Tofacent 5mg Tablet | Tofacitinib | Antirheumatics | 10pcs
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Tofacent 5mg Tablet 10pcs

Generic: Tofacitinib

Type: Tablet

Pack Size: 10 Pcs

Tofacent 5 treats inflammatory conditions such as:

  • Rheumatoid arthritis
  • Psoriatic arthritis
  • Ulcerative colitis
  • Ankylosing spondylitis
  • Polyarticular juvenile idiopathic arthritis
  • Juvenile psoriatic arthritis

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Discount Price: ৳ 332.5
MRP: ৳ 350 5% Off

⪼ Save  ৳: 17.5  in this Product


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✅ Description:

Tofacent 5mg Tablet

  • Used to treat inflammatory diseases such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis.
  • Also used to treat polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis in children.
  • Can be used alone or in combination with other drugs, such as methotrexate.
  • Not recommended for use in patients with severe liver diseases, bloodstream infections, or active tuberculosis.
  • Should be used with caution in patients with various conditions, including infections, chronic lung disease, tuberculosis, hepatitis B or C, liver, kidney, or heart diseases, cancer, skin cancer risk, smoking habits, lactose intolerance, inflammation of the large intestine, stomach or intestine ulcers, blood pressure, high cholesterol, at risk of developing a blood clot, planning to get vaccinated, or have undergone major surgery.
  • Not to be used by pregnant or breastfeeding women.
  • Caution in patients over the age of 65.
  • Safety and effectiveness in children under the age of two are not yet established.

Safety Advices


Alcohol
UNSAFE

Interaction with alcohol is unknown. 


Pregnancy
CONSULT YOUR DOCTOR

Tofacent 5mg Tablet is not recommended for use in pregnant women or women planning to have a baby. If you are a woman of childbearing age, you should use effective birth control during treatment and for at least 4 weeks after the last dose. Consult your doctor before taking it.


Breastfeeding
CONSULT YOUR DOCTOR

Tofacent 5mg Tablet is not recommended for use in breastfeeding women. Consult your doctor before taking it.


Driving
SAFE

Tofacent 5mg Tablet does not affect your ability to drive or use machines.


Kidney
CAUTION

Tofacent 5mg Tablet should be taken with caution in patients with kidney disease. The dose will be adjusted by your doctor Consult your doctor before taking it.


Liver
CAUTION

Tofacent 5mg Tablet is not recommended in patients with severe liver problems such as cirrhosis (scarring of the liver). It should be used with caution in patients having other liver diseases such as hepatitis B or hepatitis C. Dose will be adjusted by your doctor. Consult your doctor before taking it.

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✔️ Uses of Tofacent 5mg Tablet

Tofacitinib is used in the treatment of rheumatoid arthritis.

✔️ How does Tofacent 5mg Tablet work?

Tofacent 5mg Tablet works by blocking the action of the enzyme, Janus kinase. This decreases inflammation and joint damage in rheumatoid arthritis.

✔️ Side Effects of Tofacent 5mg Tablet
  • The most common adverse reactions include upper respiratory tract infection, nasopharyngitis, diarrhea, and headache.
  • Reported in ≥5% of patients treated with Tofacitinib for ulcerative colitis: nasopharyngitis, elevated cholesterol levels, headache, upper respiratory tract infection, increased blood creatine phosphokinase, rash, diarrhea, and herpes zoster.
✔️ Quick Suggestions:
  • Used alone or in combination with other medicines for the treatment of rheumatoid arthritis that did not improve with other anti-rheumatic drugs.
  • It may take 3 to 6 months to feel the maximum effect of this medication.
  • Regular blood tests may be conducted to monitor liver function, kidney function, blood counts, or cholesterol levels.
  • Tofacitinib can make it a bit harder for people to fight off infections.
  • Inform your doctor if you have symptoms of an infection such as fever, chills, cough, and muscle aches.
  • A TB (tuberculosis) skin test and a chest X-ray may be done before starting treatment with this medication.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
✔️ Indications of Tofacent 5mg Tablet

