timing is important. Dosage adjustments should be based on your doctor's guidance, as they may change according to your condition. Common side effects include hypoglycemia (low blood sugar) symptoms like dizziness and sweating. To prevent this, avoid skipping meals and keep sugar handy. Other side effects include taste changes, nausea, diarrhea, stomach pain, headache, and respiratory symptoms.
Do not discontinue Linagliptin + Metformin Hydrochloride abruptly, even if you feel better, as blood sugar levels fluctuate. Stopping suddenly can raise the risk of complications like eyesight loss, kidney problems, and nerve damage. This medication is not suitable for type 1 diabetes or severe kidney/liver disease. Inform your doctor about heart disease, pregnancy plans, or breastfeeding.
Avoid consumption of alcohol while taking Adlinameg 2.5/500mg Tablet as it may increase the risk of unwanted side effects.
Adlinameg 2.5/500mg Tablet is not recommended for use in pregnant women owing to the risk of abnormalities in the fetus. Alternate means of blood sugar control like insulin therapy should be considered during pregnancy.
Adlinameg 2.5/500mg Tablet is not advised for breastfeeding women due to potential risks to the baby. If blood sugar control is needed, alternatives like insulin therapy should be explored. If absolutely necessary, taking this medication may require discontinuing breastfeeding.
Adlinameg 2.5/500mg Tablet generally doesn't impair driving. If you encounter low blood sugar symptoms while driving, like dizziness or sweating, stop driving and consume sugar/juice. Keep sugar, juice, or chocolate in the car, and avoid sugar-free options during such episodes.
Adlinameg 2.5/500mg Tablet is not recommended for use in patients with severely reduced kidney functions. Therefore, consult your doctor before taking it.
Adlinameg 2.5/500mg Tablet is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gallstones. Therefore, consult your doctor before taking it.
Adlinameg 2.5/500mg Tablet operates through the synergy of its active components. Metformin reduces liver glucose production, delays sugar absorption in the intestine, and enhances insulin responsiveness. Linagliptin boosts insulin secretion from the pancreas and curbs hormones elevating blood sugar. As a result, both fasting and post-meal blood sugar levels are lowered, contributing to effective blood sugar control.
Type 2 Diabetes Mellitus (DM) arises from elevated blood sugar levels due to reduced insulin production and inadequate response to insulin in your body. Adlinameg 2.5/500mg Tablet is employed to manage Type 2 Diabetes Mellitus by addressing these issues.
Linagliptin is prescribed to assist individuals with type 2 diabetes in regulating their blood sugar levels. It inhibits DPP-4 (dipeptidyl peptidase-4), an enzyme responsible for breaking down GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), which are incretin hormones. By inhibiting DPP-4, Linagliptin enhances the release of insulin from pancreatic beta cells in response to glucose levels. Additionally, it reduces the production of glucagon from pancreatic alpha cells, leading to higher active incretin hormone concentrations.
Metformin Hydrochloride is a medication from the biguanide class used to treat type 2 diabetes. It affects both baseline and postprandial (after-meal) plasma glucose levels. Unlike sulfonylureas, it doesn't cause hypoglycemia. Metformin Hydrochloride acts by lowering hepatic glucose synthesis, decreasing intestinal glucose absorption, and enhancing insulin sensitivity. This is achieved by boosting peripheral glucose uptake and utilization.
Linagliptin + Metformin Hydrochloride can interact with several drugs, foods, and medical conditions:
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If you are allergic to linagliptin and metformin or any other ingredient of this medicine. It should not be used by a patient with type 1 diabetes mellitus. It is not suitable for a patient undergoing the treatment of diabetic ketoacidosis. It should be used with caution as age increases. If you have any kind of pre-existing medical condition such as kidney or liver impairment, pancreas disorder, etc.
Due to the lack of sufficient and well-controlled trials involving pregnant women, the use of this combination medication or its individual components should only be considered if absolutely necessary during pregnancy. If administered to a nursing woman, it should be done with extreme caution. It's important to consult a healthcare professional for guidance in such situations.
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