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Indications
Salbutamol is indicated as a bronchodilator for use in-
Pharmacology
Salbutamol is a synthetic sympathomimetic agent with a high affinity for beta-2 adrenergic receptors. Salbutamol causes bronchodilation by stimulating beta-2-adrenergic receptors in bronchial smooth muscles, causing bronchial muscle fibers to relax. Spirometric measurements show an improvement in pulmonary function as a result of this action.
Dosage & Administration
Salbutamol tablet or syrup-
Children:
Adults:
Interaction
Some patients receiving Co-amoxiclav experienced bleeding and prothrombin time prolongation. Co-amoxiclav, like other broad-spectrum antibiotics, may reduce the efficacy of oral contraceptives, and patients should be warned about this. Concurrent use of allopurinol and amoxicillin may increase the likelihood of allergic skin reactions. There is no information on the use of Co-amoxiclav and
Contraindications
Hypersensitivity to penicillin has a long history. Cross-sensitivity with other beta-lactam antibiotics, such as cephalosporins, should be considered. Patients with a history of Co-amoxiclav or Penicillin-associated cholestatic jaundice should avoid this medication.
Side Effects
Salbutamol may cause fine tremors of skeletal muscles (particularly the hands), palpitations, and muscle cramps. Tachycardia, tenseness, headaches, and peripheral vasodilatation have been reported after large doses.
Pregnancy & Lactation
Only if the possible benefit outweighs the risk to the fetus should the medicine be used during pregnancy. This medication is not known to be excreted in human milk. Because of the possibility for tumorigenicity revealed in some animal studies for Salbutamol, a decision should be made whether to stop breastfeeding or stop taking the medicine, taking into account the drug's relevance to the mother.
Precautions & Warnings
Salbutamol should be used with caution in patients with hyperthyroidism, cardiovascular disease, occlusive vascular disorders, hypertension, and aneurysms. Hypokalaemia associated with high doses of Salbutamol may result in increased susceptibility to digitalis-induced cardiac arrhythmia. Tachyphylaxis with resistance may occur with prolonged use of high dosage. Care is necessary when treating patients with diabetes mellitus or closed-angle glaucoma, and in those receiving antihypertensive therapy
Storage Conditions
Do not store at temperatures above 30°C. Keep out of children's reach.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.