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Bilexa 100 Inhalation Capsule
Vilanterol Trifenatate + Fluticasone Furoate is used in the treatment of allergic conditions, chronic obstructive pulmonary disease, and asthma.
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✅ Description:
Bilexa 100 Inhalation is a combination medication classified as a respiratory stimulant, commonly prescribed for treating asthma and chronic obstructive pulmonary disease (COPD).
- Asthma is a chronic respiratory condition characterized by narrowed and inflamed airways, causing difficulty in breathing. Symptoms include shortness of breath and wheezing.
- COPD is a group of progressive lung diseases, including emphysema (shortness of breath) and chronic bronchitis (bronchial inflammation), leading to restricted airways.
This medication contains:
- Fluticasone Furoate: An inhaled corticosteroid that reduces inflammation by blocking certain chemicals that trigger inflammatory responses. This helps relieve symptoms such as sneezing, shortness of breath, and wheezing.
- Vilanterol: A long-acting beta-agonist (LABA) that belongs to the bronchodilator class. It works by relaxing airway muscles, helping to open the lungs for easier breathing.
- Avoid if allergic to any component of this medication.
- Not recommended for those with life-threatening asthma or COPD conditions.
- Inform your doctor if you have any lung infections, glaucoma, cataracts, osteoporosis, tuberculosis, kidney/liver problems, or if you are on immunosuppressant therapy.
- Consult your doctor if you are pregnant or breastfeeding.
- Not recommended for children under 12 years.
Your doctor will set the appropriate dose and duration based on your condition. Use as directed by your doctor. If you experience severe breathing difficulties or wheezing while using this medication, contact your doctor immediately for an alternative treatment.
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✔️ Indications: Bilexa 100 Inhalation Capsule
- COPD: Long-term, once-daily maintenance treatment for airflow obstruction and to reduce exacerbations.
- Asthma: Once-daily treatment for patients aged 18 years and older.
- Important Limitation: Not for relief of acute bronchospasm.
✔️ Composition: Bilexa 100
- 25/100 Capsule: Contains Vilanterol 25 mcg (as Vilanterol Trifenatate INN) and Fluticasone Furoate INN 100 mcg.
- 25/200 Capsule: Contains Vilanterol 25 mcg and Fluticasone Furoate 200 mcg.
✔️ Pharmacology:
- Vilanterol Trifenatate: A selective, long-acting beta-2 agonist (LABA) that relaxes bronchial smooth muscle by increasing intracellular cyclic AMP, inhibiting hypersensitivity mediator release.
- Fluticasone Furoate: A corticosteroid with anti-inflammatory activity, acting on multiple inflammatory cells and mediators to manage COPD and asthma.
✔️ Most side effects are mild and may subside with time. Common ones include:
- Sore throat, sneezing, headache
- Cough, low fever, chest tightness
- Stuffy nose, mouth fungal infection
- Nausea, stomach upset, dizziness, nervousness, vomiting
If these side effects persist or worsen, consult your doctor.
✔️ Dosage & Administration: Bilexa 100
- Route: Oral inhalation only (do not swallow).
- Device Use: Insert capsule into inhaler only when ready to use. Rinse mouth post-inhalation to prevent oropharyngeal candidiasis.
- Dosage:
- COPD: 1 inhalation of 25/100 mcg once daily.
- Asthma: 1 inhalation of 25/100 mcg or 25/200 mcg once daily.
- Children & Adolescents: Not indicated for those under 18 years.
- Hepatic Impairment: Monitor for systemic corticosteroid effects due to increased fluticasone exposure in moderate to severe cases.
Clinical trial data on overdose is unavailable; consult medical support if an overdose occurs.
✔️ Interaction
- CYP3A4 Inhibitors (e.g., ketoconazole): May cause systemic corticosteroid and cardiovascular effects.
- MAO Inhibitors and Tricyclic Antidepressants: May enhance cardiovascular effects.
- Beta-blockers: Risk of bronchospasm due to interference with bronchodilation.
- Diuretics: Monitor for hypokalemia and ECG changes, especially with non–potassium-sparing diuretics.
✔️ Contraindications:
- Primary Treatment for Acute Episodes: Not suitable for acute COPD or asthma treatment.
- Hypersensitivity: Contraindicated in severe milk protein allergies or hypersensitivity to any components.
✔️ Precautions & Warnings
- Risk with LABA Monotherapy: Increases risk of severe asthma-related events.
- Not for Acute Symptom Relief: Avoid acutely worsening COPD or asthma.
- Oral Thrush (Candidiasis): Periodic monitoring is recommended; rinse mouth post-use.
- Pneumonia Risk in COPD Patients: Monitor for symptoms.
- Infections: Use with caution if there is an existing infection or a history of tuberculosis or ocular herpes.
- Adrenal Suppression: Taper systemic corticosteroids gradually when transitioning to this treatment.
- Eye Health: Long-term use may increase glaucoma and cataract risk.
- Use with Caution in Certain Conditions: Includes cardiovascular disorders, thyrotoxicosis, diabetes, and convulsive disorders. Keep out of the reach of children.
✔️ Storage Conditions
Keep below 30°C temperature, away from light & moisture.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
