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PREGABALIN:
Conditions Causing Neuropathic Pain:
Special Considerations:
Avoid alcohol consumption, as it may exacerbate dizziness.
Avoid driving or operating heavy machinery if experiencing dizziness or sleepiness after taking the capsule.
Relieves pain by reducing the release of pain signal transmitting chemicals in the brain.
Pregabalin acts as a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), but it doesn't directly bind to GABAA, GABAB, or benzodiazepine receptors. Instead, it exhibits a high affinity for the alpha-2-delta subunit, which is an auxiliary component of voltage-gated calcium channels in tissues of the central nervous system. The oral bioavailability of Pregabalin exceeds 90%, and its elimination from the systemic circulation primarily occurs through renal excretion as an unchanged drug. The half-life of Pregabalin is approximately 6.3 hours in individuals with normal renal function.
Adult Dose:
Oral Neuropathic Pain, Postherpetic Neuralgia:
Diabetic Peripheral Neuropathic Pain:
Adjunct in Partial Seizures:
Fibromyalgia:
Child Dose:
Safety and efficacy not established.
Renal Dose:
Renal Impairment: Haemodialysis:
CrCl (ml/min) Dosage Recommendation:
Before taking Neugalin 50mg Capsule, inform your doctor if you are taking any of the following medicines such as:
Store in a cool and dry place away from sunlight
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.