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Targaba 15 Tablet 1 Strip
Targaba 15 Tablet
Generic Name: Mirogabalin Besylate
Strength: 15 mg
Manufacturer: Opsonin Pharma Limited
Targaba (Mirogabalin Besylate) is indicated for the management of neuropathic pain, including:
- Diabetic Peripheral Neuropathic Pain (DPNP)
- Postherpetic Neuralgia (PHN)
- Peripheral Neuropathic Pain (PNP)
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✅ Description:
Mirogabalin exhibits high selectivity for the α2δ subunits of voltage-gated calcium channels (VGCCs), particularly in the dorsal root ganglion (DRG). By reducing calcium ion influx, it suppresses the release of neurotransmitters at presynaptic nerve terminals, effectively decreasing neural hyperexcitability and relieving neuropathic pain.
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✔️ Dosage & Administration
Adults: Start with 5 mg twice daily. The dose may be increased in 5 mg increments weekly, up to a maximum of 15 mg twice daily.
The effective dose typically ranges between 10 mg and 15 mg twice daily, adjusted based on age and clinical response.
✔️ Side Effects
Common side effects may include:
- Drowsiness (somnolence)
- Dizziness
- Peripheral edema
- Weight gain
Rare but serious reactions:
Impaired consciousness, fainting, or excessive drowsiness
Symptoms of liver dysfunction: fatigue, loss of appetite, nausea, vomiting, and jaundice
Discontinue use and consult a healthcare provider immediately if any of these occur.
✔️ Drug Interactions
Mirogabalin does not inhibit or induce cytochrome P450 (CYP) enzymes.
Co-administration with Cimetidine or Probenecid may increase plasma levels of Mirogabalin.
Combined use with alcohol or lorazepam may enhance central nervous system (CNS) depression. Caution is advised.
✔️ Contraindications
Known hypersensitivity to Mirogabalin.
Patients with mild to moderate hepatic or renal impairment.
✔️ Precautions & Warnings
- May cause dizziness, drowsiness, or fainting—avoid driving or operating heavy machinery.
- Use with caution in elderly patients due to increased fall risk.
- May cause visual disturbances such as blurred or double vision.
- Risk of weight gain with prolonged use.
- Always inform your physician of all medications being taken before starting Targaba
✔️ Storage:
Store below 30°C in a dry place, away from direct light and moisture.
Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
