Insul TM Glargine | 100IU/ml | SC Injection | 3ml Vial | ePharma
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Insul TM Glargine 100IU/ml SC Injection-3ml Vial

Generic: Insulin Glargine (rDNA)

Type: Injection

Pack Size: 1 Pc

Insul TM Glargine is indicated for once-daily subcutaneous administration for the treatment of adult and pediatric patients with type 1 diabetes mellitus or adult patients with type 2 diabetes mellitus who require basal (long-acting) insulin for the control of hyperglycemia.


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Discount Price: ৳ 570
MRP: ৳ 600 5% Off

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✅ Description:

Insul TM Glargine 100IU/ml SC Injection 3ml is a synthetic insulin-containing insulin glargine, designed to mimic human insulin. Used to treat diabetes in adults and children aged two years and above, it ensures steady blood sugar control without peaks. This long-acting insulin takes around 2 hours to begin working and lasts up to 24 hours.

Your doctor will determine your dosage based on lifestyle, blood sugar tests, and previous insulin use. Injection site reactions and hypoglycemia may occur, but most resolve over time. Don't stop using it abruptly, and inform your doctor if you experience persistent side effects.

Avoid using Insul TM Glargine 100IU/ml SC Injection for low blood sugar, kidney/liver/heart issues, or alcohol/drug problems. Complement it with a healthy diet, regular exercise, and weight management. 

Safety Advices


Alcohol
UNSAFE

Taking Insulin Glargine with alcohol may affect blood glucose levels in patients with diabetes.


Pregnancy
CONSULT YOUR DOCTOR

Insul TM Glargine 100IU/ml SC Injection 3ml may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

Insul TM Glargine 100IU/ml SC Injection 3ml  is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amounts or is not expected to cause toxicity to the baby.


Driving

Insul TM Glargine 100IU/ml SC Injection 3ml may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.


Kidney

Insul TM Glargine 100IU/ml SC Injection 3ml should be used with caution in patients with kidney disease. Dose adjustment of Insul TM Glargine 100IU/ml SC Injection 3ml may be needed. Please consult your doctor. Regular monitoring of blood glucose levels is recommended for dose adjustment.


Liver

Insul TM Glargine 100IU/ml SC Injection 3ml should be used with caution in patients with liver disease. A dose adjustment of Insul TM Glargine 100IU/ml SC Injection 3ml may be needed. Please consult your doctor. Regular monitoring of glucose levels is recommended for dose adjustment.

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✔️ Uses of Insul TM Glargine 100IU/ml SC Injection
  • Type 1 Diabetes mellitus
  • Type II Diabetes Mellitus
✔️ How does Insul TM Glargine 100IU/ml SC Injection work?

Insul TM Glargine 100IU/ml SC Injection is a long-acting modified form of insulin that works similarly to human insulin. It improves blood sugar control by enhancing glucose uptake from the blood into body tissues and also by preventing the production of glucose in the liver.

✔️ Side Effects of Insul TM Glargine 100IU/ml SC Injection

Hypoglycemia (low blood sugar level), Injection site allergic reaction.

✔️ Quick Suggestions:
  • Insul TM Glargine 100IU/ml SC Injection 3ml is administered subcutaneously, meaning it's injected under the skin. It's important to inject it once daily at the same time every day.
  • Injecting it in the abdomen's skin results in quicker absorption compared to other injection sites.
  • Rotate injection sites to prevent the development of hard lumps at one particular site.
  • Incorporate regular exercise, a balanced diet, and other prescribed diabetes medicines into your routine.
  • Hypoglycemia (low blood sugar) is a common side effect. Hence, diligent blood sugar monitoring is necessary while using this medication.
  • Keep high-sugar foods such as sugar candy, glucose candy, fruit juice, and glucose on hand to address hypoglycemia symptoms like cold sweats, pale skin, tremors, weakness, and anxiety.
  • Once opened, vials/cartridges remain viable at room temperature for up to 4 weeks. Unopened vials should be refrigerated (2°C–8°C).
  • Do not use if the solution is no longer clear and colorless, or if it contains particles.
✔️ Indication of Insul TM Glargine 100IU/ml SC Injection

Insulin Glargine is employed to manage both Type 1 Diabetes mellitus and Type 2 Diabetes Mellitus:

Type 1 Diabetes Mellitus: 

In this lifelong condition, the pancreas fails to produce enough insulin to regulate blood sugar levels. Insulin Glargine is used to supplement inadequate insulin production and maintain appropriate blood sugar levels.

Type 2 Diabetes Mellitus: 

This chronic condition involves cells being unable to effectively use the insulin produced by the body, leading to improper conversion of glucose into energy. Insulin Glargine helps in managing blood sugar levels by providing the needed insulin support to overcome this resistance.

✔️ Pharmacology

Insulin Glargine is a sterile solution for subcutaneous injection, designed to lower blood glucose levels. It's a long-acting insulin with up to 24 hours duration, produced using recombinant DNA technology. Its mechanism involves enhancing glucose absorption in muscles and fat, lowering hepatic glucose production, and supporting protein synthesis while inhibiting lipolysis and proteolysis.

