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Indications of Tinabil Tablet
Bilastine is used to treat allergic rhino-conjunctivitis (seasonal and perennial) and urticaria symptomatically.
Pharmacology of Tinabil Tablet
Bilastine may be a non-sedating, long-acting histamine adversary with particular fringe H 1 receptor opponent liking and no fondness for muscarinic receptors. Bilastine represses histamine-induced wheal and flare skin responses for 24 hours taking after single dosages.
Dosage & Administration of Tinabil Tablet
Adults & adolescents (12 years of age and over): 20 mg tablet once daily for symptomatic relief of allergic rhinitis, urticaria and allergic rhinoconjunctivitis. The maximum recommended daily dose is 20 mg Bilastine (1 tablet) and should not be exceeded. If a dose is missed, the next scheduled dose should be taken. An extra dose should not be taken. 20 mg Bilastine tablet (1 tablet) once daily should be swallowed with water on an empty stomach to achieve optimal exposure to Bilastine.
Children between 6 to 11 years: 10 mg mouth dissolving tablet for the symptomatic relief of allergic rhinitis, allergic rhinoconjunctivitis and urticaria. The Mouth dissolving tablet is for oral use only. It should be placed in the mouth. It will disperse rapidly in saliva and can be easily swallowed. Alternatively, the mouth dissolving tablet can be dispersed in a tea spoon of water before being swallowed by the children. The maximum recommended daily dose for children in between 6 to 11 years is 10 mg Bilastine mouth dissolving tablet (1 tablet) and should not be exceeded. If a dose is missed, the next scheduled dose should be taken. An extra dose should not be taken.
Children between 2 to 11 years: 4 ml once daily.
Interaction of Tinabil Tablet
Concomitant admissions of Bilastine and Ketoconazole or Erythromycin or Diltiazem expanded C max of Bilastine. The psychomotor execution after concomitant admissions of liquor and Bilastine was comparable to that watched after admissions of liquor and fake treatment. Concomitant admissions of Bilastine and Lorazepam 3 mg for 8 days did not potentiate the depressant CNS impacts of Lorazepam.
Contraindications
Bilastine is not recommended for people who are hypersensitive to the active ingredient or any of the tablet's excipients.
Side Effects of Tinabil Tablet
There are no or limited amount of data from the use of Bilastine in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity, parturition or postnatal development. As a precautionary measure, it is preferable to avoid the use of Bilastine during pregnancy. The excretion of Bilastine in milk has not been studied in humans. A decision must be made taking into account the benefit of breast-feeding for the child and the benefit of Bilastine therapy for the mother.
Pregnancy & Lactation
There are no or constrained sum of information from the utilize of Bilastine in pregnant ladies. Creature considers don't show coordinate or circuitous hurtful impacts with regard to regenerative poisonous quality, parturition, or postnatal advancement. As a prudent degree, it is ideal to dodge the utilization of Bilastine during pregnancy. The excretion of Bilastine in the drain has not been examined in people. A choice must be made taking into consideration the advantage of breastfeeding for the child and the good thing about Bilastine treatment for the mother.
Precautions & Warnings
Co-administration of Bilastine and P-glycoprotein inhibitors (e.g. Ketoconazole, Erythromycin, Cyclosporine, Ritonavir or Diltiazem) ought to be dodged in patients with direct or extreme renal disability.
Storage Conditions
Keep below 30°C temperature, protected from light and moisture. Keep out of reach of children.
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