Leptic (Clonazepam), a benzodiazepine used for its anticonvulsant, sedative, muscle relaxing, and anxiolytic properties. It is prescribed for treating panic disorder (with or without agoraphobia) and various seizure disorders, including Lennox-Gastaut Syndrome, akinetic seizures, myoclonic seizures, and cases of absence seizures where other medications have failed.
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Avoid consuming alcohol while taking Leptic 2 Tablet. Alcohol can increase the side effects such as dizziness, drowsiness, or sleepiness, making it unsafe.
Leptic 2 Tablet belongs to Pregnancy Category D, which means it is generally not recommended during pregnancy due to potential risks to the fetus. If you are pregnant or planning to become pregnant, consult your doctor before taking this medication. Additionally,
Avoid breastfeeding while on this treatment.
Leptic 2 Tablets may cause side effects like drowsiness, dizziness, or visual disturbances, which could impair your ability to drive or operate machinery safely. If you experience these symptoms, it is important not to engage in such activities.
If you have a history of kidney disorders, Leptic 2 Tablet should be taken cautiously. Your doctor may need to modify the dose to suit your condition.
Use Leptic 2 Tablet with caution if you have a history of liver disease or related conditions. Your doctor may need to adjust your dosage based on your liver health.
It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
Common side effects include CNS depression, drowsiness (50% of cases), and ataxia (30%). Behavioral problems have been observed in 25% of patients. Other side effects include tremors, confusion, depression, hallucinations, and psychosis.
Overdose may cause drowsiness, ataxia, coma, and respiratory depression. Monitoring and supportive treatment are necessary, and flumazenil may be used as an antidote in severe cases.
Clonazepam enhances GABAergic neurotransmission at inhibitory synapses, thereby increasing GABA’s effect on chloride ion flux at postsynaptic receptors. This leads to the anticonvulsant and sedative effects of the drug. It has also shown effects on serotonin and can suppress various types of paroxysmal EEG activity, making it useful in generalized and focal epilepsies.
Oral:
Leptic does not alter the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital. Its effect on the metabolism of other drugs remains unstudied.
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