✔️ Dosage & Administration of Insul TM Glargine 100IU/ml SC Injection
  • Insul TM Glargine, a recombinant human insulin analog, offers consistent glucose-lowering effects over 24 hours, allowing for once-daily administration.
  • Its potency is comparable to human insulin. Administered subcutaneously, InsulTM Glargine should be given at the same time daily, avoiding intravenous use to prevent severe hypoglycemia.
  • Blood glucose monitoring is essential, and dosing should be personalized.
  • Site rotation for injection (abdomen, thigh, deltoid) is crucial to maintain insulin absorption.
  • Exercise and other factors can influence onset and duration. Not suitable for diabetic ketoacidosis; short-acting insulin is preferred.
  • Pediatric patients above 6 years can safely use it; those below 6 have limited study data. InsulTM Glargine can be initiated similarly to adults, adjusting as needed.
  • Dosage modification might be required during illnesses, changes in physical activity, diet, and insulin switch.
✔️ Interaction

Interactions with Other Medicines:

  • Symptoms of low blood sugar may occur if you are taking other diabetes medications, depression medications like fluoxetine, as well as fever and pain relievers like salicylates, ramipril, and lisinopril.
  • High blood sugar might result from taking oral contraceptives, thiazides, steroids, thyroxine, medicines used for severe diarrhea, and treatments for abnormal organ growth like octreotide and lanreotide.
  • Caution is advised if taking pioglitazone for diabetes, as some cases of heart attack and heart failure have been reported.
  • Certain medications can block your body's response to low blood sugar, leading to a serious drop in blood sugar. Inform your doctor if you are on medications like Beta-blockers (Metoprolol, Propranolol, Atenolol), Clonidine, Guanethidine, and Reserpine.

Interactions with Food Items:

  • Insul TM Glargine 100IU/ml SC Injection 3ml be taken 15 minutes before or after meals.
  • Maintaining a consistent meal pattern is recommended while taking insulin.
  • Avoid skipping or delaying meals when using insulin.
✔️ Contraindications
  • If you are allergic to insulin or any of the ingredients of this medicine
  • If you are suffering from hypoglycemia (low blood sugar level).
✔️ Pregnancy & Lactation

Clinical studies on the use of insulin glargine in pregnant women have not been well-controlled. It's crucial for individuals with diabetes or a history of gestational diabetes to maintain optimal metabolic control before conception and throughout pregnancy. Insulin requirements may vary, typically decreasing in the first trimester, increasing in the second and third trimesters, and rapidly decreasing post-delivery. Close monitoring of glucose control is vital in these cases.

Due to the limited predictive value of animal studies for human response, insulin glargine should only be used during pregnancy if clearly necessary. The extent of insulin glargine excretion in human milk is unknown, but it's noted that various drugs, including human insulin, are present in human milk. Thus, caution is advised when administering InsulTM Glargine to nursing women, who might require insulin dose and diet adjustments.

✔️ Precautions & Warnings

Hypoglycemia, characterized by low blood sugar levels, is a common adverse effect of insulin therapies, including Insul TM Glargine. The timing of hypoglycemia may vary among different insulin formulations. Regular glucose monitoring is advised for all diabetes patients. Any changes in insulin should be done cautiously under medical supervision. Alterations in insulin strength, dosing timing, manufacturer, type, species, or manufacturing method may necessitate dosage adjustments. InsulTM Glargine should not be mixed with other insulins or solutions to avoid unpredictable changes in its pharmacokinetics and pharmacodynamics. Intravenous administration of InsulTM Glargine is prohibited due to the risk of severe hypoglycemia.

The onset and duration of Insul TM Glargine's action can vary based on factors such as blood supply, temperature, and physical activity. Insulin might cause sodium retention and edema, especially if improved metabolic control leads to intensified therapy. Hypoglycemic reactions can occur with all insulin preparations, particularly in cases of rapid changes in blood glucose levels. Early warning signs of hypoglycemia may vary under certain conditions. Renal impairment can reduce insulin requirements, while hepatic impairment doesn't affect InsulTM Glargine's absorption but may require dose adjustments.

✔️ Storage Conditions

Store uInsul TM Glargine 100IU/ml SC Injection 3ml in the fridge (2-8°C), avoiding the freezer, to maintain its effectiveness.

Frequently Asked Questions (FAQ)

Insul TM Glargine 100IU/ml SC Injection 3ml begins to show its effect within 1.5 to 2 hours after administration.

The effect of Insul TM Glargine 100IU/ml SC Injection 3ml lasts for an average duration of 24 hours.

The active substance is insulin glargine. Each ml of the solution contains 100 units of insulin glargine (equivalent to 3.64 mg).

Insul TM Glargine 100IU/ml SC Injection 3ml is generally safe to take for a long time. In fact, it works best if you take it for many months or even years.

Insul TM Glargine 100IU/ml SC Injection 3ml is intended for subcutaneous injection, which means it should be injected under the skin. It is not suitable for intravenous administration or injection into veins. The preferred injection site is the subcutaneous region of the abdomen (stomach). However, you can also administer Insul TM Glargine 100IU/ml SC Injection 3ml in the upper arm or thigh region. Remember to rotate injection sites to prevent the development of hard lumps at a single site.
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Check our pricing section for Insul TM Glargine 100IU/ml SC Injection-3ml Vial price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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