Benoxiclin Gel

✔️ Uses of Benoxiclin Gel

• Treats mild to moderate acne in adults and adolescents (aged 12 years or older)

✔️ How does Benoxiclin Gel work?

Benoxiclin Gel is an effective treatment for acne in both adults and adolescents. It contains two active ingredients, clindamycin and benzoyl peroxide, which work together to combat acne-causing bacteria and improve the condition of the skin.

Clindamycin acts by inhibiting the growth and multiplication of the bacteria responsible for acne. Targeting these bacteria, it helps reduce inflammation and prevent the formation of new acne breakouts.

Benzoyl peroxide, on the other hand, has multiple actions. It helps open up clogged pores by removing dead skin cells and excess oil. This helps to prevent the accumulation of bacteria and debris that contribute to acne breakouts. Additionally, benzoyl peroxide can also reduce the production of oil in the skin over time, further controlling acne.

By combining these two ingredients, Benoxiclin Gel provides a comprehensive approach to treating acne. It not only addresses the underlying bacterial infection but also helps to unclog pores and reduce oiliness, leading to improved skin health and a reduction in acne breakouts.

✔️ Side Effects of Benoxiclin Gel

• Dry skin
• Skin peeling
• Skin itching
• Skin redness
• Pain or burning sensation of the skin

✔️ Quick Suggestions:

Here are some instructions to follow while using Benoxiclin Gel for acne treatment:

• Wash your face with mild soap and lukewarm water. Avoid very hot or cold water as it may worsen acne. Stick to your regular washing routine, not more frequently.
• Apply a thin layer of the gel on the affected area. You may experience minor burning, stinging, or irritation upon application. If these symptoms persist, inform your doctor.
• Avoid contact with your eyes, nose, or mouth. If the gel accidentally comes into contact with these areas, rinse them thoroughly with water.
• Your doctor may recommend using non-antibiotic skin preparations along with Benoxiclin Gel to prevent acne resistance. Follow your doctor's advice regarding their usage.
• Improvement in acne may take some time, so be patient and use the gel every day as prescribed. If your skin doesn't improve after completing the recommended duration, consult your doctor.
• Avoid excessive sun exposure while using Benoxiclin Gel as it can make your skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen when going outdoors.
• After exercising, take a shower immediately as sweat can irritate acne.
• Wash your hair regularly and prevent hair from falling across your face.
• Remove makeup completely before going to bed.
• Avoid using harsh soaps, skin cleansers, shampoos, hair removers or waxes, hair coloring or permanent chemicals, detergents, and rough fabrics that may irritate your skin.
• Refrain from squeezing, popping, or picking at your acne as it can worsen the condition and lead to permanent scarring.
• If your acne persists or worsens after using Benoxiclin Gel for one month, it is advised to consult a dermatologist.

✔️ Indication of Benoxiclin Gel

Clindamycin 1% + Benzoyl Peroxide 5% (BenzaClin) is a combination gel indicated for use twice daily, or as directed by a physician, for the topical treatment of inflammatory and noninflammatory lesions of acne vulgaris.

✔️ Pharmacology

Clindamycin is a type of antibiotic that is derived from lincomycin. It works by inhibiting the synthesis of proteins in bacteria. Specifically, it binds to the 50S ribosomal subunits of bacteria, which prevents the bacteria from carrying out essential processes like transpeptidation and translocation.

Benzoyl peroxide, on the other hand, is known for its strong oxidizing activity. It has moderate keratolytic (exfoliating) properties and also exhibits antibacterial effects. Benzoyl peroxide effectively kills Propionibacterium acnes, the bacteria responsible for causing acne vulgaris.

When used in combination, clindamycin, and benzoyl peroxide provide a dual action against acne. Clindamycin helps to inhibit bacterial growth, while benzoyl peroxide exfoliates the skin and kills acne-causing bacteria. This combination therapy is effective in treating acne vulgaris caused by Propionibacterium acnes.

