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Lozicum 1mg Tablet 10pcs
Lorazepam 1mg Tablet
- Manage anxiety
- It is also used as a sedative before any operative dental management or surgery
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✅ Description:
Anxiety is an emotion that is characterized by feelings of tension, worried and intrusive thoughts, and physical changes like increased blood pressure, sweating, trembling, and dizziness. Your doctor might ask you to make some lifestyle changes such as having healthy sleeping and eating habits, managing stress, and meditation.
Lozicum 1 contains Lorazepam which belongs to the group of medicines called Antianxiety agents. It is used to manage anxiety or sleeping difficulties due to anxiety which significantly affects routine life. Lozicum 1 can also be used as a sedative before any operative dental management or surgery.
Lozicum 1 is not recommended for use in patients having lung or liver diseases, myasthenia gravis (very weak or tired muscles), and sleep apnoea (breathing problems while sleeping). It should be used with caution in patients who have kidney diseases, habitual excessive use of drugs or alcohol, personality disorders, depression, history of psychotic illness, history of convulsions, and glaucoma (increased pressure in the eye).
Lozicum 1 should be used with caution in pregnant women. Lozicum 1 is not recommended for use in breastfeeding women. Lozicum 1 should be used with caution in elderly patients. Lozicum 1 should not be used in children below 5 years of age.
Safety Advices
Alcohol
UNSAFE
Consuming alcohol with Lozicum 1 is unsafe.
Pregnancy
UNSAFE
Lozicum 1 is unsafe to use during pregnancy due to definite evidence of risk to the developing baby. However, it may be prescribed in life-threatening situations if the benefits outweigh the risks.
Breastfeeding
UNSAFE
Lozicum 1 is probably unsafe to use during breastfeeding. Limited human data suggest that it may pass into breast milk and harm the baby. Use for short periods and monitor the baby for sleepiness. Gradual withdrawal is recommended.
Driving
UNSAFE
Lozicum 1 may decrease alertness, affect vision, or cause sleepiness and dizziness. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
Use with caution in patients with severe kidney disease. Dose adjustment may be needed. Consult your doctor.
Liver
CONSULT YOUR DOCTOR
Use with caution in patients with severe liver disease. Dose adjustment may be needed. Use is not recommended in patients with severe liver disease.
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✔️ Uses of Lozicum 1
- Manage anxiety
✔️ How does Lozicum 1 work?
Lozicum 1 is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA), which suppresses the abnormal and excessive activity of nerve cells in the brain.
✔️ Side Effects of Lozicum 1
- Sedation
- Drowsiness
- Ataxia
- Dizziness
- Confusion
- Depression
- Hypotension
- Fatigue
- Muscle weakness
- Amnesia or memory impairment
✔️ Quick Suggestions:
- This medicine has a high potential for habit-forming. Take it only as per the dose and duration advised by your doctor.
- It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how this medicine affects you.
- Avoid consuming alcohol as it may increase dizziness and drowsiness.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- Do not stop taking medication suddenly without consulting your doctor.
✔️ Indication of Lozicum 1
- Anxiety
- Status epilepticus
- Sedation
- Psychosomatic, organic, or psychotic illness
- Insomnia associated with anxiety
- Nervousness
- Restlessness
- Nausea and vomiting related to chemotherapy and anticonvulsants
- As a premedical before dental or general surgery or before investigative procedures
✔️ Pharmacology
Lorazepam is a short-acting tranquilizer of the benzodiazepine group. It is an agonist at benzodiazepine receptors in the CNS. It exerts a depressant action on the CNS, which may be mediated by potentiating the inhibitory actions of GABA (gamma amino butyric acid) in the CNS. This will result in a diminution of the ascending activating systems, particularly the serotonergic and noradrenergic pathways from the brain stem or the mid-brain to the cerebral cortex.
✔️ Dosage & Administration of Lorazepam 1
Adult Dose:
- Anxiety Disorders: 1-6 mg/day in 2 or 3 divided doses, up to 10 mg/day.
- Insomnia Associated with Anxiety: 1-4 mg/day at bedtime.
- Premedication in Surgery: 2-3 mg the night before the operation, then a smaller dose in the morning if needed.
Child Dose:
- Status Epilepticus: 0.05-0.1 mg/kg IV over 2-5 minutes; not to exceed 4 mg/dose; may repeat every 10-15 minutes as needed.
✔️ Interaction
- Additive CNS effects with barbiturates, phenothiazines, antidepressants, and MAOIs.
- Increased sedation with scopolamine.
- Reduced effect with caffeine, theophylline, or aminophylline.
- Increased plasma levels with sodium valproate or probenecid.
✔️ Contraindications
- Severe hepatic impairment
- Respiratory depression
- Acute narrow-angle glaucoma
- Pregnancy and lactation
✔️ Pregnancy & Lactation
Safety of Lorazepam in pregnancy has not been established. Because the use of this drug is rarely a matter of urgency, the use of Lorazepam during this period should almost always be avoided.
It is not known whether oral Lorazepam is excreted in human milk like other benzodiazepine tranquilizers. As a general rule, nursing should not be undertaken while a patient is on a drug since many drugs are excreted in human milk.
✔️ Precautions & Warnings
- Use with caution in patients with compromised pulmonary function, myasthenia gravis, cardiovascular or cerebrovascular disease, impaired gag reflex, or those at risk of falls.
- Avoid abrupt withdrawal.
- Monitor respiratory and cardiovascular status, BP, heart rate, symptoms of anxiety, CBC, and liver function tests.
✔️ Storage Conditions:
Store between 20-25°C
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here information is for informational purposes only.
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lab tests, medicines, all possible side effects, drug interactions,
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