Trangina MR (Trimetazidine Dihydrochloride)
Metabolic anti-anginal therapy for better heart energy efficiency
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Trimetazidine Dihydrochloride is a metabolic anti-ischemic agent and the first 3-ketoacyl-CoA thiolase (KAT) inhibitor.
It works by shifting energy production from fatty acid oxidation to glucose oxidation, allowing the heart to produce more energy using the same amount of oxygen.
This enhances cardiac efficiency, reduces lactic acid buildup, and prevents angina attacks, keeping the heart active and oxygen-efficient.
Trangina MR is indicated as an add-on therapy in adults with stable angina pectoris who are inadequately controlled by or intolerant to first-line anti-anginal treatments.
Recommended dose:
35 mg twice daily or 20 mg three times daily, preferably with meals.
Treatment review:
Evaluate after 3 months; discontinue if no improvement is observed.
No significant interactions have been reported.
Safe to use with beta-blockers, calcium channel blockers, nitrates, heparin, lipid-lowering agents, and digitalis preparations.
Store in a cool, dry place, away from light and heat.
Keep out of reach of children.
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