✔️ Dosage & Administration of Benoxiclin Gel

Always follow the instructions provided by your physician when using Benoxiclin Gel. It should only be used externally. Before applying the gel, clean the affected area of the skin with warm water and pat it dry. Then, apply a thin layer of Benoxiclin Gel to the affected area. Allow the medicine to completely dry on your skin before using any cosmetics or makeup products.

Avoid using cosmetics or makeup products before applying Benoxiclin Gel. It is important to check the label of the medicine or consult your doctor to determine the appropriate quantity of the gel that should be applied.

If you experience skin dryness or irritation after using Benoxiclin Gel, contact your doctor. Make sure to avoid contact with the gel with your eyes, ears, nose, or mouth.

The duration of therapy with Benoxiclin Gel will be determined by your doctor based on your specific condition.

✔️ Interaction

It is important to inform your doctor about any medications you are taking, including vitamin A-related drugs known as retinoids (such as isotretinoin, bexarotene, adapalene, and tazarotene), skeletal muscle relaxants (such as atracurium, cisatracurium, doxacurium, pancuronium, rocuronium, rapacuronium, vecuronium, pipecuronium, mivacurium, metocurine, tubocurarine, succinylcholine), and antibiotics (such as dapsone). Your doctor needs to be aware of these medications to ensure there are no potential interactions or adverse effects when using Benoxiclin Gel.

Regarding drug-food interactions, no specific interactions have been reported for Benoxiclin Gel.

If you have intestine problems, ulcerative colitis, or a history of severe diarrhea caused by any antibiotic medicine, it is important to inform your doctor before using Benoxiclin Gel. Your doctor can assess your condition and determine if the gel is suitable for you or if any additional precautions need to be taken.

Always follow your doctor's instructions and inform them about your medical history and current medications to ensure the safe and effective use of Benoxiclin Gel.

✔️ Contraindications

Clindamycin, lincomycin, benzoyl peroxide, or any of the components found in their formulations should not be used if you have a known hypersensitivity or allergic reaction to them. If you have experienced an allergic reaction to any of these substances in the past, it is important to avoid using them.

Additionally, if you have a history of regional enteritis (Crohn's disease), ulcerative colitis, pseudomembranous colitis, or antibiotic-associated colitis, it is generally not recommended to use clindamycin, lincomycin, or any medications containing these substances. These conditions may be exacerbated by the use of these antibiotics, and they can potentially lead to further complications.

✔️ Pregnancy & Lactation

The use of Benoxiclin Gel during pregnancy is classified as category C. This means that animal studies have shown adverse effects on the fetus, but there are no adequate and well-controlled studies in humans. The potential benefits of using the medication in pregnant women may outweigh the potential risks.

It is not known if Benoxiclin Gel is excreted in breast milk, and its use is not advised during lactation. It is recommended to consult with a healthcare professional before using Benoxiclin Gel if you are pregnant or breastfeeding to evaluate the potential risks and benefits in your specific situation.

✔️ Precautions & Warnings

• Inform your doctor if you are allergic to Benoxiclin Gel or any other medications.
• Do not apply the gel to cuts, open wounds, broken skin, sunburnt skin, or sensitive skin areas.
• Do not swallow Benoxiclin Gel 20gm. If accidental swallowing occurs, consult a doctor.
• Avoid contact with the gel with the nose, ears, mouth, or eyes. If contact occurs, thoroughly rinse with warm water.
• Protect your skin from excessive sun exposure while using Benoxiclin Gel, as it can make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen when going outside.
• Inform your doctor if you are pregnant or breastfeeding before using Benoxiclin Gel.
• Do not use Benoxiclin Gel for more than 12 weeks continuously unless advised by your doctor.
• Avoid using excessive amounts of the gel or using it for a longer duration than prescribed, as it may increase the risk of side effects such as redness, irritation, skin peeling, or discomfort.
• If you have intestinal problems, ulcerative colitis, or a history of severe diarrhea caused by any antibiotic medication, inform your doctor before using Benoxiclin Gel.

It is important to adhere to these guidelines to ensure safe and effective use of the medication. If you have any concerns or questions, consult your doctor or healthcare provider.

✔️ Storage Conditions

Keep the temperature below 30°C. Keep out of children's reach.