Embardia (Darbepoetin alfa) is indicated for the treatment of anemia due to:
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Avoid consumption of alcohol while taking Embardia SC Injection as it may increase dizziness and sleepiness.
Avoid taking Embardia SC Injection if you are pregnant unless prescribed by a doctor as Embardia SC Injection is a pregnancy category C drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.
Consult your doctor before taking Embardia SC Injection; your doctor will decide whether breastfeeding mothers can take Embardia SC Injection or not
Embardia SC Injection causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns.
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Darbepoetin alfa
Treatment of Anaemia (in cancer and chronic kidney disease)
N increases red blood cell counts by stimulating the bone marrow (soft tissue inside the bones where blood is made) to make more red blood cells.
Embardia 60mcg/0.3ml Injection is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney's specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells).
Darbepoetin alfa is an erythropoiesis-stimulating agent (ESA). It is produced through recombinant DNA technology in Chinese Hamster Ovary (CHO) cells. It stimulates the production of red blood cells by acting on erythroid progenitor cells, similar to erythropoietin. Darbepoetin alfa differs from recombinant human erythropoietin by having five N-linked oligosaccharide chains (compared to three), leading to an extended half-life and prolonged activity.
Chronic Renal Failure (Adult Patients):
Chronic Renal Failure (Pediatric Patients ≥1 year):
Chemotherapy-Induced Anemia (Adult Cancer Patients):
No formal drug interaction studies have been conducted with Darbepoetin alfa.
Store in a cool and dry place away from sunlight
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