Cortan 10mg Tablet 100Pcs

✔️ Uses of Cortan 10

• Treatment of Severe Allergic Reactions
• Treatment of Allergic Conditions
• Treatment of Rheumatic Disorder
• Treatment of Skin Disorders
• Treatment of Eye Disorders
• Treatment of Nephrotic Syndrome

✔️ How Cortan 10 works

Cortan 10 is a steroid that works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

✔️ Side Effects of Cortan 10

• Weight gain
• Indigestion
• Fast heartbeat
• Increased appetite
• Aggression or anger
• Decreased urine output
• Problems sleeping (insomnia)
• Feeling restless
• Sweating a lot
• Mild mood changes
• Osteoporosis (weak and brittle bones)
• Swelling due to fluid accumulation
• High blood pressure
• Thinner skin
• Impaired wound healing
• Muscle wasting

✔️ Quick Suggestions:

• Cortan 10mg Tablet helps treat inflammation, severe allergies, relapses of chronic diseases, and several other medical conditions that call for either immune system suppression or inflammatory suppression.
• Avoid using it more frequently or for longer than your doctor has prescribed.
• Take Cortan 10mg Tablet with meals to prevent gastric distress.
• Stress has an impact on the immune system and increases the likelihood of being sick. Regular exercise, meditation, deep breathing, and the use of progressive muscle relaxation methods are all effective ways to reduce stress.
• Cortan 10mg Tablet may impair your ability to fight against infections. If you have any infection-related symptoms, such as a fever or sore throat, let your doctor know.
• When you first start using Cortan 10mg Tablet, side symptoms including mood swings or digestive issues may occur. If this affects you, let your doctor know.
• Without first seeing your doctor, do not abruptly stop taking Cortan 10mg Tablet as this might make your symptoms worse.

✔️ Indications of Cortan 10mg Tablet

Prednisolone is Indicated-

• For the treatment of inflammatory and autoimmune diseases, including: (including severe allergic reactions)
• Inflammation can damage the lungs, including asthma, blood vessels and the heart, the colon, and kidneys, muscles, and joints, rheumatoid arthritis, and the eyes and brain system.
  malignancies, infections, and skin conditions (such as leukemia, lymphoma, and myeloma)
• To avoid organ rejection the following transplant
• When the body is unable to produce enough natural steroids on its own, it increases steroid levels.
• Excessive body calcium levels must be treated.

✔️ Pharmacology

Prednisolone is a synthetic adrenocortical drug that functions similarly to glucocorticoids. The Phospholipase A2 enzyme, which produces inflammatory mediators like leukotrienes, SRS-A, and prostaglandins, is inhibited by prednisolone. Prednisolone is quickly and completely absorbed from the GI tract after oral ingestion. Prednisolone has a half-life of 2 to 4 hours before it is excreted and is 70–90% protein-bound in the plasma. The liver is where it is primarily processed, and urine is where it is eliminated.

✔️ Dosage and Administration

Adult-

Allergic Conditions:

• Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime.
• Day 2: 5 mg PO before breakfast, after lunch, and after dinner, and 10 mg at bedtime.
• Day 3: 5 mg PO before breakfast, after lunch, after dinner, and at bedtime.
• Day 4: 5 mg PO before breakfast, after lunch, and at bedtime.
• Day 5: 5 mg PO before breakfast and at bedtime.
• Day 6: 5 mg PO before breakfast.

Nephrotic Syndrome:

• Initial: 2 mg/kg/day (maximum 80 mg/day) in divided doses 3 to 4 times/day until urine is protein-free for 3 consecutive days (maximum: 28 days); followed by 1 to 1.5 mg/kg/dose given every other day for 4 weeks.
• Maintenance dose: 0.5 to 1 mg/kg/ dose given every other day for 3 to 6 months.

Anti-inflammatory: 

• 5 to 60 mg per day in divided doses 1 to 4 times/day.

Acute Asthma: 

• 40-60 mg/day PO in a single daily dose or divided q12 hr for 3-10 days.

Pediatric-

Asthma:

• 1 year: Acute: 10 mg orally every 12 hours. Maintenance: 10 mg orally every other day.
• 1 to 4 years: Acute: 20 mg orally every 12 hours. Maintenance: 20 mg orally every other day.
• 5 to 12 years: Acute: 30 mg orally every 12 hours. Maintenance: 30 mg orally every other day.
• 12 years: Acute: 40 mg orally every 12 hours. Maintenance: 40 mg orally every other day.

Anti-inflammatory: 

• 0.05 to 2 mg/kg/day divided 1 to 4 times/day.

Immunosuppression: 

• 0.05 to 2 mg/kg/day divided 1 to 4 times/day.

Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, Griseofulvin, Mitotane, Phenylbutazone, Phenytoin, Primidone, and Rifampin all decrease the effectiveness of prednisolone. The amount of potassium in the blood is decreased by prednisolone. If hypokalemia occurs, digitalis may cause cardiac arrhythmias. Care must be taken when administering vaccinations.

✔️ Interaction of Cortan 10

Cortan 10mg Tablet may interact with drugs used to treat tuberculosis (such as rifampicin, and isoniazid), blood thinners (such as aspirin, and warfarin), antiepileptic medications (such as carbamazepine, phenobarbital, and phenytoin), anticholinergic drugs (such as amitriptyline), drugs used to treat myasthenia gravis (such as (e.g. amphotericin B).

Grapefruit and diets high in protein have negative interactions with Cortan 10mg Tablet. Cortan 10mg Tablet should not be used with it as a result.

Infections, stomach ulcers, ulcerative colitis (GI perforation), prematurity issues, tuberculosis, hyperadrenocorticism (presence of an excess of adrenocortical hormones), hyperlipidemia (high levels of fats in the blood), liver disease or kidney failure, myasthenia gravis (a disease that causes muscle weakness), diabetes, a recent vaccination, infections, prematurity problems, a recent vaccination, stomach ulcer.

✔️ Contraindications

Unless specific anti-infective therapy is used, systemic infections can occur. Intolerance to any ingredient Herpes simplex ocular because of potential perforation

✔️ Pregnancy & Lactation

Use of this medication during pregnancy is not advised unless it is deemed necessary by your doctor. Only when the predicted benefit to the mother outweighs any potential harm to the fetus should it be utilized. Breast milk contains corticosteroids, which may stunt development, obstruct the synthesis of endogenous corticosteroids, or have other negative consequences.

✔️ Precautions & Warnings

Vigilance is necessary for those who have diabetes, hypertension, psychiatric issues, osteoporosis, postmenopausal women, pregnancy, and chronic nephritis. Long-term Prednisolone usage may result in Cushing's syndrome, hyperglycemia, muscular weakness, heightened susceptibility to infection, sluggish wound healing, and psychiatric issues.

✔️ Storage Conditions

Store in a cool and dry place, protected from light. Keep out of the reach of the children.