Tofacitinib 

  • For adult patients with moderately to severely active rheumatoid arthritis who have had an insufficient response or intolerance to methotrexate.
  • Can be used alone or in combination with other nonbiologic disease-modifying antirheumatic medicines like methotrexate.
  • Also indicated for adult patients with active psoriatic arthritis who have had an unsatisfactory response or sensitivity to methotrexate or other disease-modifying antirheumatic medications.
  • Used to treat ulcerative colitis in adults with moderately to highly active ulcerative colitis (UC).
✔️ Pharmacology
  • Tofacitinib is a Janus kinase (JAK) inhibitor that prevents the body from responding to cytokine signals.
  • Suppresses the phosphorylation and activation of STATs by inhibiting JAKs.
  • Blocks the JAK-STAT pathway, reducing the inflammatory response.
✔️ Dosage & Administration of Tofacent 5mg Tablet
  • Rheumatoid Arthritis: Tofacitinib 5 mg twice daily or Tofacitinib 11 mg once daily. Recommended dosage in patients with moderate and severe renal impairment or moderate hepatic impairment is Tofacitinib 5 mg once daily.
  • Psoriatic Arthritis: Tofacitinib 5 mg twice daily or Tofacitinib 11 mg once daily. Recommended dosage in patients with moderate and severe renal impairment or moderate hepatic impairment is Tofacitinib 5 mg once daily.
  • Ulcerative Colitis: Tofacitinib 10 mg twice daily for at least 8 weeks; then 5 or 10 mg twice daily. Discontinue after 16 weeks of 10 mg twice daily if adequate therapeutic benefit is not achieved. Use the lowest effective dose to maintain response.
✔️ Interaction
  • Inhibitors: Cytochrome P450 3A4 (CYP3A4) inhibitors of high potency (e.g., Ketoconazole) may require adjustment of Tofacitinib dosage.
  • Inducers: Inducers of CYP (e.g., Rifampin) may result in a lower clinical response to Tofacitinib.
✔️ Contraindications

Hypersensitivity to the active substance or to any of the excipients.

✔️ Pregnancy & Lactation
  • Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.
  • Not known whether Tofacitinib is excreted in human milk. Caution is advised during lactation.
✔️ Precautions & Warnings
  • Caution during active serious infections, including localized infections.
  • Increased risk of gastrointestinal perforations.
  • Regular laboratory monitoring is recommended for potential changes in lymphocytes, neutrophils, hemoglobin, liver enzymes, and lipids.
  • Avoid live vaccines while using Tofacitinib.
✔️ Storage Conditions

Store below 30°C. Protect from light & moisture. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

Tofacent 5mg Tablet should be used with caution in patients aged 65 and older due to an increased risk of infections, heart attacks, and certain cancers. Consult your doctor before taking it.

If you forget a dose, do not take a double dose. Continue as usual until the next scheduled dose and meal. Consult your doctor for advice.

Regular monitoring of blood cell levels, cholesterol, and liver/kidney functions is advised while taking Tofacent 5mg Tablet.

Tofacent 5mg Tablet is not recommended for use by pregnant or breastfeeding women. Effective birth control is required during treatment.

Tofacent 5mg Tablet is used in children over 2 years of age for specific conditions. Consult your doctor before giving it to your child.

No, you should not take tocilizumab along with Tofacitinib. Taking both medicines together can further increase the risk of infection and may lead to complications.

Tofacitinib affects the immune system, reducing the ability to fight infections. Serious infections, including tuberculosis, may occur. It is advised to treat these infections in a hospital.

Tofacent 5mg Tablet contains tofacitinib, used for inflammatory diseases like rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis. It is also used in children for juvenile idiopathic arthritis and juvenile psoriatic arthritis.

Inform your doctor if you have liver problems before starting Tofacitinib. It may cause an increase in liver enzymes, and your liver function needs to be investigated. It can be given to patients with mild to moderate liver function impairment but should not be prescribed to those with severe liver impairment.

Tofacitinib usually takes about 2 to 8 weeks to start feeling better, and it can take 3 to 6 months to feel the maximum effect.

Blood tests may be needed to check red blood cell count, white blood cell count, cholesterol levels, and liver enzymes. Tuberculosis testing may also be advised before starting Tofacitinib.

Tofacitinib may increase the risk of certain cancers (lymphoma and skin cancers) by affecting the immune system. Inform your doctor if you ever had or have any type of cancer.
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Check our pricing section for Tofacent 5mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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