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Roxadex-IM/IV 5mg/ml Injection

Generic: Dexamethasone Sodium Phosphate

Type: Injection

Pack Size: 1 Pc

Roxadex Injection (Dexamethasone Sodium Phosphate) is a corticosteroid medicine that is used to reduce swelling associated with various conditions such as arthritis, allergic disorders, psoriasis, etc. It is also used for other conditions like adrenal hormonal insufficiency, certain types of anemia, cerebral edema, etc. 


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Discount Price: ৳ 30.72
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✅ Description:

Roxadex (Dexamethasone) Injection is a type of corticosteroid hormone that can be used to treat various medical conditions, including severe allergies, lung problems, blood disorders, skin diseases, and autoimmune disorders. It can also be used before and after surgery and is approved for the treatment of COVID-19 in patients who require oxygen therapy.

Roxadex Injection contains Dexamethasone, which has anti-inflammatory and immunosuppressive effects. It can relieve symptoms such as swelling and tenderness and calm the immune system, which is helpful for autoimmune diseases.

It is important to have this medication administered by a healthcare professional and not to self-administer. Some possible side effects include changes in mood or mental health, muscle weakness, increased appetite, irregular periods, vision problems, sleep issues, heartburn, nausea, and injection site pain or redness. Most side effects are not serious and will go away on their own, but if they persist or worsen, you should consult your doctor.

Before taking Roxadex Injection, inform your doctor if you are allergic to any of the ingredients or if you have a history of certain medical conditions. It is also important to let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding, as this medication can have effects on the fetus or infant. Additionally, it is important to disclose any other medications you are currently taking to avoid potentially harmful interactions.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while receiving Roxadex Injection as it may make you feel drowsier.


Pregnancy
CONSULT YOUR DOCTOR

Dexamethasone Sodium Phosphate Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

Roxadex Injection (Dexamethasone Sodium Phosphate Injection) is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Driving
UNSAFE

Roxadex Injection is unlikely to affect your ability to drive or handle any heavy tools or machines.


Kidney
CAUTION

Roxadex Injection should be used with caution in patients with kidney diseases. Therefore, consult your doctor before receiving it.


Liver
CAUTION

Roxadex Injection should be used with caution in patients with liver diseases. Therefore, consult your doctor before receiving it.

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✔️ Uses of Roxadex Injection
  • Treatment of Inflammatory conditions
  • Treatment of Autoimmune conditions
✔️ How Roxadex Injection works?

Roxadex Injection is a steroid medicine with anti-inflammatory and immune suppressant properties. It boosts your body with sufficient corticosteroid levels (cortisol, aldosterone) during deficient conditions and helps your body to function properly. It also reduces the release of certain chemicals (prostaglandins) in the body that causes inflammation, pain, irritation, and swelling. As a result, it reduces allergic and inflammatory conditions in the body.

✔️ Side Effects of Roxadex Injection
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Loss of vision or blurred vision
  • Black or tarry stools
  • Unusual tiredness and weakness
  • Headache
  • Impaired vision
  • Vertigo (spinning sensation)
  • Headache
  • Cataracts or feeling increased pressure in the eye
  • Thickening of the heart muscle
  • High blood pressure
  • Blood clots in the veins
  • Spinning sensation, increased sweating
  • Acne, skin rash, bruising
  • Nausea, stomach pain or discomfort, increased appetite
  • Changes in vision, feeling weak or tired, slow wound healing
  • Skin thinning
  • Dizziness
  • Sleeplessness
  • Agitation and anxiety
  • Acne
  • Hiccups (sudden inspiration or intake of air)
  • Heartburn
  • Peptic ulcer
  • Muscle weakness
  • Loss of muscle mass
  • Osteoporosis (loss of bone density)
  • Increased hair growth
  • Irregular menstrual periods
  • Easy bruising and bleeding
✔️ Quick Suggestions:
  • Roxadex helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
  • Do not use it more often or for longer than advised by your doctor.
  • Roxadex can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
  • Incorporating probiotic-rich foods into your diet can help strengthen your immune system's resistance to allergies. Foods that are high in quercetin, a flavonoid, such as apples, cherries, spinach, broccoli, and blueberries, are also beneficial. Including a variety of seasonal fruits, vegetables, whole grains, healthy fats, and fish in your daily diet can provide your body with the necessary nutrients to maintain a healthy immune system.
  • It is important to limit your intake of foods that may cause allergies, such as dairy products, soy, eggs, and nuts. Additionally, consuming too many foods high in sugar can aggravate inflammation and should be avoided.
  • Managing stress levels and maintaining a regular sleep schedule can also have positive effects on your immune system's response to allergies.
  • Side effects such as mood changes or stomach problems can happen when you start taking Roxadex. Inform your doctor if this bothers you.
  • Do not stop taking Roxadex suddenly without talking to your doctor first as it may worsen your symptoms.
✔️ Indication of Roxadex Injection

