Diapro 80mg Tablet 15pcs

Uses of Diapro 80mg Tablet

• Treatment of Type 2 diabetes mellitus

How does Diapro 80mg Tablet work?

It works by increasing the amount of insulin released by the pancreas in order to lower the blood sugar levels.

Side Effects of Diapro 80mg Tablet

• Flatulence
• Diarrhea
• Headache
• Nausea
• Dizziness
• Hypoglycemia (low blood glucose level)

Quick Suggestions:

• Take Gliclazide as directed by your doctor.
• The medicine should be taken orally 30 minutes before breakfast.
• You should monitor your blood sugar levels regularly.
• Always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels.

Indications:

Gliclazide Tabletsis an anti-diabetic medication. It works by increasing the amount of insulin the pancreas releases to lower blood sugar levels.

Pharmacology

Gliclazide is a second-generation sulfonylurea drug that has hypoglycaemic and potentially useful hematological properties. It stimulates the release of insulin from pancreatic β-cells by facilitating Ca+2  transport across the β-cell membranes and decreases hepatic glucose output.

Dosage & Administration of Diapro 80mg Tablet

The initial dose is typically 40 to 80 mg daily, which can be increased up to 320 mg daily in divided doses if needed. It should be taken before meals.

Interaction

Interactions with Other Medicines:

• Inform your doctor or pharmacist if you are taking or have recently taken any other medicines.
• Increased Effect: Medicines that may strengthen Gliclazide's effect and cause low blood sugar include:
  • Other anti-diabetics (oral or insulin)
  • Antibiotics (e.g., sulphonamides, clarithromycin)
  • Blood pressure or heart failure medications (e.g., beta-blockers, ACE inhibitors)
  • Antifungal medicines (e.g., miconazole, fluconazole)
  • Ulcer treatments (e.g., H2 receptor antagonists)
  • Antidepressants (e.g., MAO inhibitors)
  • Painkillers or anti-rheumatics (e.g., phenylbutazone, ibuprofen)
  • Alcohol-containing medicines
• Decreased Effect: Medicines that may weaken Gliclazide's effect and raise blood sugar levels include:
  • Central nervous system treatments (e.g., chlorpromazine)
  • Anti-inflammatory drugs (e.g., corticosteroids)
  • Asthma or labor medications (e.g., intravenous salbutamol)
  • Medicines for breast disorders or heavy menstrual bleeding (e.g., danazol)
  • St John's Wort (Hypericum perforatum) preparations
• Blood Glucose Disturbances: Fluoroquinolone antibiotics may cause blood sugar disturbances when taken with Gliclazide, especially in elderly patients.
• Increased Anticoagulant Effect: Gliclazide may increase the effects of blood-thinning medicines like warfarin.
• Consultation Required: Always consult your doctor before starting any new medication.

Food, Drink, and Alcohol:

• Food: Gliclazide can be taken with food and non-alcoholic drinks.
• Alcohol: Avoid alcohol as it can unpredictably alter blood sugar control.

Driving and Using Machines:

• Blood sugar fluctuations can impair concentration and reaction times, which may affect driving or operating machinery.
• Avoid driving if you frequently experience low blood sugar or lack warning signs of low blood sugar.

Contraindications

Do not take Gliclazide if you:

• Are allergic to it or similar medicines (sulfonylureas or hypoglycaemic sulfonamides)
• Have type 1 diabetes
• Have diabetic ketoacidosis, diabetic pre-coma, or coma
• Have severe kidney or liver disease
• Are taking antifungal medications
• Are breastfeeding

Pregnancy & Lactation

Gliclazide is not recommended during pregnancy or breastfeeding. Consult your doctor for advice.

Precautions & Warnings

• Treatment Plan: Follow your prescribed treatment plan, including regular blood sugar monitoring, dietary regimen, physical exercise, and weight management.
• Hypoglycaemia Risk: Increased risk during the first weeks of treatment, irregular meals, fasting, malnutrition, increased physical activity, alcohol consumption, and certain other medications or conditions.
• Hyperglycaemia Risk: If Gliclazide does not sufficiently reduce blood sugar or in case of stress situations, symptoms like thirst, frequent urination, dry mouth, and skin infections may occur.
• Blood Glucose Monitoring: Especially important when taking fluoroquinolone antibiotics.
• G6PD Deficiency: Patients with this hereditary condition may experience hemolytic anemia. Consult your doctor before taking Gliclazide.
• Children: Not recommended due to lack of data

Storage Conditions:

• Store below 30°C and keep out of reach of children.
• Do not use past the expiry date.
• Dispose of it properly to protect the environment.