Aptin 50mg 10pcs - ePharma
0 Items
0

Leading Online Pharmacy of Bangladesh

thumbnail


✔ 100% Authentic Product

👁️ Currently Viewing 603


Aptin 50mg 10pcs

Generic: Vildagliptin

Type: Tablet

Pack Size: 10 Pcs

Generic Name: Vildagliptin 50mg, 

Manufacturer: ACI Limited.

Offer

Discount Price: ৳ 194
MRP: ৳ 200 3% Off

🎉 Save  ৳: 6  in this Product



100% Genuine Products, Guaranteed

Safe & Secure Payments, Always

Fast, Secure & Efficient Delivery

Proper Packaging


  • Cash on Delivery - All over Bangladesh
  • Regular Delivery - 8-12 Hours, Dhaka City*
  • Regular Delivery - 24-48 Hours, All Over Bangladesh*

✅ Description:

Indications

Vildagliptin is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus as monotherapy and in dual combination with Metformin, a Sulphonylurea, a Thiazolidinedione, or Insulin when diet, exercise, and a single antidiabetic agent do not result in adequate glycemic control.

Pharmacology

Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which is believed to exert its actions in patients with type 2 diabetes by slowing the inactivation of incretin hormones. Incretin hormones, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released by the intestine throughout the day, and levels are increased in response to a meal. These hormones are rapidly inactivated by the enzyme, DPP-4. The incretins are part of an endogenous system involved in the physiologic regulation of glucose homeostasis. When blood glucose concentrations are normal or elevated, GLP-1 and GIP increase insulin synthesis and release from pancreatic beta cells by intracellular signaling pathways involving cyclic AMP. GLP-1 also lowers glucagon secretion from pancreatic alpha cells, leading to reduced hepatic glucose production. By increasing and prolonging active incretin levels, Vildagliptin increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner.

Dosage & Administration

The recommended dose of Vildagliptin is-

  • 50 mg or 100 mg daily for monotherapy.
  • 50 mg twice daily (morning and evening) when used in dual combination with Metformin or a Thiazolidinedione;
  • 50 mg once daily in the morning when used in dual combination with Sulphonylurea.

Vildagliptin may be taken with or without a meal. No dosage adjustment is required in the elderly, or in patients with mild renal impairment.

Pediatric use: Vildagliptin is not recommended in patients 18 years of age.

Interactions

In pharmacokinetic studies, no interactions were seen with pioglitazone, metformin, glibenclamide, digoxin, warfarin, amlodipine, ramipril, valsartan, or simvastatin. As with other oral antidiabetic medicinal products, the glucose-lowering effect of Vildagliptin may be reduced by certain active substances, including thiazides, corticosteroids, thyroid products, and sympathomimetics.

Contraindications

Vildagliptin is contraindicated in patients with:

Patients with moderate to severe renal impairment

Patients with type 1 diabetes

Hypersensitivity to the active substance or to any of the excipients

Patients with Hepatic Impairment: Patients with pre-treatment alanine aminotransferase (ALT) or aspartate aminotransferase (AST) >3 times the upper limit of normal (ULN).

Side-Effects

The majority of adverse reactions were mild and transient, not requiring treatment discontinuations. A rare case of hepatic dysfunction is seen. Clinical trials of up to and more than 2 years duration did not show any additional safety signals or unforeseen risks when using this combination.

Pregnancy

There are no adequate data on the use of Vildagliptin in pregnant women; hence the potential risk for humans is unknown.

Precautions

Caution should be exercised in patients aged 75 years and older due to limited clinical experience. It is recommended that LFTs are monitored prior to initiation of Vildagliptin, at three-monthly intervals in the first year and periodically thereafter. If transaminase levels are increased, patients should be monitored with a second liver function evaluation to confirm the finding and be followed thereafter with frequent liver function tests until the abnormality returns to normal. If AST or ALT persists at 3xULN, Vildagliptin treatment should be stopped. Patients who develop jaundice or other signs of liver dysfunction should discontinue Vildagliptin. Following the withdrawal of treatment with Vildagliptin and LFT normalization, treatment with Vildagliptin should not be reinitiated. Due to limited clinical experience, use with caution in patients with congestive heart failure of New York Heart Association (NYHA) functional class I-II, and do not use in patients with NYHA functional class III-IV. Vildagliptin is not recommended in patients with moderate to severe renal impairment.

Storage Conditions

Store below 30°C temperature & keep away from light & moisture. Keep out of reach of children.

Offer

Relevant Products / প্রাসঙ্গিক পণ্য

Frequently Asked Questions (FAQs) ❓

🛒 Orders

+ Q. How can I place an order?

You can place an order on ePharma by searching for your desired product using the search bar, adding it to your cart, and proceeding to checkout.

+ Q. How can I track my order?

You can track your order by logging into your account or using the tracking link provided in your email or SMS.

+ Q. Can I cancel my order?

Yes, you can cancel your order before it is shipped. Contact customer support for assistance.

📦 Delivery

+ Q. What is the delivery time?

Delivery typically takes 1-2 business days, depending on your location.

+ Q. Does ePharma deliver internationally?

Currently, ePharma only delivers within Bangladesh.

💳 Purchase and Payment

+ Q. What payment methods are accepted?

We accept debit/credit cards, Bkash, Nagad, and cash on delivery.

+ Q. Is it safe to pay on ePharma?

Yes, we use SSL encryption to protect your data.

🎁 Discounts & Promotions

+ Q. Does ePharma offer discounts?

Yes, we regularly offer discounts and promotions. Follow us on social media for updates.

💊 Products & Prescriptions

+ Q. Are the medicines genuine?

Yes, all medicines are sourced from licensed pharmaceutical companies.

+ Q. Can I buy over-the-counter medication?

Yes, you can purchase over-the-counter medication on ePharma.

🔙 Return

+ Q. Can I return or exchange products?

Yes, you can return or exchange damaged or incorrect products. Contact customer support for assistance.

🔒 Privacy & Security

+ Q. How does ePharma protect my data?

We use advanced security measures to protect your personal and financial information. Read our privacy policy for details.
Ratings & Reviews

No review

Check our pricing section for Aptin 50mg 10pcs price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

Hi, there!