Roxadex Injection is used to treat the following disease conditions:

  • Adrenal insufficiency and its associated conditions
  • Bone and joint problems (Ex. rheumatoid arthritis, ankylosing spondylitis)
  • Skin and collagen disorders (Ex. Stevens-Johnson syndrome, psoriasis)
  • Eye problems (Ex. optic neuritis, uveitis, or iritis)
  • Respiratory tract diseases (Ex. asthma, tuberculosis, pneumonitis)
  • Blood cancer (leukemia), lymph cancer (lymphoma)
  • Anemia (low RBC count in the blood), thrombocytopenia (low platelet count in the blood)
  • Problems of bowel and gut (Ex. Crohn’s disease and ulcerative colitis)
  • Brain problems (Ex. tuberculous meningitis, cerebral edema)
  • Increased intracranial pressure
  • Heart inflammation (Ex. endocarditis)
  • Drug-induced hypersensitivity reactions
  • Allergic reactions (such as atopic dermatitis, allergic conjunctivitis, and allergic rhinitis)
  • High blood calcium levels caused due to cancer treatment
  • Protein loss via urine due to kidney problems
✔️ Pharmacology

Dexamethasone is a glucocorticoid that reduces inflammation by preventing white blood cell migration and reversing improved capillary permeability. It suppresses the normal response of the immune system.

✔️ Dosage of Roxadex Injection

Dexamethasone can be administered through IV, IM, or local injections. Infusion fluids can also be used to dilute the injections or inject them directly into the infusion line.

For IV injections, large doses should be given slowly over several minutes. Deep intramuscular injection is recommended to prevent subcutaneous adipose tissue atrophy. Intra-articular injections must be given under strict aseptic conditions as glucocorticoids decrease resistance to infection. Sodium chloride 0.9%, Anhydrous glucose 5%, Invert sugar 10%, Sorbitol 5%, Ringer's solution, Hartman's solution (Ringer-lactate), and other infusion fluids can be used to dilute Dexamethasone, which remains potent for at least 24 hours at room temperature and in daylight.

The dosage of Dexamethasone depends on the severity of the condition and the patient's response. For systemic therapy in adults, daily doses of 0.05-0.20 mg/kg body weight are usually sufficient. In emergencies, substantially higher doses are required. An initial dose of 10-20 mg IV is followed by 6 mg IV or IM every 6 hours until a satisfactory result is obtained. The dosage must then be gradually tapered off.

For local therapy, the recommended doses are 2-4 mg for large joints and 0.8-1 mg for small joints in intra-articular injections, 2-4 mg in intranasal injections, and 0.4-1 mg in tendon sheaths injections. The frequency of these injections may vary from every 3-5 days to every 2-3 weeks.

✔️ Administration of Roxadex Injection
  • Roxadex Injection will be given to you only by a doctor or a nurse into the vein, muscle, joints, or tendons depending upon the site of inflammation.
  • Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.
✔️ Interaction

It is important to inform your doctor about any medications that you are taking before receiving Roxadex Injection. This includes:

