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Clonazepam is used in the treatment of anxiety disorder and Epilepsy/Seizures.
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✅ Description:
Epnil 1mg Tablet contains Clonazepam, a member of the Benzodiazepine group, used for the following purposes:
1. Seizure Disorder (Epilepsy): This medication is prescribed for both adults and children to manage epilepsy, a condition characterized by recurrent seizures or fits, which involve bursts of abnormal electrical activity in the brain. Symptoms may include uncontrolled jerking, shaking, loss of consciousness, or collapsing.
2. Panic Disorder: Epnil 1mg Tablet is also used in adults to treat panic disorder, which is marked by the sudden onset of panic attacks or intense fear, sometimes accompanied by agoraphobia, the fear of open or public spaces.
Safety Advices
Alcohol
UNSAFE
Do not consume alcohol while taking Epnil 1mg Tablet as it may provoke seizures or fits and may worsen side effects possibly leading to severe sedation.
Pregnancy
UNSAFE
Epnil 1mg Tablet is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
Breastfeeding
CONSULT YOUR DOCTOR
Epnil 1mg Tablet is generally not recommended for use in breastfeeding women as it may pass through the breast milk and may cause drowsiness and feeding difficulties. Consult your doctor before taking it.
Driving
CAUTION
Epnil 1mg Tablet may cause drowsiness or sleepiness which can affect your ability to drive and operate machines. Do not drive or operate any machines while taking Epnil 1mg Tablet.
Kidney
CONSULT YOUR DOCTOR
Epnil 1mg Tablet should be used with caution in patients with severe kidney disease. Consult your doctor before taking it.
Liver
CONSULT YOUR DOCTOR
Epnil 1mg Tablet is not recommended for use in patients with severe liver disease. It should be used with caution in patients with mild to moderate liver disease. Consult your doctor before taking it.
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✔️ Uses of Epnil 1mg Tablet
Used to treat
- Seizures disorders
- Panic disorders
✔️ How does Epnil 1mg Tablet work?
Clonazepam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
✔️ Side Effects of Epnil 1mg Tablet
Serious Side Effects:
Be aware of the following serious side effects and contact your doctor immediately if you experience any of them:
- Suicidal Thoughts or Self-Harming
- Unusual Changes in Behavior or Mood
Common Side Effects:
Common side effects of Epnil 1mg Tablet include:
- Drowsiness
- Dizziness
- Impaired Coordination and Balance
- Depression
- Fatigue
- Memory Problems
If any of these symptoms worsen, consult your doctor.
✔️ Quick Suggestions:
- The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
- It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Avoid consuming alcohol as it may increase dizziness and drowsiness.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- Inform your doctor if you experience worsened anxiety, depression anger, or violent behavior and mania while taking this medicine.
- Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremors, and confusion.
✔️ Indication
Epnil 1mg is prescribed for the treatment of seizures, panic attacks, and anxiety disorders. It reduces abnormal nerve cell activity and has a calming effect on the brain.
✔️ Pharmacology:
- Mechanism: Clonazepam, a benzodiazepine, increases GABAergic neurotransmission, reducing nerve cell activity.
- Efficacy: Effective against various seizure types, including absence seizures. Also affects serotonin in animals.
✔️ Dosage & Administration of
- Adults: For seizure disorders, start with a dose of 1.5 mg/day, divided into three doses. Adjust the dosage in 0.5 to 1 mg increments every 3 days, as needed. The maximum daily dose is 20 mg. For panic disorder, begin with 0.25 mg twice a day and increase to 1 mg/day as needed.
- Pediatric Patients: The initial dose for children (up to 10 years or 30 kg body weight) should be 0.01 to 0.03 mg/kg/day, with a maximum of 0.05 mg/kg/day in divided doses.
✔️ Use in Children and the Elderly:
Exercise caution when administering Epnil 1mg Tablet to children and elderly patients, and consult your doctor before use.
✔️ Interaction
- Does not significantly affect the metabolism of phenytoin, carbamazepine, and phenobarbital.
- Interaction with other medications is not well-studied.
✔️ Contraindications:
- Avoid in patients with a severe allergy to benzodiazepines or significant liver infection.
- Exercise caution in open-angle glaucoma, but avoid severe narrow-angle glaucoma.
✔️ Pregnancy & Lactation:
- Risk of congenital malformations; use during pregnancy only if benefits outweigh risks.
- Administer during pregnancy with caution, especially in the last trimester or during labor.
✔️ Precautions & Warnings:
- Epnil 1mg may increase the incidence of generalized tonic-clonic seizures in patients with multiple seizure types.
- Caution When used with valproic acid; it can cause absent status.
✔️ Storage Conditions:
- Store in a cool, dry place, protected from light.
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