Type: syrup. Generic Name:Pheniramine maleate 15mg/5ml Manufacturer/Distributor: Sanofi-aventis
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Avil is an antiallergic medication. It treats symptoms of severe allergic reactions due to insect bite/sting, certain medicines, hives (rashes, swelling etc). Avil is given as an injection into veins or muscles under the supervision of a doctor. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Sleepiness is the most common side effect of this medicine. Avoid driving or attention-seeking activity. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. In some cases, it may cause dryness of mouth, so it is advised to drink more water, always carry sugar candy or maintain oral hygiene. Before taking this medicine, let your doctor know if you have glaucoma or have asthma issues or have high blood pressure. Inform your doctor if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment.
Uses of Avil
Side effects of Avil
Common
How to use Avil
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Avil works
Avil is an antiallergic medication. It works by blocking the action of a chemical messenger (histamine). This relieves symptoms of severe allergic reactions due to insect bite/sting, certain medicines, hives (rashes, swelling etc).
What if you forget to take Avil?
If you miss a dose of Avil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Brief Description
Indication
Allergic conditions, Motion sickness, Allergic conjunctivitis, Allergic rhinitis
Administration
Should be taken with food. Take after meals.
Adult Dose
Oral Allergic conditions Adult: Syrup: 15-30 mg bid or tid. Tablet: Up to 45 mg tid. Max: 3 mg/kg/day. Elderly: Syrup: 15-30 mg bid or tid. Tablet: Up to 45 mg tid. Max: 3 mg/kg/day. Prophylaxis of motion sickness Adult: Syrup: 15-30 mg bid or tid. Tablet: Up to 45 mg tid. Max: 3 mg/kg/day. Take 1st dose at least 30 min before travelling.
Child Dose
Oral Allergic conditions Child: Tablet 5-10 yr: Half a 45-mg tablet up to tid; Tablet: Up to 45 mg tid. >10 yr: Syrup: 15-30 mg bid or tid. Max: 3 mg/kg/day. Prophylaxis of motion sickness Child: As maleate: 5-10 yr: Half a 45-mg tablet up to tid; >10 yr: Syrup: 15-30 mg bid or tid. Tablet: Up to 45 mg tid. Max: 3 mg/kg/day. Take 1st dose at least 30 min before travelling.
Contraindication
Symptomatic prostatic hypertrophy; neonates and premature infants.
Mode of Action
Pheniramine is an alkylamine derivative with histamine H1-receptor antagonist effects. It also has anticholinergic and moderate sedative effects.
Precaution
May impair ability to drive or operate machinery. Has potential for abuse. Narrow angle glaucoma, asthma or severe CV disease. Antiemetic effect may mask signs of other conditions. Pregnancy and lactation. Elderly.
Side Effect
Sedation. Hypersensitivity reactions. Lassitude, dizziness, tinnitus, inability to concentrate, incoordination, irritability, insomnia and tremors. Nausea, vomiting, diarrhoea, colic, epigastric pain, anorexia, dryness of mouth and constipation. Urinary retention. Palpitations, headache. Blurred vision, increased intraocular pressure. Muscular weakness. Rarely, blood dyscrasias e.g. agranulocytosis, haemolytic anaemia.
Interaction
May mask ototoxicity produced by aminoglycoside antibiotics. Potentially Fatal: Potentiation of CNS depression by alcohol, sedatives, opioids, barbiturates, hypnotics, narcoleptics. May increase antimuscarinic effect of MAOIs, atropine and TCAs.
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