  • Aminoglutethimide or cyclophosphamide, which is used for treating cancer
  • Anticoagulants such as acenocoumarol, phenindione, and warfarin, which are used for blood thinning
  • Medicines used to treat bacterial infections, such as isoniazid, erythromycin, clarithromycin, and troleandomycin
  • Medicines used to treat diabetes, such as metformin and glipizide
  • Non-steroidal anti-inflammatory medicines, such as aspirin and ibuprofen, which are used for fever and pain relief
  • Medicines used to treat epilepsy, such as carbamazepine, phenytoin, and primidone
  • Ephedrine, which is used for cough
  • Medicines used to treat HIV infections, such as ritonavir and cobicistat
  • Medicines used to treat fungal infections, such as ketoconazole, amphotericin B, and itraconazole
  • Diuretics, such as furosemide, chlorothiazide, and hydrochlorothiazide, are used to treat edema and hypertension
  • Rifampicin and rifabutin, which are used to treat tuberculosis
  • Carbenoxolone, which is used to treat mouth ulcers
  • Anticholinergic medicines used to treat myasthenia gravis, such as distigmine and neostigmine
  • Acetazolamide, which is a medicine used to treat glaucoma or edema

Your doctor may need to adjust your medication doses or switch you to a different medication to avoid interactions with Roxadex Injection.

✔️ Contraindications
  • Gastric and duodenal ulcers.
  • Systemic and ophthalmic fungal infections.
  • Viral infections, e.g., varicella and herpes genitals infections. Viral infections of the eye.
  • Glaucoma.
  • Hypersensitivity to corticosteroids
✔️ Pregnancy & Lactation

When taken during pregnancy, corticosteroids can have negative effects on fetal development, including orofacial clefts, growth restriction, and decreased birth weight. It is recommended that females of reproductive potential undergo pregnancy testing before starting treatment and use effective contraception during treatment and for at least one month after the final dose. In some patients, steroids may affect male fertility by increasing or decreasing sperm motility and number. In lactating women, systemically administered corticosteroids can be present in breast milk and may interfere with the growth or production of natural corticosteroids in the infant. As a result, it is advised that women do not breastfeed during treatment and for 2 weeks after the last dose.

✔️ Precautions & Warnings
  • Before using Roxadex Injection, inform your doctor if you are allergic to any of the components of this medicine or other steroid drugs.
  • Additionally, let your doctor know if you have received any live virus vaccines or have any medical conditions such as fungal infections, amoebiasis, myasthenia gravis, peptic ulcer, osteoporosis, psychoses, eye infections, glaucoma, mental health conditions, TB, bacteremia, joint, liver, kidney, or heart problems, or septic arthritis caused by gonorrhea or tuberculosis.
  • If you are pregnant, planning to become pregnant, or breastfeeding, you should discuss this with your doctor before using this medicine.
  • Seek immediate medical attention if you experience mood changes, depression, or strange thoughts while using Roxadex Injection.
✔️ Storage Conditions

Do not freeze. Store in a cool and dry place away from sunlight. Keep medicines out of the reach of children

Frequently Asked Questions (FAQ)

A corticosteroid medication called Roxadex Injection is used to treat adrenal insufficiency. It can also be used to treat a variety of inflammatory auto-immune disease disorders that affect the skin, collagen, bones and joints, brain, stomach, eyes, and other organs and systems. Additionally, it boosts urine production and stops kidney disease patients from losing protein through the urine.

Yes. Roxadex Injection is corticosteroid used to treat problems of adrenal gland and various allergic, hypersensitivity and inflammatory autoimmune disease conditions.

The time taken by Roxadex Injection to control the disease may vary from person-to-person depending upon the dose of dexamethasone and disease severity.

Patients with severe viral or fungi infections shouldn't use Roxadex Injection. Additionally, patients with bone issues, bone infections, mental illnesses, or those who have a family history of these conditions should not use it.

Roxadex Injection may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before receiving Roxadex Injection as a precaution.

Roxadex Injection should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. Therefore, consult your doctor for advice before receiving it.

For the treatment of coronavirus disease 2019 (COVID-19) in adults and children (12 years of age and older with a body weight of at least 40 kg) who require supplementary oxygen therapy, dexamethasone 8 mg Injection 2 ml has been authorized.

Before taking any new medication, it is important to inform your healthcare provider about all the prescription and over-the-counter medications you are currently taking, including anticoagulants. Dexamethasone can interact with anticoagulants, which can increase the risk of bleeding. Your doctor may need to adjust the dosage of your anticoagulant medication or closely monitor you for signs of bleeding if you are taking Dexamethasone 8 mg Injection 2 ml therapy. It is essential to follow your doctor's instructions and not make any changes to your medication without consulting them first.
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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