Type: Tablet. Galvus Met 50mg/850mg is a prescription medication used for the management of Type 2 Diabetes Mellitus. This oral antidiabetic combines Metformin and Vildagliptin to effectively control blood sugar levels.
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Galvus Met 50mg/850mg is a potent combination therapy for Type 2 Diabetes Mellitus, uniting two antihyperglycemic agents: Metformin and Vildagliptin. This synergistic formulation offers comprehensive glycemic control through complementary mechanisms:
Dosage and Administration:
Initiate Galvus Met 50mg/850mg based on the patient's current Metformin dosage. Typically, one tablet is administered twice daily with meals to reduce gastrointestinal side effects. The maximum recommended daily dose is 100mg of Vildagliptin and 2000mg of Metformin. Adjustments should be individualized based on efficacy and tolerability.
Drug Interactions:
Co-administration with other antidiabetic agents may enhance the hypoglycemic effect. Notably, Vildagliptin has a low potential for drug interactions as it neither inhibits nor induces cytochrome P450 enzymes. However, caution is advised when combining with medications that may affect renal function or have significant renal excretion.
Contraindications:
Side Effects:
Common adverse reactions include:
Pregnancy and Lactation:
The use of Galvus Met 50mg/850mg during pregnancy is not recommended due to limited human data. Animal studies have shown reproductive toxicity with Vildagliptin. It is unknown whether Vildagliptin or Metformin is excreted in human milk; therefore, a decision should be made to discontinue nursing or discontinue the drug, considering the importance to the mother.
Precautions and Warnings:
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Note: Always consult healthcare professionals for personalized medical advice.
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