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Fexofenadine Hydrochloride is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children. It is also indicated for the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.
Fexofenadine Hydrochloride is an antihistamine with selective peripheral H1-receptor antagonist activity. It is rapidly absorbed after oral administration and peak plasma concentration is reached in 2-3 hours. It does not appear to cross the blood brain barrier.
Seasonal Allergic Rhinitis-
Adults and children 12 years and older:
Children from 6 to 11 years:
Children from 2 to 11 years
Plasma concentration of Fexofenadine Hydrochloride have been increased when given with erythromycin or ketoconazole. Aluminium and magnesium hydroxide containing antacid reduces the absorption of Fexofenadine Hydrochloride.
Contraindicated in patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients.
Common side effects are headache, fatigue, drowsiness, nausea, dry mouth and gastrointestinal disturbances.
US FDA pregnancy category of Fexofenadine Hydrochloride is C. So, Fexofenadine Hydrochloride should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.
Caution should be exercised in elderly patient and patient with decreased renal function.
Non-sedating antihistamines
Store in a cold, dry, and light-protected location. Keep out of children's reach.
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