Clindacin Lotion 25ml

✔️ Uses of Clindacin Lotion

• Acne

✔️ How does Clindacin Lotion work?

Clindamycin inhibits bacterial protein synthesis by binding to the ribosomal 50S subunit.

✔️ Side Effects of Clindacin Lotion

May cause adverse effects such as vaginitis, headaches, dizziness, gastrointestinal symptoms (heartburn, nausea, vomiting, diarrhea), dermatological symptoms (rash, exanthema), and hypersensitivity reactions like urticaria.

✔️ Quick Suggestions:

• Apply a thin layer on clean, dry, unbroken skin affected by acne.
• Avoid sun exposure; use sunscreen regularly.
• For external use only. Wash and dry the affected area before applying a thin layer of the lotion.
• Avoid contact with eyes, nose, or mouth. Rinse with water if accidental contact occurs.
• It may take several weeks for improvement. Do not stop using it as soon as symptoms lessen.
• Inform your doctor about any bowel issues, antibiotic-related bloody diarrhea, or other skin medications.
• Consult if pregnant or breastfeeding.

✔️ Indication

• Clindacin Lotion is an antibiotic used to treat acne, targeting the bacteria causing pimples on the face, chest, or back.
• Also prescribed for skin conditions like rosacea, periorificial dermatitis, folliculitis, stasis, chronic lymphedema, familial pemphigus, and dermal ulcers.

✔️ Pharmacology

• Antibiotic Properties: Clindamycin is a lincosamide antibiotic effective against microorganisms susceptible to it.
• Mechanism of Action: Binds to the 50s subunit of the bacterial ribosome, preventing the initiation of protein synthesis.
• Spectrum: Effective against gram-positive cocci (Staphylococcus aureus, Staphylococcus epidermidis, Streptococci, Pneumococci) and gram-negative anaerobic bacteria.

✔️ Dosage & Administration of Clindacin Lotion

1. Gently wash the face or affected area with warm water or soap.
2. After the skin is completely dried (approximately 30 minutes later), apply a thin film of Clindamycin lotion to the entire affected area twice daily.
3. Avoid washing the applied area within 3 hours.
4. A noticeable improvement is usually seen after about 6 weeks, with 8 to 12 weeks of treatment for maximum benefit.

✔️ Interaction

• May enhance neuromuscular blocking agents.
• Antagonizes effects of parasympathomimetics.
• Competitively inhibits the effects of certain antibiotics.
• May affect coagulation tests when used with warfarin or similar drugs.

✔️ Contraindications

Contraindicated in patients with hypersensitivity to clindamycin.

✔️ Pregnancy & Lactation

Safety during pregnancy is uncertain. Use caution during nursing as it is not known if Clindamycin is eliminated in breast milk after topical application.

✔️ Precautions & Warnings

• Avoid use in the mouth, eyes, or vaginal area.
• Avoid sunlight and sunlamps; use sunscreen regularly.

✔️ Storage Conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.