Neugalin XR 82.5mg Capsule | Pregabalin | Price | Substitutes | ePharma
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Neugalin XR 82.5mg Capsule

Generic: Pregabalin

Type: Capsule

Pack Size: 10pcs

Neugalin XR 82.5mg is a medication used to relieve pain caused by nerve damage (neuropathic pain) due to conditions like diabetes, shingles, spinal cord injury, and others. It is also used to treat muscle pain and stiffness in fibromyalgia and certain types of seizures in combination with other medicines.


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Discount Price: ৳ 241.8
MRP: ৳ 260 7% Off

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✅ Description:

Pregabalin, the active ingredient in Neugalin XR 82.5mg Capsule, is categorized as an anticonvulsant medication. Its primary applications include the prevention of neuropathic pain, treatment of epilepsy (seizure episodes), management of fibromyalgia (musculoskeletal pain), and relief from neuralgia (pain associated with damaged or irritated nerves). Neuropathic pain, a condition characterized by chronic nerve pain, can result from various diseases like diabetes, shingles, spinal cord injury, or injuries to tissues, muscles, or joints.

Pregabalin, containing Pregabalin, acts by calming damaged or overactive nerves in the body, addressing nerve-related pain and seizures. Additionally, it reduces the transmission of pain signals from damaged nerves.

Safety Advices


Alcohol
UNSAFE

Pregabalin consumption is unsafe, as it causes excessive drowsiness with alcohol.


Pregnancy
CONSULT YOUR DOCTOR
  • Pregabalin is not recommended for use during pregnancy unless deemed necessary by a healthcare professional.
  • If you are pregnant or planning to become pregnant, it is crucial to consult with your doctor for a thorough evaluation of the potential benefits and risks.

Breastfeeding
CONSULT YOUR DOCTOR
  • Pregabalin is not recommended for use while breastfeeding.
  • It passes into breast milk, and the potential impact on the nursing infant should be carefully considered.
  • If you are breastfeeding, consult with your doctor to discuss alternative options or potential risks.

Driving
UNSAFE

Use of Pregabalin may increase the risk of drowsiness, dizziness, difficulty in concentrating, etc. Hence, avoid performing activities such as driving or operating machines if you experience any of these symptoms.


Kidney
CAUTION
  • Caution is advised in individuals with kidney problems, as Pregabalin is excreted through the urine.
  • Close monitoring of kidney function is recommended during Pregabalin use.
  • Your doctor may suggest dose adjustments or alternative treatments based on your kidney function and overall clinical condition.

Liver
CONSULT YOUR DOCTOR

No specific information is available for this.

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✔️ Uses:
  • Neuropathic pain
  • Epilepsy/Seizures
  • Fibromyalgia
  • Anxiety (in generalized anxiety disorder)
✔️ How does Neugalin XR 82.5mg Capsule work?

Neugalin XR 82.5 is believed to work by reducing abnormal electrical activity in the brain for epilepsy, interfering with pain signals for neuropathic pain, and stopping the release of certain chemical messengers for anxiety.

✔️ Side Effects of Neugalin XR 82.5mg Capsule

Common side effects include blurred vision, difficulty paying attention, dizziness, dry mouth, edema (swelling), sleepiness, and weight gain.

✔️ Quick Suggestions:
  • Regularly monitor for visual disturbances.
  • Observe for clinical worsening, suicidality, and unusual changes in behavior, especially in those with a history of mood disorders.
  • The duration of treatment depends on the condition being treated.
  • Inform your doctor about other medications you're taking, especially painkillers, anxiety medicines, and drugs for controlling high blood sugar.
✔️ Indication

Pregabalin is utilized in the treatment of various conditions, including:

  1. Diabetic Neuropathy: Nerve damage caused by diabetes.
  2. Postherpetic Neuralgia: Persistent pain in areas previously affected by the herpes zoster virus.
  3. Epilepsy: A condition characterized by abnormal brain activity, leading to seizures.
  4. Fibromyalgia: A chronic condition causing widespread pain, stiffness, and other symptoms.
  5. Neuropathic Pain: Pain resulting from nerve injury or damage.
  6. Generalized Anxiety Disorder: Chronic worry, overthinking, and other symptoms of anxiety.
✔️ Pharmacology:

Pregabalin is a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Unlike direct binding to GABAA, GABAB, or benzodiazepine receptors, it exhibits a high affinity for the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. With an oral bioavailability exceeding 90%, it is dose-independent. The drug is primarily eliminated through renal excretion in its unchanged form, featuring a half-life of approximately 6.3 hours in individuals with normal renal function.

