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Bilastine/Tinabil 20 is an antihistamine used to treat allergic symptoms such as itching, swelling, and rashes. It is most effective when taken one hour before or two hours after meals. Follow your doctor’s advice regarding the dose and duration of the treatment.
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✅ Description:
Bilastine, the active ingredient in Tinabil, is a potent, selective, and non-sedating antihistamine. It works by blocking H1 receptors with high affinity—three times higher than cetirizine and five times higher than fexofenadine. Even at high doses, Bilastine does not interact with over 30 other receptors, including muscarinic, serotonergic, dopaminergic, and noradrenergic receptors, or other histamine receptor subtypes (H2, H3, H4).
It has a strong safety profile and excellent pharmacokinetic characteristics. Bilastine does not require metabolic activation and is primarily excreted through feces (66.35%) and urine (28.31%).
Tinabil is used for the symptomatic treatment of:
- Allergic rhino-conjunctivitis (both seasonal and perennial).
- Urticaria (hives).
Additionally, it helps alleviate symptoms of hay fever, such as sneezing, itchy and runny nose, nasal congestion, and red, watery eyes.
Use this medication only under the guidance of a registered physician.
Safety Advices
Alcohol
UNSAFE
Use caution when consuming alcohol with Tinabil 20, as it may increase drowsiness. Consult your doctor for advice.
CONSULT YOUR DOCTOR
Limited information is available about the use of Tinabil 20 during pregnancy or breastfeeding. Please consult your doctor for guidance.
Driving
CAUTION
It is not clear if Tinabil 20 affects your ability to drive. Avoid driving or operating heavy machinery if you feel drowsy or unable to concentrate.
Kidney
SAFE IF PRESCRIBED
Tinabil 20 should be used cautiously in patients with kidney disease. Dose adjustments may be required. Consult your doctor.
Liver
SAFE IF PRESCRIBED
Limited data is available on the use of Tinabil 20 in patients with liver disease. Consult your doctor for further guidance.
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✔️ Uses of Tinabil 20
- Nasal congestion
- Urticaria (hives)
- Allergic symptoms, such as itching, swelling, and rashes
✔️ How does Tinabil 20 work?
Tinabil 20 contains Bilastine, a selective H1 receptor antagonist. It blocks the effects of histamine, a chemical responsible for causing allergic symptoms like itching, swelling, and rashes.
✔️ Side Effects of Tinabil 20
The most common side effects reported include:
- Headache
- Dizziness
- Drowsiness
- Fatigue
These effects occur at a similar rate as placebo in clinical trials.
✔️ Overdose Effects: Tinabil 20
In clinical studies, doses up to 10–11 times the recommended amount (220 mg single dose or 200 mg daily for 7 days) caused mild side effects such as dizziness, headache, and nausea. Serious adverse events or significant QTc prolongation were not observed.
✔️ Dosage & Administration: Tinabil 20
Adults and Adolescents (12 years and older):
- Dose: 20 mg once daily for relief from allergic rhinitis, urticaria, and allergic rhino-conjunctivitis.
- Maximum Dose: 20 mg per day.
- Take the tablet with water on an empty stomach for optimal effectiveness. If a dose is missed, take the next scheduled dose. Avoid doubling the dose.
Children (6–11 years):
- Dose: 10 mg mouth-dissolving tablet once daily.
- The tablet can be placed in the mouth to dissolve quickly or dispersed in a teaspoon of water before swallowing.
- Maximum Dose: 10 mg per day.
Children (2–5 years):
- Dose: 4 ml of suspension once daily.
For all age groups, follow the physician's instructions carefully.
✔️ Interaction
- Drug interactions: Combining Tinabil with ketoconazole, erythromycin, cyclosporine, or diltiazem may increase Tinabil levels, but without significant safety concerns.
- Alcohol: The psychomotor effects of Tinabil 20 mg are similar to alcohol and placebo.
- Lorazepam: Co-administration of Tinabil (20 mg) and lorazepam (3 mg) for 8 days does not enhance CNS depressant effects.
✔️ Contraindications
Do not use Tinabil if you are allergic to Bilastine or any of its components.
✔️ Pregnancy & Lactation
- Limited data are available on the use of Bilastine during pregnancy. Animal studies show no direct harm, but it is best to avoid Bilastine as a precaution during pregnancy.
- It is unknown whether Bilastine passes into breast milk. A healthcare provider should weigh the benefits of breastfeeding against the necessity of the medication for the mother.
✔️ Precautions & Warnings
- Tinabil 20 mg generally does not impair driving ability, but in rare cases, drowsiness may occur.
- Older adults (≥65 years) show similar safety and efficacy as younger patients.
- No dosage adjustment is required for patients with renal or hepatic impairment, as Bilastine is not metabolized in the liver.
- Tinabil should not be used in children under 2 years of age due to insufficient safety data.
✔️ Storage Conditions
- Store below 30°C, away from light and moisture.
- Keep out of reach of children.
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here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
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everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
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