Contine 200mg
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Contine 200mg 10Pcs

Generic: Theophylline

Type: Tablet

Pack Size: 10 Pcs

Tablet Manufacturer/Distributor: Aristopharma Limited Generic Name: Theophylline 200 mg Tablet


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Discount Price: ৳ 14.93
MRP: ৳ 16.05 7% Off

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✅ Description:

Indications of Contine 200

Contine is indicated for the prevention & treatment of symptoms of asthma and reversible bronchospasm associated with and emphysema.

Pharmacology

Contine (Theophylline) is a bronchodilator, structurally classified as a xanthine derivative. lt has two distinct actions in the airways causes pulmonary reversible obstruction; smooth muscle relaxation and suppression of the response of the airways to stimuli. lt also causes pulmonary vasodilation, stimulates mucociliary clearance and inhibits mast cell mediator release. Theophylline force of contraction increases the of diaphragmatic muscles.

 

Dosage & Administration

The dose of theophylline must be individualized on the basis of peak serum theophylline concentration measurements in order to achieve a dose that will provide maximum potential benefit with minimal risk of adverse effects. Most of the sustained release preparations may be administered every 12 hours in adults while administration every 8 hours may be necessary in some children with markedly rapid hepatic metabolism of theophylline. The recommended maintenance dose within accepted therapeutic range is as follows:

1-6 months: 10 mg/Kg/day.

6 months-1 year: 12-18 mg/Kg/day

1 year-8 years: 24-24 mg/Kg/day

9-11 years: 16 mg/Kg/day

12 years-15 years: 13 mg/Kg/day

16 years or older: 10 mg/Kg/day (Do not exceed 900 mg/day)

 

Interactions of Contine 200

Allopurinol, cimetidine, ciprofloxacin, erythromycin, lithium carbonate, oral contraceptive, propranolol when administered increases serum theophylline level concomitantly and rifampicin decreases serum theophylline level.

 

Contraindications

Theophylline is contraindicated in individuals who have shown hypersensitivity to its components.

 

Side-Effects of Contine 200

The following side effects have been observed:

Gastro-intestinal: Nausea, vomiting, epigastric pain and diarrhoea. Central nervous system: Headache, irritability, restlessness, insomnia, muscles twitching. Cardiovascular: palpitation, tachycardia, hypotension, circulatory failure.

Respiratory: Tachypnoea.

Renal: Potentiation of diuresis.

Others: Alopecia, hyperglycemia, rash etc.

 

Pregnancy

It is not known whether Theophylline can cause fetal harm when administered to pregnant woman. Xanthine should be given to a pregnant woman only if clearly needed.

Precautions

Various interacting medicines and physiologic circumstances that can affect Theophylline clearance must be carefully considered. Before to starting Theophylline therapy, prior to increasing the Theophylline dose, and throughout follow-up, dosage adjustments are required. The dose of Theophylline used for commencement of therapy should be low and gradually raised over time if tolerated.

Storage Conditions

Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.

 

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