✔️ Dosage & Administration of Neugalin XR 82.5mg Capsule

Adult Dose:

Neuropathic pain, Postherpetic Neuralgia:

  • Initially: 150 mg/day
  • May increase to 300 mg/day after 3-7 days.
  • Maximum: 600 mg/day after a 7-day interval.
  • All doses to be given in 2 or 3 divided doses.

Diabetic Peripheral Neuropathic Pain:

  • Initial: 50 mg PO q8hr
  • Maintenance: May increase to 100 mg PO q8hr within 1 week, as needed.
  • Not to exceed 300 mg/day

Adjunct in partial seizures:

  • Initially: 150 mg/day
  • May increase to 300 mg/day after a week.
  • Maximum: 600 mg/day.
  • All doses to be given in 2 or 3 divided doses.

Fibromyalgia:

  • Initially: 150 mg/day
  • May increase to 300 mg/day after a week.
  • Maximum: 450 mg/day, if needed.
  • All doses to be given in 2 or 3 divided doses.

Child Dose: Safety and efficacy not established.

Renal Dose for Renal Impairment:

Hemodialysis:

  • 25-100 mg immediately after each 4-hr hemodialysis session.

CrCl (ml/min) Dosage Recommendation:

  • 30 to <60: 75 mg/day. Max: 300 mg/day. All doses to be given in 2 or 3 divided doses.
  • 15 to <30: Initially, 25-50 mg/day. Max: 150 mg/day. All doses are to be given as a single dose or in 2 divided doses.
  • <15: Initially, 25 mg/day. Max: 75 mg/day. All doses are to be given as a single dose.

Take Neugalin XR 82.5 as prescribed by your doctor, with or without food. It's important to take it at the same time each day. The initial dose is usually low and may be increased gradually. Missing a dose should be avoided, but if you forget, take it as soon as possible

✔️ Interaction

Lorazepam:

Report the use of Lorazepam or any other medicine that you take for sleep disorders or anxiety problems. The risk of adverse effects like dizziness, drowsiness, confusion, lack of focus, etc., is very high while taking these medicines together. Special precaution is advised if these medicines are taken by an elderly person.

Pioglitazone:

Report the use of Pregabalin to the doctor before receiving Pioglitazone or any other medicine used for controlling high blood sugar levels. These medicines could increase the risk of weight gain, fluid retention, and heart failure when taken together. You may need a dose adjustment and frequent monitoring to safely use these medicines together.

Ramipril:

Report the use of Ramipril or any other medicine belonging to the class of ACE inhibitors used for lowering blood pressure. The risk of fluid retention and associated adverse effects on the heart are significantly increased when these medicines are used together.

Oxycodone:

Report the use of any opiate pain medicines to the doctor before receiving Pregabalin. Using these medicines together can cause severe dizziness, confusion, lack of coordination especially in the elderly and people with a history of emotional disturbances, suicidal thoughts, alcohol abuse, or drug abuse. Any such effect while using them together should be reported to the doctor.

Interaction with Disease:

Angioedema:

This medicine should be administered with caution in patients who have a history of or are at risk of developing swellings of the inner layers of the skin. These swellings can cause airway blockage and prove life-threatening.

✔️ Contraindications
✔️ Pregnancy & Lactation
✔️ Precautions & Warnings
  •  
  • Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
  • Be cautious while driving, as Neugalin XR 82.5 may cause sleepiness and dizziness.
  • Avoid alcohol consumption, as it can enhance drowsiness.
✔️ Storage Conditions

Keep in a cool & dry place (below 30° C), protected from light & moisture. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

Yes, this drug may cause weight gain because it increases your hunger. Consult a dietician if you have any further concerns to keep your weight stable.

No

Neugalin XR 82.5mg Capsule is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of clinical safety data. Therefore, consult your doctor for advice.
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Check our pricing section for Neugalin XR 82.5mg Capsule price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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