Brodil Levo Syrup

✔️ Uses of Brodil Levo Syrup

Brodil Levo Syrup can treat the below-provided problems:

• Asthma
• Bronchospasm
• Chronic Obstructive Pulmonary Disorder (Copd)

✔️ How does Brodil Levo Syrup work?

This medicine works by relaxing and opening the blocked air passages leading to the lungs. It improves the amount of airflow to the lungs and makes breathing easier.

✔️ Side Effects of Brodil Levo Syrup

Major & minor side effects of Brodil Levo Syrup 

• Headache
• Blocked or runny nose
• Shaking and trembling of arms and feet
• Decreased appetite
• Muscle pain and cramps
• Anxiety and nervousness
• Swelling of eyelids, face, lips, tongue
• Nausea
• Skin rash
• Chest pain and discomfort
• Sleep disturbances
• Increased heartbeat
• Difficulty in swallowing
• Difficulty in speaking
• Dizziness and fainting
• Chest tightness

✔️ Quick Suggestions:

• Healthy Diet and Exercise: Eating a nutritious diet and engaging in regular exercise can strengthen your breathing muscles and support your immune system.
• Foods to Avoid: Certain foods like cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice have been associated with potentially worsening asthma symptoms in some individuals. It may be helpful to monitor your own response to these foods and make adjustments as needed.
• Stress Management Techniques: Practices like meditation, deep breathing exercises, regular exercise, and progressive muscle relaxation techniques can help reduce stress, which in turn may lower the risk of an asthma attack.
• Quit Smoking: Smoking is harmful to respiratory health and can worsen breathing problems. It's advisable to quit smoking to improve your overall lung function and allow medications like  Brodil Levo Syrup to work more effectively.
• Breathing Exercises: Learning and practicing specific breathing exercises can aid in maximizing lung capacity and improving respiratory function.
• In addition to these lifestyle recommendations, you also mentioned some specific precautions to consider:
• Monitoring Blood Glucose Levels: Bronchodilators, including  Brodil Levo Syrup, can sometimes elevate blood sugar levels. If you have diabetes, it's important to monitor your blood glucose levels regularly.
• Checking Heart Condition: If you have a pre-existing heart condition, it may be beneficial to monitor your heart health with an electrocardiogram (ECG) if you experience any rapid heartbeat or changes in blood pressure while using Brodil Levo Syrup.
• Blood Examination for Potassium Levels: Hypokalemia, or low blood potassium levels, can potentially occur with certain medications. If your doctor deems it necessary, a blood examination can help rule out this possibility.

✔️ Indication

Brodil Levo Syrup is used to treat respiratory conditions like chronic obstructive pulmonary disease (COPD) and asthma characterized by difficulty in breathing, coughing, and whistling sound while breathing.

✔️ Pharmacology

Levosalbutamol is a specific beta-2 agonist that contains only the active (R)-enantiomer of salbutamol. This distinguishes it from racemic salbutamol, which consists of both (R)-salbutamol and (S)-salbutamol enantiomers. The presence of (S)-salbutamol in racemic salbutamol can contribute to beta-mediated adverse effects.

The primary mechanism of action of Levosalbutamol is unimpeded by (S)-salbutamol. It acts as a bronchodilator by stimulating the beta-2 adrenergic receptors present in bronchial smooth muscles. This stimulation leads to relaxation of the muscle fibers in the bronchial tubes, resulting in bronchodilation.

Comparatively, Levosalbutamol can achieve clinically comparable bronchodilation to racemic salbutamol at lower doses. This reduced dose requirement can help minimize the beta-mediated side effects associated with higher doses of racemic salbutamol.

✔️ Dosage & Administration of

Dosage:

Syrup-

Adults: 5-10 ml three times daily.

Children: (6-11 years): 5 ml three times daily.

Administration:

• Take the medicine as instructed by the doctor.
• Shake well before use.
• Use a cup, spoon, or dropper for the exact quantity.
• Do not consume it directly from the bottle.

