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Catium Trio 80 Convicap 1 Strip
Catium Trio is a triple-combination inhalation therapy containing:
✔ Indacaterol Acetate – an ultra-LABA (long-acting beta-2 agonist) that works as a bronchodilator to relax airway muscles and improve breathing.
✔ Glycopyrronium Bromide – an ultra-LAMA (long-acting muscarinic antagonist) that helps prevent bronchoconstriction by blocking acetylcholine receptors.
✔ Mometasone Furoate – a high-affinity corticosteroid with potent anti-inflammatory properties to reduce airway inflammation and hypersensitivity.
This combination helps enhance lung function, reduce asthma symptoms, and prevent exacerbations, improving overall respiratory health for patients with chronic asthma.
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✅ Description:
Catium Trio is a specialized inhalation powder medication designed for the maintenance treatment of asthma and to help prevent asthma exacerbations in adult patients. It is specifically recommended for individuals who are not adequately controlled with a combination therapy of a long-acting beta-2 agonist (LABA) and an inhaled corticosteroid (ICS).
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✔️ Pharmacology – How Catium Trio Works?
💨 Indacaterol (Ultra-LABA)
- A long-acting beta-2 adrenergic receptor agonist that promotes bronchodilation by increasing intracellular cyclic AMP (cAMP) levels.
- Rapid onset of action and long-lasting effects ensure sustained airway relaxation.
- While primarily targeting beta-2 receptors in the lungs, it also has minimal interaction with beta-1 and beta-3 receptors, reducing cardiovascular side effects.
💨 Glycopyrronium (Ultra-LAMA)
- A muscarinic receptor antagonist that blocks bronchoconstriction by preventing acetylcholine from acting on airway smooth muscles.
- Highly selective for M1 and M3 receptors, ensuring effective airway relaxation with minimal M2 receptor interaction.
- Rapid absorption and long duration allow for once-daily dosing.
💨 Mometasone Furoate (ICS - Inhaled Corticosteroid)
- A potent glucocorticoid receptor agonist with strong anti-inflammatory effects.
- Suppresses pro-inflammatory cytokines, including IL-1, IL-5, IL-6, and TNF-alpha, which contribute to airway inflammation.
- Reduces the release of leukotrienes, helping to control asthma-related allergic responses.
✔️ Why Choose Catium Trio for Asthma Management?
✅ Triple-action therapy: Relieves airway constriction, reduces inflammation and prevents asthma flare-ups.
✅ Once-daily dosing: Ensures convenient and effective long-term control.
✅ Clinically tested ingredients: Backed by research for improved lung function and symptom relief.
✔️ Dosage & Administration
✔ For inhalation use only with the prescribed inhalation device.
✔ One capsule per day – do not exceed the recommended dose.
✔ Remove the capsule just before use and inhale the full dose through the inhaler.
✔ Not intended for oral ingestion.
✔️ Use with caution in patients taking:
- Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants – may prolong the QT interval.
- Methylxanthine derivatives, steroids, or non-potassium-sparing diuretics – may increase the risk of hypokalemia.
- Beta-blockers (ß2-adrenergic blockers) – should not be used together with Catium Trio, as they may counteract its therapeutic effects.
✔️ Potential Side Effects
🔹 Most common adverse reactions reported over 52 weeks of use include:
✔ Nasopharyngitis (common cold symptoms)
✔ Upper respiratory tract infections
✔ Headaches
✔️ Contraindications
❌ Do not use Catium Trio if you have a known hypersensitivity to any of its active ingredients or excipients.
✔️ Use in Pregnancy & Lactation
🤰 Pregnancy: Limited data is available. Animal studies suggest potential fetal risk, so use only if the benefits outweigh potential harm.
🤱 Breastfeeding: The presence of the drug in human milk is unknown, but similar corticosteroids have been found in breast milk. Use with caution under medical advice.
✔️ Precautions & Warnings
✔ Not for acute asthma attacks – This is a maintenance therapy, not a rescue inhaler.
✔ Monitor cardiovascular effects – It may increase heart rate or blood pressure in some patients.
✔ Diabetes caution – May cause elevated blood sugar levels, requiring closer plasma glucose monitoring.
✔ Oral hygiene recommendation – Rinse your mouth with water (without swallowing) or brush your teeth after inhalation to prevent oral fungal infections (oropharyngeal candidiasis).
✔ Proper usage – Do not swallow capsules; they should only be used with the inhaler device.
✔️ Storage Instructions
✔ Store below 30°C, away from light and moisture.
✔ Keep out of reach of children.
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The information contained herein should NOT be used as a substitute
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