Lozicum 1mg Tablet 10pcs

Uses of Lozicum 1

• Manage anxiety

How does Lozicum 1 work?

Lozicum 1 is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA), which suppresses the abnormal and excessive activity of nerve cells in the brain.

Side Effects of Lozicum 1

• Sedation
• Drowsiness
• Ataxia
• Dizziness
• Confusion
• Depression
• Hypotension
• Fatigue
• Muscle weakness
• Amnesia or memory impairment

Quick Suggestions:

• This medicine has a high potential for habit-forming. Take it only as per the dose and duration advised by your doctor.
• It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how this medicine affects you.
• Avoid consuming alcohol as it may increase dizziness and drowsiness.
• Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
• Do not stop taking medication suddenly without consulting your doctor.

Indication of Lozicum 1

• Anxiety
• Status epilepticus
• Sedation
• Psychosomatic, organic, or psychotic illness
• Insomnia associated with anxiety
• Nervousness
• Restlessness
• Nausea and vomiting related to chemotherapy and anticonvulsants
• As a premedical before dental or general surgery or before investigative procedures

Pharmacology

Lorazepam is a short-acting tranquilizer of the benzodiazepine group. It is an agonist at benzodiazepine receptors in the CNS. It exerts a depressant action on the CNS, which may be mediated by potentiating the inhibitory actions of GABA (gamma amino butyric acid) in the CNS. This will result in a diminution of the ascending activating systems, particularly the serotonergic and noradrenergic pathways from the brain stem or the mid-brain to the cerebral cortex.

Dosage & Administration of Lorazepam 1

Adult Dose:

• Anxiety Disorders: 1-6 mg/day in 2 or 3 divided doses, up to 10 mg/day.
• Insomnia Associated with Anxiety: 1-4 mg/day at bedtime.
• Premedication in Surgery: 2-3 mg the night before the operation, then a smaller dose in the morning if needed.

Child Dose:

• Status Epilepticus: 0.05-0.1 mg/kg IV over 2-5 minutes; not to exceed 4 mg/dose; may repeat every 10-15 minutes as needed.

Interaction

• Additive CNS effects with barbiturates, phenothiazines, antidepressants, and MAOIs.
• Increased sedation with scopolamine.
• Reduced effect with caffeine, theophylline, or aminophylline.
• Increased plasma levels with sodium valproate or probenecid.

Contraindications

• Severe hepatic impairment
• Respiratory depression
• Acute narrow-angle glaucoma
• Pregnancy and lactation

Pregnancy & Lactation

Safety of Lorazepam in pregnancy has not been established. Because the use of this drug is rarely a matter of urgency, the use of Lorazepam during this period should almost always be avoided.

It is not known whether oral Lorazepam is excreted in human milk like other benzodiazepine tranquilizers. As a general rule, nursing should not be undertaken while a patient is on a drug since many drugs are excreted in human milk.

Precautions & Warnings

• Use with caution in patients with compromised pulmonary function, myasthenia gravis, cardiovascular or cerebrovascular disease, impaired gag reflex, or those at risk of falls.
• Avoid abrupt withdrawal.
• Monitor respiratory and cardiovascular status, BP, heart rate, symptoms of anxiety, CBC, and liver function tests.

Storage Conditions:

Store between 20-25°C

2. Can I develop tolerance to Lozicum 1?

Answer: Yes, there is a possibility of developing tolerance to Lozicum 1 as it belongs to the benzodiazepine class of medicines. Over time, the beneficial effects may become less apparent. If you feel that the medication is becoming less effective, consult with your doctor.

3. Is Lozicum 1 a habit-forming drug?

Answer: Yes, ATIVAN 2MG TABLET has the potential to be habit-forming, especially if taken in higher doses or for extended periods. The risk of dependence is higher in individuals with a history of drug or alcohol abuse or personality disorders. Always inform your doctor if you have any such history before starting the medication.

4. Can I stop taking Lozicum 1 if I start to feel better?

Answer: No, you should not stop taking ATIVAN 2MG TABLET abruptly. It should be gradually tapered off under your doctor's supervision to avoid withdrawal symptoms such as headaches, muscle pain, dizziness, nausea, and anxiety. Consult your doctor before making any changes to your dosage.

5. Does Lozicum 1 affect my ability to drive?

Answer: Yes, Lozicum 1 can make you sleepy or affect your concentration, particularly if you have not had enough sleep. Do not drive or operate machinery if you feel sleepy or have impaired concentration after taking the medication. Resume these activities only when you feel normal again.

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