✔️ Interaction

Interactions with Other Medications:

• Decreased Effect: Beta-blockers, particularly nonselective agents, can block the effects of levalbuterol. Additionally, digoxin levels may be decreased when taken concomitantly with Brodil Levo Syrup.
• Increased Effect/Toxicity: Brodil Levo Syrup may enhance the effects of medications that deplete potassium, such as loop or thiazide diuretics. The cardiac effects of the syrup may be potentiated in patients receiving MAOIs, tricyclic antidepressants, sympathomimetics (e.g., amphetamine, dobutamine), or inhaled anesthetics (e.g., enflurane).
• Regarding the specific drug interactions with digoxin and epinephrine, it's important to discuss these potential interactions with your healthcare provider for personalized advice.

Interactions with Diseases:

• Paradoxical Bronchospasm: Brodil Levo Syrup, like other bronchodilators, may rarely provoke paradoxical bronchospasm (bronchospasm that worsens instead of improves).
• Hypersensitivity Reactions: Immediate hypersensitivity reactions, including angioedema, oropharyngeal edema, urticaria, rash, and anaphylaxis, have been reported. If such reactions occur, immediate medical attention is required.
• Cardiovascular Disease: Use Brodil Levo Syrup with caution in patients with cardiovascular diseases, including coronary artery disease, hypertension, and a history of arrhythmias, as it may increase heart rate, blood pressure, or other cardiac symptoms, including EKG changes.
• Excessive Use: Avoid using Brodil Levo Syrup in doses higher than recommended, as excessive use of sympathomimetics has been associated with fatalities.
• Additional Anti-inflammatory Medication: If the need for bronchodilators becomes more frequent, it is important to evaluate the need for additional anti-inflammatory medication, such as corticosteroids, to control asthma.
• Diabetes and Hypokalemia: Use Brodil Levo Syrup with caution in diabetic patients and those with hypokalemia (low blood potassium levels).

Labor and Delivery: Caution should be exercised when using Brodil Levo Syrup during labor and delivery.

Furthermore, avoiding or limiting alcohol intake is recommended due to the potential for worsened side effects like sleepiness and shakiness.

✔️ Contraindications

Patients having a history of hypersensitivity to Levosalbutamol or any of its components should avoid taking it.

✔️ Pregnancy & Lactation

Pregnancy: It is important to consider the potential risks and benefits before using any medication during pregnancy. While Levosalbutamol is generally considered safe for use during pregnancy when the potential benefit outweighs the risk to the fetus, it is always best to consult with a healthcare provider who can evaluate your specific situation and provide personalized advice.

Breastfeeding: Levosalbutamol is not known to be eliminated in human milk. However, caution should still be exercised when administering oral Levosalbutamol to a nursing woman. It is advisable to consult with a healthcare provider to assess the potential risks and benefits of using this medication while breastfeeding.

✔️ Precautions & Warnings

Medical Conditions: It is essential to inform your doctor if you have any heart, liver, or kidney diseases, hyperthyroidism (overactive thyroid), hypokalaemia (low blood potassium levels), stomach ulcer, seizures (fits), high blood pressure, or diabetes before taking Regarding the specific drug interactions with digoxin and epinephrine, it's important to discuss these potential interactions with your healthcare provider for personalized advice.

Hypokalaemia: Bronchodilators, including Regarding the specific drug interactions with digoxin and epinephrine, it's important to discuss these potential interactions with your healthcare provider for personalized advice., may cause hypokalaemia in some patients, which can lead to severe heart problems. It is important to use the syrup cautiously and inform your doctor if you have any history or risk factors for hypokalaemia.

Blood Glucose Levels: Regarding the specific drug interactions with digoxin and epinephrine, it's important to discuss these potential interactions with your healthcare provider for personalized advice. may cause a rise in blood glucose levels. If you have diabetes, it is recommended to monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted if needed.

Pregnancy and Lactation: Inform your doctor if you plan to conceive, are already pregnant, or are a lactating mother before starting  Brodil Levo Syrup. Your doctor can assess the potential risks and benefits and provide appropriate guidance.

Driving and Operating Machinery:  Brodil Levo Syrup may cause dizziness and drowsiness. It is advisable to avoid driving or operating machinery if you experience these side effects, as they can affect your ability to perform such tasks safely.

Alcohol Consumption: It is recommended to avoid drinking alcohol while being treated with  Levo Syrup, as it can worsen sleepiness and affect mental ability.

Children: Brodil Levo Syrup is not recommended for children below six years of age.

✔️ Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.