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Azelaic Acid 20% topical is classified as an "anti-acne medication" and is primarily used to treat acne (pimples) and rosacea (redness and visible blood vessels on the face). Azelaic Acid has several properties, including antibacterial, keratolytic (removing warts, calluses, and lesions), comedolytic (inhibiting blemish formation), and antioxidant activities. It is effective in clearing bumps, lesions, and swelling caused by rosacea. Acne occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of whiteheads, blackheads, and pimples. Rosacea is a skin condition characterized by redness, flushing, and the presence of pimples on the face.
Azelaic Acid contains the active ingredient 'Azelaic acid,' which acts as a bactericidal agent, killing bacteria. It works by inhibiting the synthesis of microbial cellular proteins. Azelaic Acid helps clear pores of bacteria that cause irritation and breakouts and reduces inflammation, making acne less visible, less red, and less irritated. It also aids in skin renewal and reduces the formation of pimples and blackheads.
Azelaic Acid is intended for external use only and should be avoided in contact with the eyes, eyelids, lips, mouth, and nose. If accidental contact occurs in these areas, immediate rinsing with water is recommended.
No interaction was found/established.
Please consult your doctor before using Azelec Cream if you are pregnant or planning to conceive.
There are limited studies on how Azelec Cream affects breastfed infants. Please consult your doctor before using Azelec Cream if you are breastfeeding. If you need to apply the cream or lotion on your breasts, don't do this shortly before giving a feed.
Azelec Cream usually does not interfere with your driving ability and is safe to use.
Let your doctor know if you have any history of kidney diseases before using Azelec Cream.
Let your doctor know if you have any history of liver diseases before using Azelec Cream.
In rare instances, local skin irritation (such as redness, scaling, itching, or burning) may occur, typically at the beginning of treatment. However, these discomforts are generally mild and tend to diminish as the treatment progresses.
Azelec Cream combats Propionibacterium acnes, a type of bacteria that plays a pivotal role in the development of acne. It additionally inhibits the growth of tough outer skin cells (keratin surface cells) that obstruct skin pores, leading to the formation of blackheads and whiteheads.
Azelec cream is used for the treatment of mild to moderate inflammatory acne vulgaris on the skin.
The active ingredient in Azelec, azelaic acid, exhibits antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis. This antimicrobial effect may be attributed to the suppression of microbial cellular protein production. Additionally, azelaic acid may normalize keratinization, leading to an anticomedonal (reduction of blackheads and whiteheads) effect.
A thin layer of Azelec should be gently and thoroughly massaged into the affected areas on clean, dry skin twice daily – in the morning and evening. After application, hands should be washed. This medication is not established as safe and effective for use in pediatric patients under 12 years of age unless directed by a physician.
Drug-Drug Interaction: Azelec Cream may interact with other medications used to treat acne (like isotretinoin), drugs for managing fluid retention (such as spironolactone), injectable antibiotics, immunosuppressive drugs, and medications used to alleviate itching. It's important to inform your healthcare provider about all the medications you are taking to avoid potential interactions.
Drug-Food Interaction: No established interactions with food have been reported for Azelec Cream.
Drug-Disease Interaction: Before starting Azelec Cream, it is crucial to provide your doctor with your medical history, including any prior skin infections or skin-related conditions. This information will help ensure the safe and effective use of the medication.
Individuals who have displayed hypersensitivity to any of the components of azelaic acid should avoid its use.
Azelec falls under Pregnancy Category B according to the FDA. Its use during pregnancy should be reserved for situations where it is deemed absolutely necessary. If used by a breastfeeding mother, it should be done with caution.
Azelec is intended for external use only. In case of contact with the eyes, thorough rinsing with plenty of water is recommended. If eye irritation persists, medical attention should be sought.
Store Azelec in a cool, dry place protected from light. Keep all medicines out of reach of children.
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