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Sarinex D (2.5mg + 120mg) Tablet
Sarinex D (2.5mg + 120mg) Tablet is used for Allergic rhinitis, Itching, Sneezing, Watery eyes, Runny nose, Hives, Skin rash, Common cold, Nasal congestion
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✅ Description:
Sarinex D (2.5mg + 120mg) Tablet is indicated for the relief of symptoms associated with allergic rhinitis, such as itching, sneezing, watery eyes, runny nose, hives, skin rash, common cold, and nasal congestion.
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✔️ Dosage & Administration of Sarinex D (2.5mg + 120mg) Tablet
May be taken with or without food. Swallow whole; do not chew, break, or crush.
Adult Dose
- PO: Adults: 1 tablet (2.5 mg desloratadine/120 mg pseudoephedrine) every 12 hours. 1 tablet (5 mg desloratadine/240 mg pseudoephedrine) every 24 hours.
- Hepatic Impairment: Not recommended.
Child Dose
- PO: Child (12 years or older): 1 tablet (2.5 mg desloratadine/120 mg pseudoephedrine) every 12 hours. 1 tablet (5 mg desloratadine/240 mg pseudoephedrine) every 24 hours.
- Renal Dose: Not recommended.
✔️ Side Effect of Sarinex D (2.5mg + 120mg) Tablet
Desloratadine may cause fever, irritability, headache, diarrhea, cough, upper respiratory tract infection, pharyngitis, dry mouth, myalgia, emotional lability, erythema, maculopapular rash, dizziness, fatigue, somnolence, urinary tract infection, dyspepsia, insomnia, and dysmenorrhea. Pseudoephedrine side effects may include CNS effects, insomnia, arrhythmia, hypotension, tachycardia, rash, urticaria, anorexia, xerostomia, dysuria, polyuria, nausea, vomiting, and ischemic colitis.
✔️ Mode of Action
Desloratadine is a long-acting, non-sedating, selective peripheral histamine H1-receptor antagonist. Pseudoephedrine acts as both an α- and β-adrenergic receptor agonist, causing vasoconstriction and bronchial relaxation.
✔️ Interaction
Potential increase in plasma concentrations with drugs affecting hepatic microsomal enzymes (e.g., azithromycin, cimetidine, erythromycin, fluoxetine, ketoconazole). Increased risk of hypertension and arrhythmias with cardiac glycosides, quinidine, or TCAs. Increased risk of vasoconstrictor effects with ergot alkaloids or oxytocin. Co-administration with MAOIs may cause hypertensive crisis. Interaction with anesthetics and antihypertensive agents.
✔️ Contraindication
Hypersensitivity.
✔️ Pregnancy Category
Desloratadine: Limited data in pregnant women; use only if needed. Pseudoephedrine: The majority of studies found no association with an increased risk of congenital anomalies. Use during lactation may decrease milk production and cause irritability in infants.
✔️ Precaution
Severe renal or hepatic failure; children under 6 months, elderly, epilepsy, pregnancy, and lactation. Pseudoephedrine concentrates in breast milk; use caution during lactation.
✔️ Storage Conditions:
Store in a cool, dry place, protected from light.
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