Marzev is prescribed for adults with type 2 diabetes to help manage blood sugar levels.
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Omarigliptin is a long-acting inhibitor of the enzyme Dipeptidyl Peptidase-4 (DPP-4). DPP-4 breaks down incretin hormones, which play a key role in regulating blood glucose by stimulating insulin release and reducing glucagon secretion after meals. By inhibiting DPP-4, Omarigliptin enhances the activity of incretin hormones, helping to maintain proper blood sugar levels.
Dipeptidyl Peptidase-4 (DPP-4) Inhibitor
Route: Oral
Recommended Dose: 25 mg once weekly, either alone or in combination with other anti-diabetic medications, to optimize blood sugar control.
Missed Dose: Take the missed dose as soon as possible and continue the regular weekly schedule. Do not double the dose.
Renal Impairment:
Severe kidney failure or end-stage renal disease:
Men (CrCl > 1.9): 12.5 mg once weekly
Women (CrCl > 1.4): 12.5 mg once weekly
Children & Adolescents: Safety and effectiveness have not been established.
Marzev may interact with medications such as metformin, glimepiride, oral contraceptives, and atorvastatin. Use caution when combined with insulin or sulfonylureas due to the risk of low blood sugar. Certain medications may increase or decrease Marzev’s effect, so blood glucose should be monitored carefully.
There is limited data on the use of Omarigliptin during pregnancy. Use only if the benefits outweigh potential risks. Breastfeeding is not recommended while taking this medication.
Use Marzev cautiously in individuals with conditions that may increase the risk of low blood sugar, such as:
Keep Marzev in a cool, dry place below 30°C, away from light and out of reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.