Amarin 45.5mg/2ml Injection 1pc

Uses of Amarin 45.5mg/2ml Injection

How does Amarin 45.5mg/2ml Injection work?

Side Effects of Amarin 45.5mg/2ml Injection

• Sedation (drowsiness)

Quick Suggestions:

• Amarin 45.5mg/2ml Injection has the potential for abuse due to CNS (central nervous system) stimulating effects of antihistamines. Therefore take Amarin 45.5mg/2ml Injection only as prescribed by the doctor.
• It is effective in controlling symptoms of cold tearing of eyes, nasal stuffiness, and nasal discharge.

Motion/Travel Sickness:

Motion or travel sickness occurs when a person feels sick while traveling, typically due to the repetitive motion of a vehicle or any movement that disrupts the inner ear. The disturbance in the inner ear leads to symptoms such as nausea, vomiting, and dizziness.

Allergy:

An allergy is a condition where the immune system reacts abnormally to foreign substances such as pollen, dust mites, mold spores, food, pet dander, insect stings, and certain medications. Common types of allergies include drug allergy, food allergy, contact dermatitis, latex allergy, allergic asthma, seasonal allergies, animal allergies, and anaphylaxis (a severe allergic reaction). Symptoms can vary from mild, like rashes, hives, itching, watery eyes, and a runny nose, to severe reactions that can be life-threatening.

Meniere's Disease:

Meniere's disease is a disorder of the inner ear that causes episodes of vertigo (a spinning sensation), which can result in severe nausea and loss of balance. Other symptoms include hearing loss, tinnitus (a ringing sound in the ear), and a feeling of pressure or fullness in the ear.

Pharmacology

Pheniramine, the active ingredient in Avil, competes with histamine for the H1 receptor, acting as an inverse agonist. This reduces itching, vasodilation, and capillary leakage, leading to less redness and edema. In the CNS, inverse agonism of the H1 receptor is responsible for sedation, a common effect of first-generation antihistamines like pheniramine.

Dosage & Administration of Amarin 45.5mg/2ml Injection

Injection Solution: For adults and young people aged 12 years or over, 1.0-2.0 ml IV/IM once or twice daily. For children, the dosage varies based on age and body weight. 

Amarin 45.5mg/2ml Injection will be administered to you only by a doctor or a nurse into a vein as a slow intravenous injection or into a muscle (intramuscularly). To infants and children up to 12 years of age, Amarin 45.5mg/2ml Injection will be given intramuscularly. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and general health condition.  

Before receiving Amarin 45.5mg/2ml Injection inform your doctor if you have received or have taken any of the following medicines:

• Monoamine oxidase inhibitors (MAOIs) such as isocarboxazid, and phenelzine (used to manage depression)
• Zolpidem, triazolam, alprazolam, diazepam (used to manage sleep disturbances and anxiety)
• Atropine (used to manage low heart rate and reduce bronchial secretions)
• Other anticholinergic drugs (used to manage nausea and vomiting due to motion sickness (Ex. scopolamine) and Parkinson’s disease (Ex. benztropine))

Contraindications

• Hypersensitivity to pheniramine or any ingredient in the formulation.
• Symptomatic prostatic hypertrophy.
• Patients receiving MAO-inhibitor therapy.
• Newborn and premature infants.

Pregnancy & Lactation

Pregnancy Category A: Use only if strictly indicated.

Precautions & Warnings

• Do not take Pheniramine Maleate if you are allergic to any of its components.
• Avoid using Pheniramine Maleate if you have prostatic hypertrophy (enlarged prostate gland).
• Do not use Pheniramine Maleate if you are currently taking MAO inhibitors.
• Inform your doctor if you have conditions such as narrow-angle glaucoma, asthma, severe cardiovascular disease, or kidney, or liver problems.
• Consult your doctor before using Pheniramine Maleate if you are pregnant or breastfeeding.
• This medication may cause drowsiness. Only drive or operate machinery if you are fully alert.
• Pheniramine Maleate is not recommended for children under 5 years of age, newborns, or premature infants.
• The anti-emetic effect of Pheniramine Maleate may mask symptoms of other conditions. Always keep your doctor informed about your full medical history.

Storage:

Store in a cool, dry place protected from light. Keep out of reach of children. Use only as prescribed by a physician.